Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Jop, Kind"'
Autor:
Kim L. de Luca, Pim M. J. Rullens, Magdalena A. Karpinska, Sandra S. de Vries, Agnieszka Gacek-Matthews, Lőrinc S. Pongor, Gaëlle Legube, Joanna W. Jachowicz, A. Marieke Oudelaar, Jop Kind
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Accurate repair of DNA damage is critical for maintenance of genomic integrity and cellular viability. Because damage occurs non-uniformly across the genome, single-cell resolution is required for proper interrogation, but sensitive detectio
Externí odkaz:
https://doaj.org/article/4a8adea22a094f2e87579c732274e6d0
Accurate repair of DNA damage is critical for maintenance of genomic integrity and cellular survival. Because damage occurs non-uniformly across the genome, single-cell resolution is required for proper interrogation, but sensitive detection has rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9483fb2775a8a37d194688904e5851bf
https://doi.org/10.1101/2023.05.10.540169
https://doi.org/10.1101/2023.05.10.540169
Autor:
Isabel Guerreiro, Franka J. Rang, Yumiko K. Kawamura, Femke C. Groenveld, Ramada E. van Beek, Silke J. A. Lochs, Ellen Boele, Antoine H. M. F. Peters, Jop Kind
The very first days of mammalian embryonic development are accompanied by epigenetic reprogramming and extensive changes in nuclear organization. In particular, genomic regions located at the periphery of the nucleus, termed lamina-associated domains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c52120d36c0e98d625b4889efb1a3ef
https://doi.org/10.1101/2023.02.06.527307
https://doi.org/10.1101/2023.02.06.527307
Autor:
Silke J.A. Lochs, Robin H. van der Weide, Kim L. de Luca, Tessy Korthout, Ramada E. van Beek, Hiroshi Kimura, Jop Kind
Gene expression programs result from the collective activity of many regulatory factors. To obtain insight into the mechanisms that govern gene regulation, it is imperative to study their combined mode of action and interconnectivity. However, it has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48ceea3792b260d90cd336cf2c83a74f
https://doi.org/10.1101/2023.01.18.524584
https://doi.org/10.1101/2023.01.18.524584
Autor:
Erik J. Vrij, Yvonne S. Scholte op Reimer, Laury Roa Fuentes, Isabel Misteli Guerreiro, Viktoria Holzmann, Javier Frias Aldeguer, Giovanni Sestini, Bon-Kyoung Koo, Jop Kind, Clemens A. van Blitterswijk, Nicolas C. Rivron
Publikováno v:
Development (Cambridge), 149(20). Company of Biologists Ltd
Development, 149(20):dev192310. Company of Biologists Ltd
Development
Development, 149(20):dev192310. Company of Biologists Ltd
Development
Embryogenesis is supported by dynamic loops of cellular interactions. Here, we create a partial mouse embryo model to elucidate the principles of epiblast (Epi) and extra-embryonic endoderm co-development (XEn). We trigger naive mouse embryonic stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b9bbcf3f5973f773d129fc7a0148b3
https://pure.knaw.nl/portal/en/publications/68d1c94d-eaa5-4672-8b61-3acbd4bcba2d
https://pure.knaw.nl/portal/en/publications/68d1c94d-eaa5-4672-8b61-3acbd4bcba2d
Autor:
Pim M.J. Rullens, Jop Kind
Publikováno v:
Current Opinion in Cell Biology. 70:51-57
A large proportion of the metazoan genome is spatially segregated at the nuclear periphery through genomic contacts with the nuclear lamina, a thin meshwork of lamin filaments that lines the inner-nuclear membrane. Lamina-associated domains are belie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4456a6987a274bd274e707a83095b827
https://hdl.handle.net/20.500.11755/8dc15879-f111-4b2f-9adf-872bf4dae48b
https://hdl.handle.net/20.500.11755/8dc15879-f111-4b2f-9adf-872bf4dae48b
Publikováno v:
Cells, Vol 8, Iss 3, p 271 (2019)
The nuclear lamina (NL) is a thin meshwork of filaments that lines the inner nuclear membrane, thereby providing a platform for chromatin binding and supporting genome organization. Genomic regions contacting the NL are lamina associated domains (LAD
Externí odkaz:
https://doaj.org/article/4f5df0dcb3874419afedbbd6fcaa4f73
Autor:
Silke J A, Lochs, Jop, Kind
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2532
Spatial genome organization is considered to play an important role in mammalian cells, by guiding gene expression programs and supporting lineage specification. Yet it is still an outstanding question in the field what the direct impact of spatial g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe6946d4880512e201eeaf5b02c663f4
https://pubmed.ncbi.nlm.nih.gov/35867252
https://pubmed.ncbi.nlm.nih.gov/35867252
Autor:
Annalisa Izzo, Kinga Kamieniarz-Gdula, Fidel Ramírez, Nighat Noureen, Jop Kind, Thomas Manke, Bas van Steensel, Robert Schneider
Publikováno v:
Cell Reports, Vol 3, Iss 6, Pp 2142-2154 (2013)
Human cells contain five canonical, replication-dependent somatic histone H1 subtypes (H1.1, H1.2, H1.3, H1.4, and H1.5). Although they are key chromatin components, the genomic distribution of the H1 subtypes is still unknown, and their role in chro
Externí odkaz:
https://doaj.org/article/ae157c8ce19f4046b93876918e4ba3e0
Publikováno v:
Cell Reports. 42:112248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea2bf9986203310a29a2f29845a8014a
https://doi.org/10.1016/j.celrep.2023.112248
https://doi.org/10.1016/j.celrep.2023.112248