Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Joon Won Park"'
Autor:
Ikbum Park, Hyun Jin Kim, Juyoung Shin, Yu Jin Jung, Donggyu Lee, Ji‐seon Lim, Jong Mok Park, Joon Won Park, Joung‐Hun Kim
Publikováno v:
Advanced Science, Vol 11, Iss 17, Pp n/a-n/a (2024)
Abstract The modification of synaptic and neural connections in adults, including the formation and removal of synapses, depends on activity‐dependent synaptic and structural plasticity. MicroRNAs (miRNAs) play crucial roles in regulating these cha
Externí odkaz:
https://doaj.org/article/19c2245a290f47ac876c2033fb433386
Publikováno v:
Sensors, Vol 10, Iss 1, Pp 428-455 (2010)
Vast numbers of studies and developments in the nanotechnology area have been conducted and many nanomaterials have been utilized to detect cancers at early stages. Nanomaterials have unique physical, optical and electrical properties that have prove
Externí odkaz:
https://doaj.org/article/06d58f61b79e4bb584ee81bff9097196
Autor:
Ju-Won Kwak, Hyobin Jeong, Sun-Ho Han, Youngkyu Kim, Sung Min Son, Inhee Mook-Jung, Daehee Hwang, Joon Won Park
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96456 (2014)
Monitoring protein phosphorylation at the cellular level is important to understand the intracellular signaling. Among the phosphoproteomics methods, phosphokinase antibody arrays have emerged as preferred tools to measure well-characterized phosphor
Externí odkaz:
https://doaj.org/article/86e219dd278a4450b64e40240402cf68
Publikováno v:
ACS Macro Letters. 12:421-427
Publikováno v:
Nano Letters. 22:3865-3871
Conventional methods for studying the spatial distribution and expression level of proteins within neurons have primarily relied on immunolabeling and/or signal amplification. Here, we present an atomic force microscopy (AFM)-based nanoscale force ma
Publikováno v:
Nano Letters. 22:1324-1330
Methylation changes at cytosine-guanine dinucleotide (CpG) sites in genes are closely related to cancer development. Thus, detection and quantification of low-abundance methylated DNA is critical for early diagnosis. Here, we report an atomic force m
Autor:
Ji Yoon Lee, Joon Won Park
Publikováno v:
The Analyst. 147:341-348
A convenient approach for obtaining fundamental constants such as affinity constant and dissociation constant at the single molecule level. The constants for the binding between dGTP and various cytosines in the polymerase pocket were compared.
Autor:
Myungshin Kim, Sang-Hyun Song, Yonggoo Kim, Changill Ban, Hayoung Choi, Sourav Mishra, Joon Won Park, Tae-You Kim, Jinseong Jeon, Jun-Kyu Kang
Publikováno v:
Nano Letters. 21:9061-9068
Cell-free DNA (cfDNA) analysis, specifically circulating tumor DNA (ctDNA) analysis, provides enormous opportunities for noninvasive early assessment of cancers. To date, PCR-based methods have led this field. However, the limited sensitivity/specifi
Publikováno v:
ACS omega. 7(23)
Proteins are key biomolecules that not only play various roles in the living body but also are used as biomarkers. If these proteins can be quantified at the level of a single cell, understanding the role of proteins will be deepened and diagnosing d
Autor:
Ji Yoon, Lee, Joon Won, Park
Publikováno v:
The Analyst. 147(2)
DNA methylation plays key roles in various areas, such as gene expression, regulation, epigenetics, and cancers. Since 5-methylcytosine (5mC) is commonly present in methylated DNA, characterizing the binding kinetics and thermodynamics of the nucleot