Supplementary Figure 1 from Noncanonical Regulation of the Hedgehog Mediator GLI1 by c-MYC in Burkitt Lymphoma

Autor: David Walterhouse, Philip Iannaccone, Elizabeth Hyjek, Maria Proytcheva, Karl-Frederic Vieux, Stephen Iannaccone, Marilyn LG Lamm, Marisa Gallant, Joon Won Yoon

PDF file - 1257K, Supplemental Figure 1. Exposure of Burkitt lymphoma cells to SHH, IHH, or cyclopamine. (A). We do not detect changes in cell viability by MTT assay following exposure of BL1648, BL2625, or BL1647 cells to SHH peptide, or (B) cell vi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10115758ea108dc4b6dfb7c73e1ff605
https://doi.org/10.1158/1541-7786.22517419.v1

Supplementary Table 1 from Selective Down-Regulation of Glioma-Associated Oncogene 2 Inhibits the Proliferation of Hepatocellular Carcinoma Cells

Autor: Eric G. Marcusson, Brett P. Monia, Nicholas M. Dean, Xiaokun Xiao, Joon Won Yoon, Youngsoo Kim

Supplementary Table 1 from Selective Down-Regulation of Glioma-Associated Oncogene 2 Inhibits the Proliferation of Hepatocellular Carcinoma Cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f750666f7fca985f2c19654581decd3
https://doi.org/10.1158/0008-5472.22367790

Regulation of GLI1 by cis DNA elements and epigenetic marks

Autor: David J. Robbins, Robert L. Taylor, Kathrine B. Sylvestersen, Stephen Iannaccone, Ronnie Childs, King Fu Leong, Joon Won Yoon, David O. Walterhouse, Jun Long, Philip M. Iannaccone, Michael L. Nielsen

Publikováno v: Taylor, R, Long, J, Yoon, J W, Childs, R, Sylvestersen, K B, Nielsen, M L, Leong, K-F, Iannaccone, S, Walterhouse, D O, Robbins, D J & Iannaccone, P 2019, ' Regulation of GLI1 by cis DNA elements and epigenetic marks ', DNA Repair, vol. 79, pp. 10-21 . https://doi.org/10.1016/j.dnarep.2019.04.011
DNA repair

GLI1 is one of three transcription factors (GLI1, GLI2 and GLI3) that mediate the Hedgehog signal transduction pathway and play important roles in normal development. GLI1 and GLI2 form a positive-feedback loop and function as human oncogenes. The mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5f513f01ed19892e9a068d8432c2d4d
https://doi.org/10.1016/j.dnarep.2019.04.011

Sonic Hedgehog regulation of Foxf2 promotes cranial neural crest mesenchyme proliferation and is disrupted in cleft lip morphogenesis

Autor: Lydia J. Ansen-Wilson, Joon Won Yoon, Elizabeth J. Leslie, Mary L. Marazita, David O. Walterhouse, Joshua L. Everson, Hannah M. Chung, Robert J. Lipinski, Henry W. Kietzman, Dustin M. Fink

Publikováno v: Development.

Cleft lip is one of the most common human birth defects, yet our understanding of the mechanisms that regulate lip morphogenesis is limited. Here, we show that Sonic Hedgehog (Shh)-induced proliferation of cranial neural crest cell (cNCC) mesenchyme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b623c9bc3c8b52a81fc67a8d83fb63f1
https://doi.org/10.1242/dev.149930

Noncanonical Regulation of the Hedgehog Mediator GLI1 by c-MYC in Burkitt Lymphoma

Autor: Maria Proytcheva, Philip M. Iannaccone, Stephen Iannaccone, Karl Frederic Vieux, Elizabeth Hyjek, David O. Walterhouse, Marisa Gallant, Joon Won Yoon, Marilyn L. G. Lamm

Publikováno v: Molecular Cancer Research. 11:604-615

Although Hedgehog signaling plays a major role in GLI1 transcription, there is now evidence suggesting that other pathways/genes, such as c-MYC, may also regulate GLI1 expression. We initiated studies in Burkitt lymphoma cells, which constitutively e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e8f838276d1f301e9c70fde8dc32496
https://doi.org/10.1158/1541-7786.mcr-12-0441