The biodistribution of polystyrene nanoparticles administered intravenously in the chicken embryo

Autor: Meiru Wang, Shuhao Chen, Shixiong Cheng, Tom A.P. Nederstigt, Robert E. Poelmann, Marco C. DeRuiter, Gerda E.M. Lamers, Joost J. Willemse, Chiara Mascitelli, Martina G. Vijver, Michael K. Richardson

Publikováno v: Environment International, Vol 188, Iss , Pp 108723- (2024)

Nanoplastics can cause severe malformations in chicken embryos. To improve our understanding of the toxicity of nanoplastics to embryos, we have studied their biodistribution in living chicken embryos. We injected the embryos in the vitelline vein at

Externí odkaz: https://doaj.org/article/f39ba361ead14df896bcc88cf5f2972b

Semisynthetic guanidino lipoglycopeptides with potent in vitro and in vivo antibacterial activity.

Autor: van Groesen E; Biological Chemistry Group, Institute of Biology Leiden, Leiden University, 2300 RA Leiden, Netherlands., Mons E; Biological Chemistry Group, Institute of Biology Leiden, Leiden University, 2300 RA Leiden, Netherlands., Kotsogianni I; Biological Chemistry Group, Institute of Biology Leiden, Leiden University, 2300 RA Leiden, Netherlands., Arts M; Institute for Pharmaceutical Microbiology, University Hospital Bonn, University of Bonn, 53113 Bonn, Germany., Tehrani KHME; Biological Chemistry Group, Institute of Biology Leiden, Leiden University, 2300 RA Leiden, Netherlands., Wade N; Biological Chemistry Group, Institute of Biology Leiden, Leiden University, 2300 RA Leiden, Netherlands., Lysenko V; Biological Chemistry Group, Institute of Biology Leiden, Leiden University, 2300 RA Leiden, Netherlands., Stel FM; Biological Chemistry Group, Institute of Biology Leiden, Leiden University, 2300 RA Leiden, Netherlands., Zwerus JT; Biological Chemistry Group, Institute of Biology Leiden, Leiden University, 2300 RA Leiden, Netherlands., De Benedetti S; Institute for Pharmaceutical Microbiology, University Hospital Bonn, University of Bonn, 53113 Bonn, Germany., Bakker A; Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University, 2300 RA Leiden, Netherlands., Chakraborty P; Department of Molecular Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, 9700 AB Groningen, Netherlands., van der Stelt M; Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University, 2300 RA Leiden, Netherlands., Scheffers DJ; Department of Molecular Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, 9700 AB Groningen, Netherlands., Gooskens J; Department of Medical Microbiology, Leiden University Center for Infectious Diseases (LUCID), Leiden University Medical Center, 2333 ZA Leiden, Netherlands., Smits WK; Experimental Bacteriology, Leiden University Center for Infectious Diseases (LUCID), Leiden University Medical Center, 2333 ZA Leiden, Netherlands., Holden K; Evotec (U.K.) Ltd., Alderley Park, Macclesfield, Cheshire, SK10 4TG UK., Gilmour PS; The Drug Development Team, 2321 DK Leiden, Netherlands., Willemse J; Institute of Biology Leiden, Leiden University, 2300 RA Leiden, Netherlands., Hitchcock CA; 6 Carnoustie Close, Molehill Road, Chestfield, Whitstable, Kent CT5 3PW, UK., van Hasselt JGC; Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, 2300 RA Leiden, Netherlands., Schneider T; Institute for Pharmaceutical Microbiology, University Hospital Bonn, University of Bonn, 53113 Bonn, Germany., Martin NI; Biological Chemistry Group, Institute of Biology Leiden, Leiden University, 2300 RA Leiden, Netherlands.

Publikováno v: Science translational medicine [Sci Transl Med] 2024 Aug 07; Vol. 16 (759), pp. eabo4736. Date of Electronic Publication: 2024 Aug 07.

Polyester degradation by soil bacteria: identification of conserved BHETase enzymes in Streptomyces.

Autor: Verschoor JA; Molecular Biotechnology, Institute of Biology, Leiden University, Sylviusweg 72, 2333BE, Leiden, The Netherlands., Croese MRJ; Molecular Biotechnology, Institute of Biology, Leiden University, Sylviusweg 72, 2333BE, Leiden, The Netherlands., Lakemeier SE; Molecular Biotechnology, Institute of Biology, Leiden University, Sylviusweg 72, 2333BE, Leiden, The Netherlands., Mugge A; Molecular Biotechnology, Institute of Biology, Leiden University, Sylviusweg 72, 2333BE, Leiden, The Netherlands., Burgers CMC; Molecular Biotechnology, Institute of Biology, Leiden University, Sylviusweg 72, 2333BE, Leiden, The Netherlands., Innocenti P; Molecular Biotechnology, Institute of Biology, Leiden University, Sylviusweg 72, 2333BE, Leiden, The Netherlands., Willemse J; Molecular Biotechnology, Institute of Biology, Leiden University, Sylviusweg 72, 2333BE, Leiden, The Netherlands., Crooijmans ME; Molecular Biotechnology, Institute of Biology, Leiden University, Sylviusweg 72, 2333BE, Leiden, The Netherlands., van Wezel GP; Molecular Biotechnology, Institute of Biology, Leiden University, Sylviusweg 72, 2333BE, Leiden, The Netherlands., Ram AFJ; Molecular Biotechnology, Institute of Biology, Leiden University, Sylviusweg 72, 2333BE, Leiden, The Netherlands., de Winde JH; Molecular Biotechnology, Institute of Biology, Leiden University, Sylviusweg 72, 2333BE, Leiden, The Netherlands. j.h.de.winde@biology.leidenuniv.nl.

Publikováno v: Communications biology [Commun Biol] 2024 Jun 12; Vol. 7 (1), pp. 725. Date of Electronic Publication: 2024 Jun 12.

Taxonomic and metabolic diversity of Actinomycetota isolated from faeces of a 28,000-year-old mammoth.

Autor: van Bergeijk DA; Department of Microbiology, Immunology and Transplantation (Laboratory of Molecular Bacteriology), KU Leuven, Leuven, Belgium.; Center for Microbiology, VIB, Leuven, Belgium., Augustijn HE; Institute of Biology, Leiden University, Leiden, The Netherlands.; Bioinformatics Group, Wageningen University, Wageningen, The Netherlands., Elsayed SS; Institute of Biology, Leiden University, Leiden, The Netherlands., Willemse J; Institute of Biology, Leiden University, Leiden, The Netherlands., Carrión VJ; Institute of Biology, Leiden University, Leiden, The Netherlands.; Department of Microbiology, University of Málaga, Málaga, Spain.; Department of Microbial Ecology, Netherlands Institute of Ecology, Wageningen, The Netherlands., Du C; Institute of Biology, Leiden University, Leiden, The Netherlands., Urem M; Institute of Biology, Leiden University, Leiden, The Netherlands., Grigoreva LV; North-Eastern Federal University, Yakutsk, Russia., Cheprasov MY; North-Eastern Federal University, Yakutsk, Russia., Grigoriev S; North-Eastern Federal University, Yakutsk, Russia., Jansen H; Future Genomics, Leiden, The Netherlands., Wintermans B; Department of Medical Microbiology, Adrz Hospital, Goes, The Netherlands., Budding AE; Inbiome, Amsterdam, Netherlands., Spaink HP; Institute of Biology, Leiden University, Leiden, The Netherlands., Medema MH; Institute of Biology, Leiden University, Leiden, The Netherlands.; Bioinformatics Group, Wageningen University, Wageningen, The Netherlands., van Wezel GP; Institute of Biology, Leiden University, Leiden, The Netherlands.; Department of Microbial Ecology, Netherlands Institute of Ecology, Wageningen, The Netherlands.

Publikováno v: Environmental microbiology [Environ Microbiol] 2024 Feb; Vol. 26 (2), pp. e16589.

FAIR High Content Screening in Bioimaging.

Autor: Hosseini R; Life Science Semantics, Leiden Institute of Advanced Computer Science, Leiden, The Netherlands., Vlasveld M; Drug Discovery and Safety, Cell Observatory, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., Willemse J; Cell Observatory, Institute of Biology Leiden, Leiden, The Netherlands., van de Water B; Drug Discovery and Safety, Cell Observatory, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., Le Dévédec SE; Drug Discovery and Safety, Cell Observatory, Leiden Academic Centre for Drug Research, Leiden, The Netherlands. s.e.ledevedec@lacdr.leidenuniv.nl., Wolstencroft KJ; Life Science Semantics, Leiden Institute of Advanced Computer Science, Leiden, The Netherlands. k.j.wolstencroft@liacs.leidenuniv.nl.

Publikováno v: Scientific data [Sci Data] 2023 Jul 17; Vol. 10 (1), pp. 462. Date of Electronic Publication: 2023 Jul 17.