Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Joonatan, Mattila"'
Autor:
Joonatan Mattila, Silja Sormunen, Nelli Heikkilä, Ilkka P. Mattila, Jari Saramäki, T. Petteri Arstila
Publikováno v:
Cancer Medicine, Vol 12, Iss 12, Pp 13486-13496 (2023)
Abstract Background The number of mutations in cancer cells is an important predictor of a positive response to cancer immunotherapy. It has been suggested that the neoantigens produced by these mutations are more immunogenic than nonmutated tumor an
Externí odkaz:
https://doaj.org/article/a1fd196e9f9b4512b675514b1c392ed5
Autor:
Tuure Kinnunen, Silja Sormunen, Taina Härkönen, Jari Saramäki, Nelli Heikkilä, Emmi Leena Ihantola, Joonatan Mattila, Mikael Knip, Ilkka P. Mattila, T. Petteri Arstila
The T-cell receptor (TCR) repertoire is generated in a semistochastic process of gene recombination and pairing of TCRα to TCRβ chains with the estimated total TCR diversity of >108. Despite this high diversity, similar or identical TCR chains are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab24dfb9a0fddd727f3f10a8a28443a9
http://hdl.handle.net/10138/330936
http://hdl.handle.net/10138/330936
Publikováno v:
Scandinavian journal of immunology.
Thymic commitment of human FOXP3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5c5b2756c2318e9b00b787da9fe6efbc
https://pubmed.ncbi.nlm.nih.gov/29904934
https://pubmed.ncbi.nlm.nih.gov/29904934
Publikováno v:
Scandinavian Journal of Immunology. 88:e12681
Thymic commitment of human FOXP3+ regulatory T cells begins at the double positive (DP) CD4+ CD8+ stage. In the current study we show that interleukin-2 promotes the development of FOXP3+ thymocytes and enhances their survival at the DP phase. IL-2 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59bdd175c40d66f25188d6a347445a8c
https://doi.org/10.1111/sji.12681
https://doi.org/10.1111/sji.12681