Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Joost W. Gouw"'
Autor:
Rosana B. R. Ferreira, Yanet Valdez, Brian K. Coombes, Subash Sad, Joost W. Gouw, Eric M. Brown, Yuling Li, Guntram A. Grassl, L. Caetano M. Antunes, Navkiran Gill, Mimi Truong, Roland Scholz, Lisa A. Reynolds, Laskshmi Krishnan, Ahmed A. Zafer, Neta Sal-Man, Michael J. Lowden, Sigrid D. Auweter, Leonard J. Foster, B. Brett Finlay
Publikováno v:
mBio, Vol 6, Iss 5 (2015)
ABSTRACT Nontyphoidal Salmonella enterica (NTS) infections are a major burden to global public health, as they lead to diseases ranging from gastroenteritis to systemic infections and there is currently no vaccine available. Here, we describe a highl
Externí odkaz:
https://doaj.org/article/ac70c9215c0d45ce813794f8a4a04cbb
Autor:
Nat F. Brown, Lindsay D. Rogers, Kristy L. Sanderson, Joost W. Gouw, Elizabeth L. Hartland, Leonard J. Foster
Publikováno v:
mBio, Vol 5, Iss 5 (2014)
ABSTRACT The transcription factors HilA and SsrB activate expression of two type III secretion systems (T3SSs) and cognate effectors that reprogram host cell functions to benefit infecting Salmonella in the host. These transcription factors, the secr
Externí odkaz:
https://doaj.org/article/2ef5f326759b4c7d88ad8ac6ea509158
Autor:
Aude Tartiere, Harm Wopereis, Julie Piquenot, Jan Knol, Daniel Chelsky, Sebastian Tims, Joost W. Gouw, Laetitia Cortes
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences 20 (2019) 6
Volume 20
Issue 6
International Journal of Molecular Sciences, Vol 20, Iss 6, p 1430 (2019)
International Journal of Molecular Sciences, 20(6)
International Journal of Molecular Sciences 20 (2019) 6
Volume 20
Issue 6
International Journal of Molecular Sciences, Vol 20, Iss 6, p 1430 (2019)
International Journal of Molecular Sciences, 20(6)
A metaproteomic analysis was conducted on the fecal microbiome of eight infants to characterize global protein and pathway expression. Although mass spectrometry-based proteomics is now a routine tool, analysis of the microbiome presents specific tec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8859b9efec10d8e04d6f478d321ce68e
https://pubmed.ncbi.nlm.nih.gov/30901843
https://pubmed.ncbi.nlm.nih.gov/30901843
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1828(1):23-34
Connexins require an integrated network for protein synthesis, assembly, gating, internalization, degradation and feedback control that are necessary to regulate the biosynthesis, and turnover of gap junction channels. At the most fundamental level,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d536d23e5a720d1180157ea369cf4457
Autor:
Albert J. R. Heck, A. F. Maarten Altelaar, Paul J. Boersema, Joost W. Gouw, Darryl J. Pappin, Philip L. Ross, Nadia Taouatas, Shabaz Mohammed
In this work, we explore the potential of the metalloendopeptidase Lys-N for MALDI-MS/MS proteomics applications. Initially we digested a HEK293 cellular lysate with Lys-N and, for comparison, in parallel with the protease Lys-C. The resulting peptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8726be8a5ff838821d71ac747a1c47ed
https://doi.org/10.1074/mcp.m800249-mcp200
https://doi.org/10.1074/mcp.m800249-mcp200
Autor:
Poupak Dadvar, Reinout Raijmakers, Albert J. R. Heck, Sarah Pelletier, Klaus Rumpel, Joost W. Gouw
Publikováno v:
ChemMedChem. 5:1927-1936
Inhibitors of phosphodiesterase 5 (PDE5) are widely used for the treatment of erectile dysfunction and pulmonary hypertension. The commercially available inhibitors are effective, well-tolerated drugs, but differ in their phosphodiesterase specificit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b283b396619693637fefa9bb2df55d9f
https://doi.org/10.1002/cmdc.201000303
https://doi.org/10.1002/cmdc.201000303
Autor:
Jesper V. Olsen, Shao En Ong, Jürgen Cox, Kristoffer T.G. Rigbolt, Peter Mortensen, Jakob Bunkenborg, Jens S. Andersen, Albert J. R. Heck, Matthias Mann, Blagoy Blagoev, Leonard J. Foster, Joost W. Gouw
Publikováno v:
Journal of Proteome Research
Journal of Proteome Research; Vol 9
Mortensen, P, Gouw, J W, Olsen, J V, Ong, S-E, Rigbolt, K T G, Bunkenborg, J, Cox, J, Foster, L J, Heck, A J R, Blagoev, B, Andersen, J S & Mann, M 2010, ' MSQuant, an Open Source Platform for Mass Spectrometry-Based Quantitative Proteomics ', Journal of Proteome Research, vol. 9, no. 1, pp. 393-403 . https://doi.org/10.1021/pr900721e
Journal of Proteome Research; Vol 9
Mortensen, P, Gouw, J W, Olsen, J V, Ong, S-E, Rigbolt, K T G, Bunkenborg, J, Cox, J, Foster, L J, Heck, A J R, Blagoev, B, Andersen, J S & Mann, M 2010, ' MSQuant, an Open Source Platform for Mass Spectrometry-Based Quantitative Proteomics ', Journal of Proteome Research, vol. 9, no. 1, pp. 393-403 . https://doi.org/10.1021/pr900721e
Mass spectrometry-based proteomics critically depends on algorithms for data interpretation. A current bottleneck in the rapid advance of proteomics technology is the closed nature and slow development cycle of vendor-supplied software solutions. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bae1752ad64a0b54a0aed0fefc8451d
Autor:
Albert J. R. Heck, Joost W. Gouw, Martijn W. H. Pinkse, Jeroen Krijgsveld, C. Peter Verrijzer, Harmjan R. Vos, Yuri M. Moshkin
Publikováno v:
Molecular & Cellular Proteomics, 8(7), 1566-1578. American Society for Biochemistry and Molecular Biology Inc.
An important hallmark in embryonic development is characterized by the maternal-to-zygotic transition (MZT) where zygotic transcription is activated by a maternally controlled environment. Post-transcriptional and translational regulation is critical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9907d66ea865acefbc644c586769f2f3
https://hdl.handle.net/1765/25193
https://hdl.handle.net/1765/25193
Autor:
Shabaz Mohammed, Joost W. Gouw, Albert J. R. Heck, Henk W. P. van den Toorn, Bas van Breukelen
Publikováno v:
Journal of Proteomics & Bioinformatics. :379-388
Electron transfer dissociation (ETD) of peptide ions has been introduced as a tool for mass spectrometry based peptide sequencing, complementary to the commonly used collision induced dissociation (CID). It has been proposed that ETD may have better
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10c39c6308bd2d923416a8baf3dad3e5
https://doi.org/10.4172/jpb.1000047
https://doi.org/10.4172/jpb.1000047
Autor:
Andreas Otto, Uwe Völker, Joost W. Gouw, Michael Hecker, Annette Dreisbach, Dörte Becher, Elke Hammer, Alexander Teumer
Publikováno v:
PROTEOMICS. 8:2062-2076
Bacillus subtilis has been developed as a model system for physiological proteomics. However, thus far these studies have mainly been limited to cytoplasmic, extracellular, and cell-wall attached proteins. Although being certainly important for cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47965b528e748940b21974b2984e27c4
https://doi.org/10.1002/pmic.200701081
https://doi.org/10.1002/pmic.200701081