Zobrazeno 1 - 10
of 340
pro vyhledávání: '"Joost Wiersinga"'
Autor:
Milan L Ridderikhof, Prabath W B Nanayakkara, Robert de Jonge, Joost Wiersinga, Michiel Schinkel, Kaoutar Azijli, Anneroos W Boerman, Anuschka Y van der Zaag, Birgit Lissenberg-Witte, Sheena C Bhagirath, Ketan Paranjape, Mei Lie, Rogier Schade
Publikováno v:
BMJ Open, Vol 14, Iss 5 (2024)
Introduction The liberal use of blood cultures in emergency departments (EDs) leads to low yields and high numbers of false-positive results. False-positive, contaminated cultures are associated with prolonged hospital stays, increased antibiotic usa
Externí odkaz:
https://doaj.org/article/dddf62afa4cc44ca8c6d32c1d215cdcb
Autor:
Michiel Schinkel, Frank C. Bennis, Anneroos W. Boerman, W. Joost Wiersinga, Prabath W. B. Nanayakkara
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-4 (2023)
Abstract This study is a simple illustration of the benefit of averaging over cohorts, rather than developing a prediction model from a single cohort. We show that models trained on data from multiple cohorts can perform significantly better in new s
Externí odkaz:
https://doaj.org/article/5f4ee011d1f343b2acce605bd3f0ef00
Autor:
Tom D. Y. Reijnders, Alex R. Schuurman, Jan Verhoeff, Marlous van den Braber, Renée A. Douma, Daniël R. Faber, Alberta G. A. Paul, W. Joost Wiersinga, Anno Saris, Juan J. Garcia Vallejo, Tom van der Poll
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundCommunity-acquired pneumonia (CAP) represents a major health burden worldwide. Dysregulation of the immune response plays an important role in adverse outcomes in patients with CAP.MethodsWe analyzed peripheral blood mononuclear cells by 36
Externí odkaz:
https://doaj.org/article/1c395277784f45d4a2292698566e39b7
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-8 (2023)
Abstract Sepsis involves the dynamic interplay between a pathogen, the host response, the failure of organ systems, medical interventions and a myriad of other factors. This together results in a complex, dynamic and dysregulated state that has remai
Externí odkaz:
https://doaj.org/article/65d359aab5d54c32a857bffb22079ad1
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-7 (2023)
Abstract This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2023. Other selected articles can be found online at https://www.biomedcentral.com/collections/annualupdate2023 . Further information
Externí odkaz:
https://doaj.org/article/a21acff965344208b7b24cda3228ee7b
Autor:
Jelmer Savelkoel, Rita O. Oladele, Chiedozie K. Ojide, Rebecca F. Peters, Daan W. Notermans, Justina O. Makinwa, Maaike C. de Vries, Marion A.E. Sunter, Sébastien Matamoros, Nasiru Abdullahi, Uche S. Unigwe, Alani S. Akanmu, W. Joost Wiersinga, Emma Birnie
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 5, Pp 1073-1075 (2023)
Melioidosis, caused by the soil-dwelling bacterium Burkholderia pseudomallei, is predicted to be endemic in Nigeria but is only occasionally reported. This report documents the systematic identification of the presence of B. pseudomallei and B. thail
Externí odkaz:
https://doaj.org/article/03516753033d43eba839d596bab8d47d
Autor:
Elske Sieswerda, Hannelore I. Bax, Jacobien J. Hoogerwerf, Mark G. J. de Boer, Marja Boermeester, Marc J. M. Bonten, Douwe Dekker, Roy Gerth van Wijk, Nicole P. Juffermans, Marnix Kuindersma, Paul D. van der Linden, Damian C. Melles, Peter Pickkers, Jeroen A. Schouten, Jasper R. Rebel, Arthur R. H. van Zanten, Jan M. Prins, W. Joost Wiersinga
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-16 (2022)
Abstract Background The Dutch Working Party on Antibiotic Policy (SWAB) in collaboration with relevant professional societies, has updated their evidence-based guidelines on empiric antibacterial therapy of sepsis in adults. Methods Our multidiscipli
Externí odkaz:
https://doaj.org/article/428bc82ef7f045c2b74f25abb5e6bb8a
Autor:
Alex R. Schuurman, Joe M. Butler, Erik H.A. Michels, Natasja A. Otto, Xanthe Brands, Bastiaan W. Haak, Fabrice Uhel, Augustijn M. Klarenbeek, Daniël R. Faber, Bauke V. Schomakers, Michel van Weeghel, Alex F. de Vos, Brendon P. Scicluna, Riekelt H. Houtkooper, W. Joost Wiersinga, Tom van der Poll
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107181- (2023)
Summary: Neutrophils are potent immune cells with key antimicrobial functions. Previous in vitro work has shown that neutrophil effector functions are mainly fueled by intracellular glycolysis. Little is known about the state of neutrophils still in
Externí odkaz:
https://doaj.org/article/4e949718e4164c9fb99adf50b5dffd0d
Autor:
Anna G. Kaal, Linde op de Hoek, Davinia T. Hochheimer, Corline Brouwers, W. Joost Wiersinga, Dominic Snijders, Katrijn L. Rensing, Christel E. van Dijk, Ewout W. Steyerberg, Cees van Nieuwkoop
Publikováno v:
ERJ Open Research, Vol 9, Iss 3 (2023)
Background The Pneumonia Severity Index (PSI) and the CURB-65 score assess disease severity in patients with community-acquired pneumonia (CAP). We compared the clinical performance of both prognostic scores according to clinical outcomes and admissi
Externí odkaz:
https://doaj.org/article/3729246df2864600ab5124f8f100b23f
Autor:
Justin de Brabander, Erik H. A. Michels, Christine C. A. van Linge, Osoul Chouchane, Renée A. Douma, Tom D. Y. Reijnders, Alex R. Schuurman, Tjitske S. R. van Engelen, Amsterdam UMC COVID-19 biobank study group, W. Joost Wiersinga, Tom van der Poll
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-7 (2022)
Abstract Dexamethasone improves clinical outcomes in COVID-19 patients requiring supplementary oxygen. We investigated possible mechanisms of action by comparing sixteen plasma host response biomarkers in general ward patients before and after implem
Externí odkaz:
https://doaj.org/article/154585d74b9c4aa5b3cd44c9f52dad8a