Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Joon Ho, Sa"'
Autor:
Hye Young Han, Jung A Lee, Hyeung-geun Park, Young Ah Shin, Shinae Kim, Jewon Yang, Jung Eun Lee, Yong Hyuk Kim, Joon Ho Sa, Hyun Joo Son, Jeeyeon Lee, Jae-Sun Kim, Je Ho Ryu
Publikováno v:
Journal of Medicinal Chemistry. 59:10176-10189
A series of picolinamide- and pyrimidine-4-carboxamide-based inhibitors of 11β-hydroxysteroid dehydrogenase type 1 was synthesized and evaluated to optimize the lead compound 9. The combination of the replacement of a pyridine ring of 9 with a pyrim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc435f3e1a9dc5cbbe84c5bd1226b06d
https://doi.org/10.1021/acs.jmedchem.6b01122
https://doi.org/10.1021/acs.jmedchem.6b01122
Autor:
Je Ho, Ryu, Jung A, Lee, Shinae, Kim, Young Ah, Shin, Jewon, Yang, Hye Young, Han, Hyun Joo, Son, Yong Hyuk, Kim, Joon Ho, Sa, Jae-Sun, Kim, Jungeun, Lee, Jeeyeon, Lee, Hyeung-Geun, Park
Publikováno v:
Journal of medicinal chemistry. 59(22)
A series of picolinamide- and pyrimidine-4-carboxamide-based inhibitors of 11β-hydroxysteroid dehydrogenase type 1 was synthesized and evaluated to optimize the lead compound 9. The combination of the replacement of a pyridine ring of 9 with a pyrim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3075207ab77c91082e48e767cab4e232
https://pubmed.ncbi.nlm.nih.gov/27798827
https://pubmed.ncbi.nlm.nih.gov/27798827
Autor:
Chang-Ik Choi, Seok-Yong Lee, Young Seo Park, Mi-Jeong Kim, Chang-Seon Myung, Jung-Woo Bae, Joon-Ho Sa, Yee Song, Choon-Gon Jang
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 31:2455-2466
This study was aimed to validate a reliable analytical method for the pharmacokinetic study of amiloride in human plasma by a high performance liquid chromatography (HPLC) system with UV detection. Triamterene was used as an internal standard. After
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b99601eb201d6b39823edfa3cf638c9d
https://doi.org/10.1080/10826070802319693
https://doi.org/10.1080/10826070802319693
Autor:
Su Sung Kim, Hyun Jung Lee, Joon Ho Sa, Kyeong-Hoon Jeong, Hyun Joo Son, Cheol Soo Choi, Hye Young Han, Shinae Kim, Hyunhee Oh, Hee-Sook Jun, Je Ho Ryu
Publikováno v:
European journal of pharmacology. 768
11β-Hydroxysteroid dehydrogenase type 1 (11βHSD1) has been targeted for new drugs to treat type 2 diabetes and metabolic syndrome. In this study, we determined whether the inhibition of 11βHSD1 with a new selective inhibitor, SKI2852, could improv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b1361734a158edee96e229a71d2e1d
https://pubmed.ncbi.nlm.nih.gov/26519792
https://pubmed.ncbi.nlm.nih.gov/26519792
Autor:
Seok-Yong Lee, Yun-Jeong Lee, Jung-Woo Bae, Hye-In Lee, Choon-Gon Jang, Chang-Ik Choi, Joon-Ho Sa
Publikováno v:
International journal of clinical pharmacology and therapeutics. 52(11)
Objective Pitavastatin, a highly potent inhibitor of 3-hydroxy-methylglutarylcoenzyme A reductase, is a known substrate of OATP1B1. Ursodeoxycholic acid (UDCA) inhibits OATP1B1 expression by repressing hepatocyte nuclear factor 1α (HNF1α). Thus, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b720931d3d7dcf4d29690e1a9a596346
https://pubmed.ncbi.nlm.nih.gov/25138679
https://pubmed.ncbi.nlm.nih.gov/25138679
Autor:
Myung, Chang-Seon1 (AUTHOR), Bae, Jung-Woo2 (AUTHOR), Park, Young-Seo3 (AUTHOR), Kim, Mi-Jeong2 (AUTHOR), Choi, Chang-Ik2 (AUTHOR), Song, Yee2 (AUTHOR), Sa, Joon-Ho2 (AUTHOR), Jang, Choon-Gon2 (AUTHOR), Lee, Seok-Yong2 (AUTHOR) sylee@skku.ac.kr
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 2008, Vol. 31 Issue 16, p2455-2466. 12p. 1 Diagram, 2 Charts, 3 Graphs.
Publikováno v:
British Journal of Clinical Pharmacology; Apr2011, Vol. 71 Issue 4, p550-555, 6p, 3 Charts, 2 Graphs
Publikováno v:
Clinical Pharmacology & Therapeutics; Apr2008, Vol. 83 Issue 4, p510-511, 2p, 8 Color Photographs