Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Joost eVerhaagen"'
Autor:
Stefan A. Hoyng, Fred eDe Winter, Martijn R. Tannemaat, Bas eBlits, Martijn J.A. Malessy, Joost eVerhaagen
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 8 (2015)
Clinical phase I/II studies have demonstrated the safety of gene therapy for a variety of central nervous system disorders, including Canavan’s, Parkinson’s and Alzheimer’s disease, retinal diseases and pain. The majority of gene therapy studie
Externí odkaz:
https://doaj.org/article/2edef3eace044fbd9d25f8087fcf9fb3
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 8 (2014)
Traumatic injury of the central nervous system (CNS) has severe impact on the patients’ quality of life and initiates many molecular and cellular changes at the site of insult. Traumatic CNS injury results in direct damage of the axons of CNS neuro
Externí odkaz:
https://doaj.org/article/a2c6fd9431524d178abb380ce6efacf5
Publikováno v:
Frontiers in Neuroscience, Vol 8 (2014)
Amyotrophic Lateral Sclerosis (ALS) is being redefined as a distal axonopathy, in that many molecular changes influencing motor neuron degeneration occur at the neuromuscular junction (NMJ) at very early stages of the disease prior to symptom onset.
Externí odkaz:
https://doaj.org/article/d71a9a5e717c47d7a2b996707794cdf9
Autor:
Ronald E. Van Kesteren, Matthew R.J. Mason, Harold D. MacGillavry, August B Smit, Joost eVerhaagen
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 4 (2011)
The regenerative capacity of injured neurons in the central nervous system is limited due to the absence of a robust neuron-intrinsic injury-induced gene response that supports axon regeneration. In peripheral neurons axotomy induces a large cohort o
Externí odkaz:
https://doaj.org/article/bf58ecb65e2946eaa34235c7e79574a6