Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jooneon Park"'
Publikováno v:
Advanced Science, Vol 8, Iss 21, Pp n/a-n/a (2021)
Abstract Prognosis and treatment of metastatic cancer continues to be one of the most difficult and challenging areas of oncology. Treatment usually consists of chemotherapeutics, which may be ineffective due to drug resistance, adverse effects, and
Externí odkaz:
https://doaj.org/article/9ac3697f306b45afb9c1f8211e821138
Publikováno v:
Bioconjug Chem
Amine/thiol-reactive chemistries are commonly used to conjugate antibodies to pharmaceuticals or nanoparticles. Yet, these conjugation strategies often result in unfavorable outcomes such as heterogeneous antibody display with hindered biological act
Publikováno v:
Advanced Science
Advanced Science, Vol 8, Iss 21, Pp n/a-n/a (2021)
Advanced Science, Vol 8, Iss 21, Pp n/a-n/a (2021)
Prognosis and treatment of metastatic cancer continues to be one of the most difficult and challenging areas of oncology. Treatment usually consists of chemotherapeutics, which may be ineffective due to drug resistance, adverse effects, and dose‐li
Autor:
Yunmei Wang, Amy M. Wen, Daniel I. Simon, Jooneon Park, Matthew D Shin, Nicole F. Steinmetz, Huiyun Gao
Publikováno v:
Biomacromolecules
Thromboembolic conditions are a leading cause of death worldwide, and deep vein thrombosis (DVT), or occlusive venous clot formation, is a critical and rising problem that contributes to damage of vital organs, long-term complications, and life-threa
Publikováno v:
Journal of Materials Chemistry B. 7:1842-1846
We integrate a biocompatible plant virus-based nanotechnology (tobacco mosaic virus, TMV) with S100A9-targeting peptides for its application in imaging and diagnosis of atherosclerosis. S100A9-targeted TMV nanoparticles exhibit remarkable specificity
Publikováno v:
Cancer Research. 82:297-297
The current study investigates the use of an immunostimulatory plant virus nanoparticle called the cowpea mosaic virus (CPMV) in both the prophylaxis and treatment of metastatic breast cancer and melanoma. Metastatic cancer remains to this day one of
Autor:
Daniel I. Simon, He Hu, Jooneon Park, Huiyun Gao, Yunmei Wang, Nicole F. Steinmetz, Andrzej S. Pitek
Publikováno v:
Nanoscale. 10:16547-16555
Cardiovascular thrombotic disease is an underlying cause of stroke, myocardial infarction and pulmonary embolism - some of the leading causes of death worldwide. Reperfusion therapy with anticoagulant, antiplatelet, and fibrinolytic agents has signif
Publikováno v:
Expert Review of Molecular Diagnostics. 16:883-895
Nanoparticle-based disease diagnostics harness a range of unique physical and chemical phenomena for the detection of biomarkers at exceedingly low levels. This capability potentially enables the diagnosis of disease earlier in its progression and im
Autor:
Horst A. von Recum, Cian Desai, Leanna K. Robbins, Jooneon Park, Reza A. Ghiladi, Nicole F. Steinmetz, Lu Wang, Paul L. Chariou
Publikováno v:
Macromolecular bioscience. 19(5)
The development of plant viral nanoparticles (VNP) loaded with different molecular versions of a photodynamic drug is described. Specifically, tobacco mosaic virus (TMV) and tobacco mild green mosaic virus (TMGMV) are developed as drug carriers that
Publikováno v:
ACS applied materialsinterfaces. 9(23)
Magnetic particles are widely used as labels in magnetoresistive sensors. To use magnetic particles as labels, several important characteristics should be considered, such as superparamagnetism, a high magnetic moment per particle (m), facile surface