Zobrazeno 1 - 10
of 1 933
pro vyhledávání: '"Joost H"'
Autor:
Jeron Venhuizen, Maaike G. J. M. van Bergen, Saskia M. Bergevoet, Daan Gilissen, Cornelia G. Spruijt, Laura Wingens, Emile van den Akker, Michiel Vermeulen, Joop H. Jansen, Joost H. A. Martens, Bert A. van der Reijden
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-9 (2024)
Abstract The transcription factor Growth Factor Independence 1B (GFI1B) recruits Lysine Specific Demethylase 1 A (LSD1/KDM1A) to stimulate gene programs relevant for megakaryocyte and platelet biology. Inherited pathogenic GFI1B variants result in th
Externí odkaz:
https://doaj.org/article/558fcbd9db0c4afb9f0c4bb2090de2b9
Autor:
Sergio Andreu‐Sánchez, Shahzad Ahmad, Alexander Kurilshikov, Marian Beekman, Mohsen Ghanbari, Martijn vanFaassen, Inge C. L. van denMunckhof, Marinka Steur, Amy Harms, Thomas Hankemeier, M. Arfan Ikram, Maryam Kavousi, Trudy Voortman, Robert Kraaij, Mihai G. Netea, Joost H. W. Rutten, Niels P. Riksen, Alexandra Zhernakova, Folkert Kuipers, P. Eline Slagboom, Cornelia M. vanDuijn, Jingyuan Fu, Dina Vojinovic
Publikováno v:
iMeta, Vol 3, Iss 3, Pp n/a-n/a (2024)
Abstract Trimethylamine N‐oxide (TMAO) is a circulating microbiome‐derived metabolite implicated in the development of atherosclerosis and cardiovascular disease (CVD). We investigated whether plasma levels of TMAO, its precursors (betaine, carni
Externí odkaz:
https://doaj.org/article/8f4a85a05abd4322a6397015b41442e1
Autor:
Amber H. van der Stam, Nienke M. de Vries, Sharon Shmuely, Daan Smeenk, Joost H. Rutten, Ineke A. van Rossum, Susanne T. de Bot, Jurgen A. Claassen, Bastiaan R. Bloem, Roland D. Thijs
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background In persons with Parkinson’s Disease (PD) or certain forms of atypical parkinsonism, orthostatic hypotension is common and disabling, yet often underrecognized and undertreated. About half of affected individuals also exhibit sup
Externí odkaz:
https://doaj.org/article/07d1877953ff43f98ab4c5339978e342
Autor:
Zhongli Chen, Robin P Peeters, Wesley Flach, Linda J de Rooij, Sena Yildiz, Alexander Teumer, Matthias Nauck, Rosalie B T M Sterenborg, Joost H W Rutten, Marco Medici, W Edward Visser, Marcel E Meima
Publikováno v:
European Thyroid Journal, Vol 12, Iss 4, Pp 1-11 (2023)
Objective: Thyroid hormone (TH) transport represents a critical first step in governing intracellular TH regulation. It is still unknown whether the full repertoire of TH transporters has been identified. Members of the solute carrier (SLC) 22 family
Externí odkaz:
https://doaj.org/article/2c1f801385674dea9938bb3ac518f358
Autor:
Helin Tercan, Benjamin C. Cossins, Rosanne C. van Deuren, Joost H. W. Rutten, Leo A. B. Joosten, Mihai G. Netea, Alexander Hoischen, Siroon Bekkering, Niels P. Riksen
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 2 (2024)
Background Obesity is accompanied by dysregulated inflammation, which can contribute to vasculometabolic complications including metabolic syndrome and atherosclerosis. Recently, clonal hematopoiesis of indeterminate potential (CHIP) has emerged as a
Externí odkaz:
https://doaj.org/article/386a3cf3b948494e8e35866013b4781d
Autor:
Marc J. T. Blaauw, Marvin A. H. Berrevoets, Wilhelm A. J. W. Vos, Albert L. Groenendijk, Louise E. van Eekeren, Nadira Vadaq, Gert Weijers, Andre J. A. M. van der Ven, Joost H. W. Rutten, Niels P. Riksen
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 20 (2023)
Background Cardiovascular disease is a major cause of morbidity and mortality in people living with HIV, who are at higher risk than the general population. We assessed, in a large cohort of people living with HIV, which cardiovascular, HIV‐specifi
Externí odkaz:
https://doaj.org/article/150cdec6de574f6cb04fb4d4d5ed8fc2
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Our current understanding of human hematopoiesis has undergone significant transformation throughout the years, challenging conventional views. The evolution of high-throughput technologies has enabled the accumulation of diverse data types, offering
Externí odkaz:
https://doaj.org/article/eabfe20a3f214ce48c24f11a3a7ae005
Autor:
Oscar G. Bos, Stephanie Duarte-Pedrosa, Karin Didderen, Joost H. Bergsma, Sonia Heye, Pauline Kamermans
Publikováno v:
Frontiers in Marine Science, Vol 10 (2023)
IntroductionThe European flat oyster (Ostrea edulis) is a biogenic reef former, internationally recognised as threatened and declining in the NE Atlantic by OSPAR and one of the focal species in nature inclusive designs in offshore windfarms in The N
Externí odkaz:
https://doaj.org/article/55a59d88c23c480582929c446de296d3
Autor:
Marwah Doestzada, Daria V. Zhernakova, Inge C. L. van den Munckhof, Daoming Wang, Alexander Kurilshikov, Lianmin Chen, Vincent W. Bloks, Martijn van Faassen, Joost H. W. Rutten, Leo A. B. Joosten, Mihai G. Netea, Cisca Wijmenga, Niels P. Riksen, Alexandra Zhernakova, Folkert Kuipers, Jingyuan Fu
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Background Branched-chain amino acids (BCAAs; valine, leucine, and isoleucine) are essential amino acids that are associated with an increased risk of cardiometabolic diseases (CMD). However, there are still only limited insights into potent
Externí odkaz:
https://doaj.org/article/6287de997c674451afb5910bbc9900d2
Autor:
Jason P. Wray, Elitza M. Deltcheva, Charlotta Boiers, Simon Е Richardson, Jyoti Bikram Chhetri, John Brown, Sladjana Gagrica, Yanping Guo, Anuradha Illendula, Joost H. A. Martens, Hendrik G. Stunnenberg, John H. Bushweller, Rachael Nimmo, Tariq Enver
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The ETV6-RUNX1 chimeric- and native RUNX1-responsive regulomes in paediatric B-acute lymphoblastic leukemia (B-ALL) remain to be characterized. Here, the authors reveal functional antagonism between the two transcription factors predominantly for the
Externí odkaz:
https://doaj.org/article/57a324404a3a49c69acb08a4d571d807