Deficiency of aminopeptidase P1 causes behavioral hyperactivity, cognitive deficits, and hippocampal neurodegeneration

Autor: Daesoo Kim, Yi Sul Cho, Yong Chul Bae, Jooyeon Woo, J. Y. Han, Myoung Hwan Kim, Young Soo Bae, Eunjoon Kim, Seok-Kyu Kwon, Sang Ho Yoon

Publikováno v: Genes, Brain and Behavior. 17:126-138

Metabolic diseases affect various organs including the brain. Accumulation or depletion of substrates frequently leads to brain injury and dysfunction. Deficiency of aminopeptidase P1, a cytosolic proline-specific peptidase encoded by the Xpnpep1 gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::28bfa774165cb1a6150593d127b8ef67
https://doi.org/10.1111/gbb.12419

4.1 A 640×480 dynamic vision sensor with a 9µm pixel and 300Meps address-event representation

Autor: Kyoobin Lee, Jooyeon Woo, Chang-Woo Shin, Bongki Son, Junseok Kim, Lee Hyunku, Jung Hee-Jae, Keunju Park, Park Jin-Man, Yohan Roh, Yibing Wang, Yunjae Suh, Sungho Kim, Hyunsurk Ryu, Ilia Ovsiannikov

Publikováno v: ISSCC

We report a VGA dynamic vision sensor (DVS) with a 9µm pixel, developed through a digital as well as an analog implementation. DVS systems in the literature try to increase spatial resolution up to QVGA [1–2] and data rates up to 50 million events

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f3f0b76e16be1773678d65b6dd268b7d
https://doi.org/10.1109/isscc.2017.7870263

The adhesion protein IgSF9b is coupled to neuroligin 2 via S-SCAM to promote inhibitory synapse development

Autor: Seungwon Choi, Ann Marie Craig, Jin Young Bae, Joo Hyun Park, Hyun Kim, Jaewon Ko, Yong Chul Bae, Yeunkum Lee, Jooyeon Woo, Dongmin Lee, Hideto Takahashi, Dilja D. Krueger, Seok-Kyu Kwon, Jungyong Nam, Sunghoe Chang, Eunjoon Kim, Myoung Hwan Kim

Publikováno v: The Journal of Cell Biology

IgSF9b forms a novel subsynaptic domain for adhesion that links to the gephyrin- and GABAA receptor–containing domain to promote inhibitory synaptic development.
Synaptic adhesion molecules regulate diverse aspects of synapse formation and mai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e6738d3e27b375f44789dc119d0052
https://doi.org/10.1083/jcb.201209132

SALM5 trans-synaptically interacts with LAR-RPTPs in a splicing-dependent manner to regulate synapse development

Autor: Sang Min Jeon, Seok-Kyu Kwon, Yan Li, Eunjoon Kim, Ho Min Kim, Doyoun Kim, Jooyeon Woo, Seonggyu Lee, Won Mah, Kwangwook Cho, Ji Won Um, Yoo Sung Song, Jungyong Nam, Daniel J. Whitcomb, Jaewon Ko, Yeonsoo Choi

Publikováno v: Choi, Y, Nam, J, Whitcomb, D, Sung Song, Y, Kim, D, Jeon, S, Um, J W, Lee, S-G, Woo, J, Kwon, S-K, Li, Y, Ma, W, Kim, H M, Ko, J, Cho, K & Kim, E 2016, ' SALM5 trans-synaptically interacts with LAR-RPTPs in a splicing-dependent manner to regulate synapse development ', Scientific Reports, vol. 6, 26676 . https://doi.org/10.1038/srep26676
Scientific Reports

Synaptogenic adhesion molecules play critical roles in synapse formation. SALM5/Lrfn5, a SALM/Lrfn family adhesion molecule implicated in autism spectrum disorders (ASDs) and schizophrenia, induces presynaptic differentiation in contacting axons, but

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4520851732172318096454f91dd7bb65
https://doi.org/10.1038/srep26676

Trans-synaptic adhesion between NGL-3 and LAR regulates the formation of excitatory synapses

Autor: Anthone W. Dunah, Seho Kim, Seungwon Choi, Jae-Ran Lee, Seok-Kyu Kwon, Morgan Sheng, Jooyeon Woo, Eunjoon Kim

Publikováno v: Nature Neuroscience. 12:428-437

Synaptic adhesion molecules regulate multiple steps of synapse formation and maturation. The great diversity of neuronal synapses predicts the presence of a large number of adhesion molecules that control synapse formation through trans-synaptic and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a621bb5013acbbfb892a8dd7471b27e
https://doi.org/10.1038/nn.2279