Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Joost Alexander Kolkman"'
Autor:
Judith Baumeister, Sandy Jacobs, Cedric Jozef Neotere Ververken, Joost Alexander Kolkman, Bert A. 't Hart, Hans Ulrichts, Michel P.M. Vierboom, Sofie Poelmans, Elia Breedveld, Maarten Van Roy, Sven Hoefman, Els Beirnaert, Lieselot Bontinck, Alex Hemeryck
Publikováno v:
Arthritis Research and Therapy, 17:135. BioMed Central Ltd.
Arthritis Research & Therapy
Arthritis Research & Therapy
Introduction The pleiotropic cytokine interleukin-6 (IL-6) plays an important role in the pathogenesis of different diseases, including rheumatoid arthritis (RA). ALX-0061 is a bispecific Nanobody® with a high affinity and potency for IL-6 receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f3ced2bf086f329611dd16a039053c
https://doi.org/10.1186/s13075-015-0651-0
https://doi.org/10.1186/s13075-015-0651-0
Autor:
Hilde Adi Pierrette Revets, Maria J.W.D. Vosjan, Marijke Stigter-van Walsum, Joost Alexander Kolkman, Jo Vercammen, Guus A.M.S. van Dongen
Publikováno v:
Vosjan, M J W D, Vercammen, J, Kolkman, J A, Stigter-van Walsum, M, Revets, H & van Dongen, G A M S 2012, ' Nanobodies Targeting the Hepatocyte Growth Factor: Potential New Drugs for Molecular Cancer Therapy ', Molecular Cancer Therapeutics, vol. 11, no. 4, pp. 1017-1025 . https://doi.org/10.1158/1535-7163.MCT-11-0891
Molecular Cancer Therapeutics, 11(4), 1017-1025. American Association for Cancer Research Inc.
Molecular Cancer Therapeutics, 11(4), 1017-1025. American Association for Cancer Research Inc.
Hepatocyte growth factor (HGF) and its receptor c-Met are associated with increased aggressiveness of tumors and poor prognostic outcome of patients with cancer. Here, we report the development and characterization of therapeutic anti-HGF (αHGF)-Nan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb623eb350919b80faf7f571b49db386
https://pubmed.ncbi.nlm.nih.gov/22319202
https://pubmed.ncbi.nlm.nih.gov/22319202