Výsledky vyhledávání - "Joost F.M. Lensen"

Reduction of anionic sites in the glomerular basement membrane by heparanase does not lead to proteinuria

Autor: L.P.W.J. van den Heuvel, Ronnie G. Wismans, T.H. van Kuppevelt, Angelique L.W.M.M. Rops, Joost F.M. Lensen, J. van der Vlag, Jo H. M. Berden, M.J.W. van den Hoven, Jin-Ping Li, Israel Vlodavsky, Tessa J.M. Wijnhoven, Henry B.P.M. Dijkman, Eyal Zcharia

Publikováno v: Kidney International. Supplement, 73, 278-87
Kidney International. Supplement, 73, 3, pp. 278-87

Contains fulltext : 71200.pdf (Publisher’s version ) (Open Access) Heparan sulfate in the glomerular basement membrane has been considered crucial for charge-selective filtration. In many proteinuric diseases, increased glomerular expression of hep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d27e01e71025541e6eb0b3fca01a2a

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Adult and paediatric patients with minimal change nephrotic syndrome show no major alterations in glomerular expression of sulphated heparan sulphate domains

Autor: Toin H. van Kuppevelt, Mabel J. van den Hoven, Joost F.M. Lensen, Marinka A.H. Bakker, Tessa J.M. Wijnhoven, Gerarda Navis, Leo A. H. Monnens, Johan van der Vlag, Lambert P. van den Heuvel, Jo H. M. Berden, Andrea B. Kramer, Jack F.M. Wetzels, Joyce Geelen, Angelique L.W.M.M. Rops

Publikováno v: Nephrology Dialysis Transplantation, 22(10), 2886-2893. Oxford University Press
Nephrology, Dialysis, Transplantation, 22, 10, pp. 2886-93
Nephrology, Dialysis, Transplantation, 22, 2886-93

Contains fulltext : 51758.pdf (Publisher’s version ) (Open Access) BACKGROUND: Minimal change nephrotic syndrome (MCNS) is the most frequent form of nephrotic syndrome in childhood. In the glomerular basement membrane (GBM) of adult patients with M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b0a22f9e346fd7b030155780700c0a
https://research.rug.nl/en/publications/7a4b466c-5c17-476d-83b7-f34b577748ec

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In vivo degradation of heparan sulfates in the glomerular basement membrane does not result in proteinuria

Autor: Ronnie G. Wismans, Ron A. Wevers, Jo H. M. Berden, Mohammed Lamrani, Joost F.M. Lensen, Tessa J.M. Wijnhoven, Johan van der Vlag, Angelique L.W.M.M. Rops, Leo A. H. Monnens, Lambert P. van den Heuvel, Toin H. van Kuppevelt

Publikováno v: Journal of the American Society of Nephrology, 18, 3, pp. 823-32
Journal of the American Society of Nephrology, 18, 823-32

Contains fulltext : 53032.pdf (Publisher’s version ) (Open Access) Heparan sulfates (HS) are long, unbranched, negatively charged polysaccharides that are bound to core proteins. HS in the glomerular basement membrane (GBM) is reported to be import

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::672ae7fde1f26baa8df16d9a90f1ca4d
https://doi.org/10.1681/asn.2006070692

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Selection and characterization of a unique phage display-derived antibody against dermatan sulfate

Autor: Mauro S. G. Pavão, Angelique L.W.M.M. Rops, A.H.M.S.M. van Kuppevelt, Tessa J.M. Wijnhoven, Joost F.M. Lensen, J. van der Vlag, Jo H. M. Berden, L.P.W.J. van den Heuvel, L.H. Kuik, Elly M. M. Versteeg, Theo Hafmans

Publikováno v: Matrix Biology, 25, 457-61
Matrix Biology, 25, 7, pp. 457-61

Contains fulltext : 49843.pdf (Publisher’s version ) (Closed access) Dermatan sulfate (DS) is a member of the glycosaminoglycan (GAG) family and is primarily located in the extracellular matrix. Using a modified phage display procedure, we selected

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87b2f78a75df5fafa3a887ce5b2b186e
https://doi.org/10.1016/j.matbio.2006.06.003

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Characterization of anticoagulant heparinoids by immunoprofiling

Autor: Els M.A. van de Westerlo, Jo H. M. Berden, Joost F.M. Lensen, Angelique L.W.M.M. Rops, Lambert P. van den Heuvel, Toin H. van Kuppevelt, Nicole C. Smits, Johan van der Vlag, Tessa J.M. Wijnhoven

Publikováno v: Glycoconjugate Journal, 25, 177-85
Glycoconjugate Journal, 25, 2, pp. 177-85
Glycoconjugate Journal

Contains fulltext : 69731.pdf (Publisher’s version ) (Closed access) Heparinoids are used in the clinic as anticoagulants. A specific pentasaccharide in heparinoids activates antithrombin III, resulting in inactivation of factor Xa and-when additio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca6059a3bc397d07490aaba2ccde008
http://hdl.handle.net/2066/69731

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Removal of heparan sulfate from the glomerular basement membrane blocks protein passage

Autor: Joost F.M. Lensen, Johan van der Vlag, Ronnie G. Wismans, Lambert P. van den Heuvel, Tessa J.M. Wijnhoven, Dirk Lefeber, Jo H. M. Berden, Angelique L.W.M.M. Rops, Toin H. van Kuppevelt

Publikováno v: Journal of the American Society of Nephrology, 18, 12, pp. 3119-27
Journal of the American Society of Nephrology, 18, 3119-27

Contains fulltext : 51552.pdf (Publisher’s version ) (Open Access) Heparan sulfate (HS) within the glomerular basement membrane (GBM) is thought to play a major role in the charge-selective properties of the glomerular capillary wall. Recent data,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d4308ec0c4c9b950f7eed852a06ca3
https://hdl.handle.net/2066/51552

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Expression of glomerular heparan sulphate domains in murine and human lupus nephritis

Autor: Lambert P. van den Heuvel, Joost F.M. Lensen, Johan van der Vlag, Jo H. M. Berden, Toin H. van Kuppevelt, Marinka A.H. Bakker, Mabel J. van den Hoven, Tessa J.M. Wijnhoven, Angelique L.W.M.M. Rops

Publikováno v: Nephrology, Dialysis, Transplantation, 22, 1891-902
Nephrology, Dialysis, Transplantation, 22, 7, pp. 1891-902

Contains fulltext : 51776.pdf (Publisher’s version ) (Open Access) BACKGROUND: Recently, we identified specific N- and 6-O-sulphated heparan sulphate (HS) domains on activated glomerular endothelial cells. In this study, we evaluated in lupus nephr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55f1eb7984fb7ac43a5f67ba012fcdbb
http://hdl.handle.net/2066/51776

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Syndecan-1 deficiency aggravates anti-glomerular basement membrane nephritis

Autor: M.J.W. van den Hoven, Joost F.M. Lensen, Martin Götte, J. van der Vlag, Jo H. M. Berden, Eric J. Steenbergen, L.P.W.J. van den Heuvel, A.H.M.S.M. van Kuppevelt, M.H. Baselmans, Tessa J.M. Wijnhoven, F. Cevikbas, Angelique L.W.M.M. Rops

Publikováno v: Kidney International. Supplement, 72, 1204-15
Kidney International. Supplement, 72, 10, pp. 1204-15

Contains fulltext : 52267.pdf (Publisher’s version ) (Closed access) During the heterologous phase of experimental anti-glomerular basement membrane (anti-GBM) nephritis, leukocyte influx peaks within hours, whereas albuminuria occurs within 1 day.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d65d64c28b6fca0c7d978cb92b0b2f13
http://hdl.handle.net/2066/52267

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Heparan sulfate on activated glomerular endothelial cells and exogenous heparinoids influence the rolling and adhesion of leucocytes

Autor: Cor Jacobs, Johan van der Vlag, Jo H. M. Berden, Peter C. M. Linssen, Jan B.M. Boezeman, Angelique L.W.M.M. Rops, Lambert P. van den Heuvel, Joost F.M. Lensen, Tessa J.M. Wijnhoven, Toin H. van Kuppevelt

Publikováno v: Nephrology, Dialysis, Transplantation, 22, 1070-7
Nephrology, Dialysis, Transplantation, 22, 4, pp. 1070-7

Contains fulltext : 53416.pdf (Publisher’s version ) (Open Access) BACKGROUND: Proliferative glomerulonephritides are characterized by the influx of leucocytes. Heparan sulfate (HS) plays an important role in the recruitment, rolling and firm adhes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0436ef19f102256358614281744ab860
http://hdl.handle.net/2066/53416

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