Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Joost M. Riphagen"'
Autor:
Nina Engels-Domínguez, Elouise A. Koops, Stephanie Hsieh, Emma E. Wiklund, Aaron P. Schultz, Joost M. Riphagen, Prokopis C. Prokopiou, Bernard J. Hanseeuw, Dorene M. Rentz, Reisa A. Sperling, Keith A. Johnson, Heidi I. L. Jacobs
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-14 (2024)
Abstract Background Autopsy work indicates that the widely-projecting noradrenergic pontine locus coeruleus (LC) is among the earliest regions to accumulate hyperphosphorylated tau, a neuropathological Alzheimer’s disease (AD) hallmark. This early
Externí odkaz:
https://doaj.org/article/1a2a23bb5bfe4f028d41e04abb34676d
Publikováno v:
NeuroImage: Clinical, Vol 33, Iss , Pp 102948- (2022)
The recently described biological framework of Alzheimer’s disease (AD) emphasizes three types of pathology to characterize this disorder, referred to as the ‘amyloid/tau/neurodegeneration’ (A-T-N) status. The ‘neurodegenerative’ component
Externí odkaz:
https://doaj.org/article/fc95c1eaed6b4214a3626dcf9f439216
Autor:
Roy W. E. Van Hooren, Joost M. Riphagen, Heidi I. L. Jacobs, For the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-12 (2018)
Abstract Background Amyloid-beta (Aβ) has a dose-response relationship with cognition in healthy adults. Additionally, the levels of functional connectivity within and between brain networks have been associated with cognitive performance in healthy
Externí odkaz:
https://doaj.org/article/33b29b4e01284982876272c738e6276e
Publikováno v:
Neurobiology of Aging, 114, 105-112. Elsevier Science
Neurobiol Aging
Neurobiol Aging
White matter signal abnormalities (WMSA), either hypo- or hyperintensities in MRI imaging, are considered a proxy of cerebrovascular pathology and contribute to, and modulate, the clinical presentation of Alzheimer's disease (AD), with cognitive dysf
Autor:
Maxime Van Egroo, Joost M. Riphagen, Nicholas J. Ashton, Shorena Janelidze, Reisa A. Sperling, Keith A. Johnson, Hyun-Sik Yang, David A. Bennett, Kaj Blennow, Oskar Hansson, Henrik Zetterberg, Heidi I. L. Jacobs
Publikováno v:
Molecular Psychiatry. Nature Publishing Group
Autopsy data indicate that the locus coeruleus (LC) is one of the first sites in the brain to accumulate hyperphosphorylated tau pathology, with the rostral part possibly being more vulnerable in the earlier stages of the disease. Taking advantage of
Autor:
Nina, Engels-Domínguez, Elouise A, Koops, Prokopis C, Prokopiou, Maxime, Van Egroo, Christoph, Schneider, Joost M, Riphagen, Tarun, Singhal, Heidi I L, Jacobs
Publikováno v:
Neuroscience and Biobehavioral Reviews, 144:104998. Elsevier Science
Primary prevention trials have shifted their focus to the earliest stages of Alzheimer's disease (AD). Autopsy data indicates that the neuromodulatory subcortical systems' (NSS) nuclei are specifically vulnerable to initial tau pathology, indicating
Autor:
Prokopis C. Prokopiou, Nina Engels, Christoph Schneider, Aaron P. Schultz, Jorge Sepulcre, Joost M. Riphagen, Elouise A. Koops, Kathryn V. Papp, Georges El Fakhri, Dorene M. Rentz, Reisa A. Sperling, Keith A. Johnson, Heidi I.L. Jacobs
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Joost M. Riphagen, Jasmeer P. Chhatwal, Alex Becker, Kenneth Kwong, Nina Engels, Wai‐Ying Wendy Yau, Prokopis C. Prokopiou, Christoph Schneider, Elouise A. Koops, Dorene M. Rentz, Reisa A. Sperling, Keith A. Johnson, Heidi I.L. Jacobs
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Nina Engels, Stephanie Hsieh, Christoph Schneider, Prokopis C. Prokopiou, Aaron P. Schultz, Joost M. Riphagen, Elouise A. Koops, Bernard Hanseeuw, Dorene M. Rentz, Reisa A. Sperling, Keith A. Johnson, Heidi I.L. Jacobs
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Heidi I.L. Jacobs, Joost M. Riphagen, Nicholas J. Ashton, Shorena Janelidze, Reisa A. Sperling, Keith A. Johnson, Hyun‐Sik Yang, Kaj Blennow, Oskar Hansson, Henrik Zetterberg, Maxime Van Egroo
Publikováno v:
Alzheimer's & Dementia. 18