Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Joost C. B. M. Zomerdijk"'
Autor:
Joost C. B. M. Zomerdijk, L J Bou Malhab, Mark Larance, Dimitris P. Xirodimas, P G Smith, Aurélien Perrin, P-E Gleizes, Aymeric P. Bailly, M Nagala, Angus I. Lamond, Emmanuelle Pion, M-F O'Donohue
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2016, 35 (4), pp.415--426. ⟨10.1038/onc.2015.104⟩
Oncogene, Nature Publishing Group, 2016, 35 (4), pp.415--426. ⟨10.1038/onc.2015.104⟩
The ubiquitin-like molecule NEDD8 is essential for viability, growth and development, and is a potential target for therapeutic intervention. We found that the small molecule inhibitor of NEDDylation, MLN4924, alters the morphology and increases the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab3e9dbb1f351b140cae0d63088c6fde
https://doi.org/10.1038/onc.2015.104
https://doi.org/10.1038/onc.2015.104
Autor:
Kostya I. Panov, Tatiana B. Panova, Sheng-Chung Lee, Bertrand C-M Tan, Tom Owen-Hughes, Jackie Russell, Jens S. Andersen, Joost C. B. M. Zomerdijk, Joanna Birch
Publikováno v:
The EMBO Journal
Birch, J L, Tan, B C-M, Panov, K I, Panova, T B, Andersen, J S, Owen-Hughes, T A, Russell, J, Lee, S-C & Zomerdijk, J C B M 2009, ' FACT facilitates chromatin transcription by RNA polymerases I and III ', EMBO Journal, vol. 28, no. 7, pp. 854-865 . https://doi.org/10.1038/emboj.2009.33
Birch, J L, Tan, B C-M, Panov, K I, Panova, T B, Andersen, J S, Owen-Hughes, T A, Russell, J, Lee, S-C & Zomerdijk, J C B M 2009, ' FACT facilitates chromatin transcription by RNA polymerases I and III ', EMBO Journal, vol. 28, no. 7, pp. 854-865 . https://doi.org/10.1038/emboj.2009.33
Udgivelsesdato: 2009-Apr-8 Efficient transcription elongation from a chromatin template requires RNA polymerases (Pols) to negotiate nucleosomes. Our biochemical analyses demonstrate that RNA Pol I can transcribe through nucleosome templates and that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b14395d9f74b4db87758b444def45fc3
http://europepmc.org/articles/PMC2647773
http://europepmc.org/articles/PMC2647773
Autor:
Joanna Birch, Joost C. B. M. Zomerdijk
Publikováno v:
Biochemical Society Transactions. 36:619-624
Transcription of the major ribosomal RNAs by Pol I (RNA polymerase I) is a key determinant of ribosome biogenesis, driving cell growth and proliferation in eukaryotes. Hundreds of copies of rRNA genes are present in each cell, and there is evidence t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9473fbd781ee3d44d6d6122a67d5c8c
https://doi.org/10.1042/bst0360619
https://doi.org/10.1042/bst0360619
Autor:
Taciana Kasciukovic, Joost C. B. M. Zomerdijk, Tanya Panova, Julia J Gorski, Jackie Russell, Kostya I. Panov, Shalini Pathak
Publikováno v:
The EMBO Journal. 26:1560-1568
In mammalian RNA polymerase I transcription, SL1, an assembly of TBP and associated factors (TAFs), is essential for preinitiation complex formation at ribosomal RNA gene promoters in vitro. We provide evidence for a novel component of SL1, TAF(I)41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfa3a5a3c6ee90b85d203883b15434c0
https://doi.org/10.1038/sj.emboj.7601601
https://doi.org/10.1038/sj.emboj.7601601
Publikováno v:
Molecular and Cellular Biology. 26:5957-5968
Mammalian RNA polymerase I (Pol I) complexes contain a number of associated factors, some with undefined regulatory roles in transcription. We demonstrate that casein kinase 2 (CK2) in human cells is associated specifically only with the initiation-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36abe654236e0c5e9fd3d19876db92ef
https://doi.org/10.1128/mcb.00673-06
https://doi.org/10.1128/mcb.00673-06
Publikováno v:
The EMBO Journal. 25:3310-3322
Ribosomal RNA gene transcription by RNA polymerase I (Pol I) is the driving force behind ribosome biogenesis, vital to cell growth and proliferation. The key activator of Pol I transcription, UBF, has been proposed to act by facilitating recruitment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628e206c9b7223ecc0f243078d248eaa
https://doi.org/10.1038/sj.emboj.7601221
https://doi.org/10.1038/sj.emboj.7601221
Publikováno v:
Trends in Biochemical Sciences. 30:87-96
In the extensive network of interdependent biochemical processes required for cell growth and division, there is mounting evidence that ribosomal DNA transcription by RNA polymerase I (pol I) not only drives cell growth via its direct role in product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba5f2d8eb179ed4fc807bf0e0ef3f925
https://doi.org/10.1016/j.tibs.2004.12.008
https://doi.org/10.1016/j.tibs.2004.12.008
Publikováno v:
Science. 333:1640-1642
Transcription by eukaryotic RNA polymerases (Pols) II and III and archaeal Pol requires structurally related general transcription factors TFIIB, Brf1, and TFB, respectively, which are essential for polymerase recruitment and initiation events. A TFI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67beda31873282dc7edfdcec5a64837a
https://doi.org/10.1126/science.1207656
https://doi.org/10.1126/science.1207656
Autor:
Anton K. Raap, Anita Dirks-Mulder, Inês Chaves, Joost C. B. M. Zomerdijk, Piet Borst, Roeland W. Dirks
Publikováno v:
Proceedings of the National Academy of Sciences. 95:12328-12333
In Trypanosoma brucei , transcription by RNA polymerase II and 5′ capping of messenger RNA are uncoupled: a capped spliced leader is trans spliced to every RNA. This decoupling makes it possible to have protein-coding gene transcription driven by R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f82ed2ada58aa67a0557bf89a07db96
https://doi.org/10.1073/pnas.95.21.12328
https://doi.org/10.1073/pnas.95.21.12328
Publikováno v:
Proceedings of the National Academy of Sciences. 94:1733-1738
Promoter selectivity for all three classes of eukaryotic RNA polymerases is brought about by multimeric protein complexes containing TATA box binding protein (TBP) and specific TBP-associated factors (TAFs). Unlike class II- and III-specific TBP–TA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17f60b8b2ec86c9c8b1106ba247653cb
https://doi.org/10.1073/pnas.94.5.1733
https://doi.org/10.1073/pnas.94.5.1733