Zobrazeno 1 - 10
of 340
pro vyhledávání: '"Joon-Yong Chung"'
Autor:
Jung-Hwan Baek, Myung Sup Kim, Hye Ryeon Jung, Min-Seon Hwang, Chan-ho Lee, Dai Hoon Han, Yong-ho Lee, Eugene C. Yi, Seung-Soon Im, Ilseon Hwang, Kyungeun Kim, Joon-Yong Chung, Kyung-Hee Chun
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 7, Pp 1520-1530 (2023)
Abstract Nonalcoholic fatty liver disease (NAFLD) occurs due to the accumulation of fat in the liver, leading to fatal liver diseases such as nonalcoholic steatohepatitis (NASH) and cirrhosis. Elucidation of the molecular mechanisms underlying NAFLD
Externí odkaz:
https://doaj.org/article/fa3fd4008685464f806a79d36788d5e5
Autor:
Se Jin Oh, Ji Yeon Lim, Min Kyu Son, Jun Hyeok Ahn, Kwon-Ho Song, Hyo-Jung Lee, Suyeon Kim, Eun Ho Cho, Joon-Yong Chung, Hanbyoul Cho, Hyosun Kim, Jae-Hoon Kim, Jooyoung Park, Jungmin Choi, Sun Wook Hwang, Tae Woo Kim
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Cisplatin resistance along with chemotherapy-induced neuropathic pain is an important cause of treatment failure for many cancer types and represents an unmet clinical need. Therefore, future studies should provide evidence regarding the mec
Externí odkaz:
https://doaj.org/article/06ccbeb755424a96a8f7e1fa1c9c1d40
Autor:
Razaul Haque, Jaebon Lee, Joon-Yong Chung, Ha-Yeon Shin, Hyosun Kim, Jae-Hoon Kim, Jae Won Yun, Eun-Suk Kang
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Background/objectiveHigh-grade serous ovarian carcinoma (HGSOC) is the most common histologic type of epithelial ovarian cancer (EOC). Due to its poor survival outcomes, it is essential to identify novel biomarkers and therapeutic targets. The hippo
Externí odkaz:
https://doaj.org/article/4f6c4656726a4cb78bcf21d804f94a55
Autor:
Sung Wook Son, Eunho Cho, Hanbyoul Cho, Seon Rang Woo, Hyo-Jung Lee, Se Jin Oh, Suyeon Kim, Jae-Hoon Kim, Eun Joo Chung, Joon-Yong Chung, Min Gyu Kim, Kwon-Ho Song, Tae Woo Kim
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Cancer immunoediting drives the adaptation of tumor cells to host immune surveillance. Previously, we have demonstrated that immunoediting driven by cytotoxic T lymphocytes (CTLs) enriches NANOG+ tumor cells with immune-refractory properties
Externí odkaz:
https://doaj.org/article/ba135651cfcf41238c5afc965403628b
Autor:
Ji-Won Ryu, Ha-Yeon Shin, Hyo-Sun Kim, Gwan Hee Han, Jeong Won Kim, Hae-Nam Lee, Hanbyoul Cho, Joon-Yong Chung, Jae-Hoon Kim
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Hormones may be key factors driving cancer development, and epidemiological findings suggest that steroid hormones play a crucial role in ovarian tumorigenesis. We demonstrated that high glucocorticoid receptor (GR) expression is associated with a po
Externí odkaz:
https://doaj.org/article/cb682db390244c7c9734721bc86f1e6e
Autor:
Kyung Mi Choi, Jeong Jin Kim, Jihye Yoo, Ku Sul Kim, Youngeun Gu, John Eom, Haengdueng Jeong, Kyungeun Kim, Ki Taek Nam, Young Soo Park, Joon-Yong Chung, Jun-Young Seo
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 24 (2022)
Metabolic reprogramming is an important cancer hallmark. However, the mechanisms driving metabolic phenotypes of cancer cells are unclear. Here, we show that the interferon-inducible (IFN-inducible) protein viperin drove metabolic alteration in cance
Externí odkaz:
https://doaj.org/article/1535c7948d144120b13aae0447d830f5
Autor:
Ha Kyun Chang, Young Hoon Park, Jung-A Choi, Jeong Won Kim, Jisup Kim, Hyo Sun Kim, Hae Nam Lee, Hanbyoul Cho, Joon-Yong Chung, Jae-Hoon Kim
Publikováno v:
Cancers, Vol 15, Iss 10, p 2865 (2023)
The adhesion molecule Nectin-4 is a new potential therapeutic target for different types of cancer; however, little is known about its diagnosis significance in endometrial cancer (EC). We found that Nectin-4 expression was significantly higher in EC
Externí odkaz:
https://doaj.org/article/9cd5548625734f5b80844443f8819b1b
Autor:
Ha‐Yeon Shin, Wookyeom Yang, Doo Byung Chay, Eun‐ju Lee, Joon‐Yong Chung, Hyun‐Soo Kim, Jae‐Hoon Kim
Publikováno v:
Molecular Oncology, Vol 15, Iss 4, Pp 987-1004 (2021)
Ovarian clear cell carcinoma (OCCC) reportedly develops from endometriosis. However, the molecular mechanism underlying its malignant progression to OCCC remains elusive. This study aimed to identify an essential gene in the malignant transformation
Externí odkaz:
https://doaj.org/article/d85ccfa3fbdb4d8c9521ceac735aa122
Autor:
Michael Andrews, Teruhiko Yoshida, Clark M Henderson, Hannah Pflaum, Ayako McGregor, Joshua A Lieberman, Ian H de Boer, Tomas Vaisar, Jonathan Himmelfarb, Bryan Kestenbaum, Joon-Yong Chung, Stephen M Hewitt, Briana A Santo, Brandon Ginley, Pinaki Sarder, Avi Z Rosenberg, Taichi Murakami, Jeffrey B Kopp, Zsuzsanna Kuklenyik, Andrew N Hoofnagle
Publikováno v:
PLoS ONE, Vol 17, Iss 10, p e0276649 (2022)
BackgroundGenetic variants in apolipoprotein L1 (APOL1), a protein that protects humans from infection with African trypanosomes, explain a substantial proportion of the excess risk of chronic kidney disease affecting individuals with sub-Saharan anc
Externí odkaz:
https://doaj.org/article/1ad117934bd2419bb2282f1e40dd23a2
Autor:
Shashi Shrivastav, Hewang Lee, Koji Okamoto, Huiyan Lu, Teruhiko Yoshida, Khun Zaw Latt, Hidefumi Wakashin, James L. T. Dalgleish, Erik H. Koritzinsky, Peng Xu, Laureano D. Asico, Joon-Yong Chung, Stephen Hewitt, John J. Gildea, Robin A. Felder, Pedro A. Jose, Avi Z. Rosenberg, Mark A. Knepper, Tomoshige Kino, Jeffrey B. Kopp
Publikováno v:
PLoS ONE, Vol 17, Iss 9 (2022)
HIV-associated nephropathy (HIVAN) impairs functions of both glomeruli and tubules. Attention has been previously focused on the HIVAN glomerulopathy. Tubular injury has drawn increased attention because sodium wasting is common in hospitalized HIV/A
Externí odkaz:
https://doaj.org/article/593f5764843b42f0b3ac93ffe4adecfb