Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jooyeon Sohn"'
Publikováno v:
Immunity & Ageing, Vol 19, Iss 1, Pp 1-5 (2022)
Abstract Immunosenescence is an age-dependent decline in immune functions and hallmark of aging in diverse species, ranging from invertebrates to mammals. However, identifying the factors responsible for immunosenescence is challenging because of the
Externí odkaz:
https://doaj.org/article/a0313fcc56134f6294a568562fe3a704
Autor:
Minjeong Kang, Raisa Kharbash, Ja Min Byun, Jaemin Jeon, Ahsan Ausaf Ali, Doyeong Ku, Jimin Yoon, Yongsuk Ku, Jooyeon Sohn, Seung-Jae V. Lee, Dong-Yeop Shin, Youngil Koh, Sung-Soo Yoon, Junshik Hong, Yoosik Kim
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 370-383 (2022)
Hypomethylating agents (HMAs), such as azacitidine and decitabine, induce cancer cell death by demethylating DNAs to promote the expression of tumor-suppressor genes. HMAs also reactivate the transcription of endogenous double-stranded RNAs (dsRNAs)
Externí odkaz:
https://doaj.org/article/7b76f007b84a4874afda364767dcb0ed
Publikováno v:
Molecules and Cells
Aging is associated with functional and structural declines in organisms over time. Organisms as diverse as the nematode Caenorhabditis elegans and mammals share signaling pathways that regulate aging and lifespan. In this review, we discuss recent c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48960748cc18bc5cf0822d611ae3935
https://doi.org/10.14348/molcells.2021.0080
https://doi.org/10.14348/molcells.2021.0080
Publikováno v:
Autophagy
The Golgi apparatus regulates the process of modification and subcellular localization of macromolecules, including proteins and lipids. Aberrant protein sorting caused by defects in the Golgi leads to various diseases in mammals. However, the role o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17786417e245f6726dbbffad71935709
https://doi.org/10.1080/15548627.2022.2039523
https://doi.org/10.1080/15548627.2022.2039523
Autor:
Dongyeop Lee, Hyun-Jun Nam, Chanhee Kang, Jooyeon Sohn, Malene Hansen, Linnea M Adams, Yujin Lee, Eun Ji Kim, Seung-Yeol Park, Murat Artan, Dae-Eun Jeong, Dong Jin Moon, Wooseon Hwang, Seung-Jae Lee, Joo-Yeon Yoo, Mihwa Seo, Jeonghun Yeom, Yoonji Jung, Ozlem Altintas, Youngjae Ryu, Sang Ki Park, Cheolju Lee, Keunhee Seo, Sanguk Kim, Chang Man Ha, Seong Kyu Han, Nari Kim, Ara B. Hwang, Sungeun Ju
Publikováno v:
Science Advances
Description
MON-2, which mediates Golgi-endosome trafficking, mediates mitochondrial inhibition–induced longevity by enhancing autophagy.
The Golgi apparatus plays a central role in trafficking cargoes such as proteins and lipids. Defects
MON-2, which mediates Golgi-endosome trafficking, mediates mitochondrial inhibition–induced longevity by enhancing autophagy.
The Golgi apparatus plays a central role in trafficking cargoes such as proteins and lipids. Defects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27f1fa669943e92aaf3320c27f96c02d
https://doi.org/10.1126/sciadv.abj8156
https://doi.org/10.1126/sciadv.abj8156