Výsledky vyhledávání - "Joost Vaneman"

Akademický článek

Design and Preclinical Evaluation of a Nanoparticle Vaccine against Respiratory Syncytial Virus Based on the Attachment Protein G

Autor: Richard Voorzaat, Freek Cox, Daan van Overveld, Lam Le, Lisanne Tettero, Joost Vaneman, Mark J. G. Bakkers, Johannes P. M. Langedijk

Publikováno v: Vaccines, Vol 12, Iss 3, p 294 (2024)

Human respiratory syncytial virus (RSV) poses a significant human health threat, particularly to infants and the elderly. While efficacious vaccines based on the F protein have recently received market authorization, uncertainties remain regarding th

Externí odkaz: https://doaj.org/article/7b3cd1758c084380a03c5b0855313ad3

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Akademický článek

Maternal antibodies protect offspring from severe influenza infection and do not lead to detectable interference with subsequent offspring immunization

Autor: Joan E. M. van der Lubbe, Jessica Vreugdenhil, Sarra Damman, Joost Vaneman, Jaco Klap, Jaap Goudsmit, Katarina Radošević, Ramon Roozendaal

Publikováno v: Virology Journal, Vol 14, Iss 1, Pp 1-12 (2017)

Abstract Background Various studies have shown that infants under the age of 6 months are especially vulnerable for complications due to influenza. Currently there are no vaccines licensed for use in this age group. Vaccination of pregnant women duri

Externí odkaz: https://doaj.org/article/eca3622f79424008814481b2c9992526

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Akademický článek

Restrained expansion of the recall germinal center response as biomarker of protection for influenza vaccination in mice.

Autor: Laurens P Kil, Joost Vaneman, Joan E M van der Lubbe, Dominika Czapska-Casey, Jeroen T B M Tolboom, Ramon Roozendaal, Roland C Zahn, Harmjan Kuipers, Laura Solforosi

Publikováno v: PLoS ONE, Vol 14, Iss 11, p e0225063 (2019)

Correlates of protection (CoP) are invaluable for iterative vaccine design studies, especially in pursuit of complex vaccines such as a universal influenza vaccine (UFV) where a single antigen is optimized to elicit broad protection against many vira

Externí odkaz: https://doaj.org/article/2c43560738414ddbbd753da589cbbf12

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Immunogenicity and efficacy of one and two doses of Ad26.COV2.S COVID vaccine in adult and aged NHP

Publikováno v: Journal of Experimental Medicine
The Journal of Experimental Medicine
Journal of Experimental Medicine, 218(7). ROCKEFELLER UNIV PRESS

While single-dose COVID-19 vaccines are preferred, two-dose regimens may improve efficacy. Immunogenicity of Ad26.COV2.S is improved in NHPs after a second dose, whereas both regimens protect animals against SARS-CoV-2 disease and elicit neutralizing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a2265afab602b4bdbf9da777bf8c387
https://doi.org/10.1084/jem.20202756

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Maternal antibodies protect offspring from severe influenza infection and do not lead to detectable interference with subsequent offspring immunization

Autor: Ramon Roozendaal, Joan E. M. van der Lubbe, Joost Vaneman, Katarina Radosevic, Jaap Goudsmit, Jessica Vreugdenhil, Sarra Damman, J.M. Klap

Publikováno v: Virology Journal, Vol 14, Iss 1, Pp 1-12 (2017)
Virology Journal

Background Various studies have shown that infants under the age of 6 months are especially vulnerable for complications due to influenza. Currently there are no vaccines licensed for use in this age group. Vaccination of pregnant women during the la

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a656b2e91df2503177a84ebd8ce44c
http://link.springer.com/article/10.1186/s12985-017-0787-4

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Flowcytometry staining protocol for the identification of B- or T-cell subsets in mice. v1

Autor: Joost Vaneman

This staining procedure was established to assess the frequencies of various B- or T- cell subsets in single cell suspensions prepared from murine spleen or lymph nodes. The protocol included describes the required steps to successfully stain samples

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c87d40ecdcafe263241f695237386b73
https://doi.org/10.17504/protocols.io.7szhnf6

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Haemagglutinin ELISA v1

Autor: Joost Vaneman

This ELISA was established to measure antibody titers against the haemagglutinin (HA) protein of influenza viruses in murine serum. This protocol describes the steps required to successfully perform the assay.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14d949bec54b6b6110ac2117fa1e3f8c
https://doi.org/10.17504/protocols.io.7g5hjy6

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Haemagglutinin Competition ELISA v1

Autor: Joost Vaneman

This Competition ELISA was established to measure CR9114-like antibodies in murine serum. CR9114 is a monoclonal antibody which binds to a conserved stem region of the hemagglutinin (HA) protein of influenza viruses. As the binding site of CR9114 is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::069852760033da7969b5c23d5e0144b2
https://doi.org/10.17504/protocols.io.7hihj4e

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