Zobrazeno 1 - 10
of 474
pro vyhledávání: '"Joost J. Oppenheim"'
Autor:
Xiao-Qing Li, Takahiro Yamazaki, Tianzhen He, Md Masud Alam, Jia Liu, Anna L. Trivett, Baldur Sveinbjørnsson, Øystein Rekdal, Lorenzo Galluzzi, Joost J. Oppenheim, De Yang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
LTX-315 is a synthetic cationic oncolytic peptide with potent anticancer activity but limited toxicity for non-malignant cells. LTX-315 induces both immunogenic tumor cell death and generation of tumor-specific immune responses in multiple experiment
Externí odkaz:
https://doaj.org/article/38be6eb6a7bf4036a60a9ac668042e62
Autor:
Saifun Nahar, Yue Huang, Bethany A. Nagy, John A. Zebala, Dean Y. Maeda, Udo Rudloff, Joost J. Oppenheim, De Yang
Publikováno v:
Cancers, Vol 15, Iss 8, p 2366 (2023)
Triple-negative breast carcinoma (TNBC) is one of the most aggressive types of solid-organ cancers. While immune checkpoint blockade (ICB) therapy has significantly improved outcomes in certain types of solid-organ cancers, patients with immunologica
Externí odkaz:
https://doaj.org/article/4600d2147cc8400f86b543c770fbd88b
Autor:
Chang-Yu Chen, Satoshi Ueha, Yoshiro Ishiwata, Shoji Yokochi, De Yang, Joost J. Oppenheim, Haru Ogiwara, Shigeyuki Shichino, Shungo Deshimaru, Francis H. W. Shand, Shiro Shibayama, Kouji Matsushima
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Background Transient depletion of CD4+ T cells results in tumor suppression and survival benefit in murine models; however, the tumor progression and recurrence still occur over more long-term monitoring of mice. Thus, we explored an additio
Externí odkaz:
https://doaj.org/article/66c6295675c24b7c82a27034e116f967
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
High mobility group nucleosome-binding protein 1 (HMGN1 or N1) is a Th1-polarizing alarmin, but alone is insufficient to induce antitumor immunity. We previously showed that combination of N1 and R848, a synthetic TLR7/8 agonist, synergistically acti
Externí odkaz:
https://doaj.org/article/8fe47025adab4635a6f71aba37a37003
Autor:
Rob J. W. Arts, Po-Kai Huang, De Yang, Leo A. B. Joosten, Jos W. M. van der Meer, Joost J. Oppenheim, Mihai G. Netea, Shih-Chin Cheng
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
High-mobility group nucleosome-binding protein 1 (HMGN1) functions as a non-histone chromatin-binding protein in the cell nucleus. However, extracellular HMGN1 acts as an endogenous danger-associated inflammatory mediator (also called alarmin). We de
Externí odkaz:
https://doaj.org/article/ad0f6edde30f47c6808b2f025226051c
Autor:
Joost J. Oppenheim
Publikováno v:
Frontiers in Immunology, Vol 5 (2014)
N/A
Externí odkaz:
https://doaj.org/article/f2d650d200ab43e78ec7bbdf552f67e4
A Therapeutic Vaccine in Combination with Cyclic GMP–AMP Cures More Differentiated Melanomas in Mice
Publikováno v:
The Journal of Immunology. 210:1428-1436
We have identified a combinational immunotherapy termed TheraVac vaccine (TheraVac) that can cure multiple large established mouse tumors, but it failed to cure melanoma in mice. TheraVac consists of an immunostimulating arm containing an agonist (HM
Autor:
Tianzhen He, Yibo Chen, De Yang, Md Sahidul Islam, Chon-Kit Chou, Jiarui Liu, Denise L. Faustman, Joost J. Oppenheim, Xin Chen
Publikováno v:
Cellular Oncology. 46:167-177
Autor:
Albert Zlotnik, Osamu Yoshie, Mohib Uddin, Marcus Thelen, Alexander H. Sparre-Ulrich, Silvano Sozzani, Antal Rot, Mette M. Rosenkilde, Amanda E. I. Proudfoot, Christine A. Power, Joost J. Oppenheim, Hisayuki Nomiyama, Robert J. B. Nibbs, Philip M. Murphy, Georgios L. Moschovakis, Amy E. Monaghan, Kouji Matsushima, Alberto Mantovani, Andrew D. Luster, Massimo Locati, Richard Horuk, Rebecca Hills, Gerard J. Graham, Joshua M. Farber, Reinhold Förster, Christophe Combadiere, Israel F. Charo, Amanda M. Burkhardt, Adit Ben-Baruch, Francoise Bachelerie
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
Chemokine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Chemokine Receptors [438, 437, 32]) comprise a large subfamily of 7TM proteins that bind one or more chemokines, a large family of small cytokines typically possessing chemo
Autor:
Kouji Matsushima, Shiro Shibayama, Tatsuro Ogawa, Hiroyasu Aoki, Yuzuka Kanno, Shungo Deshimaru, Haru Ogiwara, Joost J. Oppenheim, De Yang, Shoji Yokochi, Shigeyuki Shichino, Yoshiro Ishiwata, Satoshi Ueha, Chang-Yu Chen
Supplementary Figures 1-5 and Supplementary table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57412bcc6d7812a93ce9b1841a5fc87f
https://doi.org/10.1158/2326-6066.22543263
https://doi.org/10.1158/2326-6066.22543263