Zobrazeno 1 - 10
of 3 428
pro vyhledávání: '"Joon‐Yong An"'
Autor:
Soo-Whee Kim, Hyeji Lee, Da Yea Song, Gang-Hee Lee, Jungeun Ji, Jung Woo Park, Jae Hyun Han, Jee Won Lee, Hee Jung Byun, Ji Hyun Son, Ye Rim Kim, Yoojeong Lee, Jaewon Kim, Ashish Jung, Junehawk Lee, Eunha Kim, So Hyun Kim, Jeong Ho Lee, F. Kyle Satterstrom, Santhosh Girirajan, Anders D. Børglum, Jakob Grove, Eunjoon Kim, Donna M. Werling, Hee Jeong Yoo, Joon-Yong An
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-18 (2024)
Abstract Background Whole-genome sequencing (WGS) analyses have found higher genetic burden in autistic females compared to males, supporting higher liability threshold in females. However, genomic evidence of sex differences has been limited to Euro
Externí odkaz:
https://doaj.org/article/166c9e0cc2fe49d3a0572f9fa7e472de
Autor:
Kyeong-No Yoon, Sun Yong Kim, Jungeun Ji, Yidan Cui, Qing‐Ling Quan, Gunhyuk Park, Jang-Hee Oh, Ji Su Lee, Joon-Yong An, Jin Ho Chung, Yong-Seok Lee, Dong Hun Lee
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 6, Pp 1401-1411 (2024)
Abstract The effects of ultraviolet (UV) radiation on brain function have previously been investigated; however, the specific neurotransmitter-mediated mechanisms responsible for UV radiation-induced neurobehavioral changes remain elusive. In this st
Externí odkaz:
https://doaj.org/article/e6b536c20cb24bf4b24b68dc2c2d6d64
Autor:
Eunhyong Chang, Su‐Jung Kim, Hee Sang Hwang, Kyu Jin Song, Kwoneel Kim, Min‐Sik Kim, Se Jin Jang, Sungyong You, Kwang Pyo Kim, Joon‐Yong An
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 8, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/d03f14a36e114c7fb176e0bde48355a7
Autor:
Lee T. Kissel, Sirisha Pochareddy, Joon-Yong An, Nenad Sestan, Stephan J. Sanders, Xuran Wang, Donna M. Werling
Publikováno v:
Biological Psychiatry Global Open Science, Vol 4, Iss 4, Pp 100321- (2024)
Background: Sex-differential biology may contribute to the consistently male-biased prevalence of autism spectrum disorder (ASD). Gene expression differences between males and females in the brain can indicate possible molecular and cellular mechanis
Externí odkaz:
https://doaj.org/article/d733114370664bbfa9b5ddbb8c72e4f3
Autor:
Siavash Fazel Darbandi, Joon-Yong An, Kenneth Lim, Nicholas F. Page, Lindsay Liang, David M. Young, Athena R. Ypsilanti, Matthew W. State, Alex S. Nord, Stephan J. Sanders, John L.R. Rubenstein
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114329- (2024)
Summary: Many autism spectrum disorder (ASD)-associated genes act as transcriptional regulators (TRs). Chromatin immunoprecipitation sequencing (ChIP-seq) was used to identify the regulatory targets of ARID1B, BCL11A, FOXP1, TBR1, and TCF7L2, ASD-ass
Externí odkaz:
https://doaj.org/article/96b97b7930204f6ea8932076d915ef71
Autor:
Tomas Lagunas, Stephen P. Plassmeyer, Anthony D. Fischer, Ryan Z. Friedman, Michael A. Rieger, Din Selmanovic, Simona Sarafinovska, Yvette K. Sol, Michael J. Kasper, Stuart B. Fass, Alessandra F. Aguilar Lucero, Joon-Yong An, Stephan J. Sanders, Barak A. Cohen, Joseph D. Dougherty
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract The function of regulatory elements is highly dependent on the cellular context, and thus for understanding the function of elements associated with psychiatric diseases these would ideally be studied in neurons in a living brain. Massively
Externí odkaz:
https://doaj.org/article/1be3cfd23894463dbf386a6bfd6edefd
Autor:
Gaeun Park, Wooyoung Eric Jang, Seoyeon Kim, Edson Luck Gonzales, Jungeun Ji, Seunghwan Choi, Yujin Kim, Ji Hwan Park, Hazara Begum Mohammad, Geul Bang, Minkyung Kang, Soobin Kim, Se Jin Jeon, Jin Young Kim, Kwang Pyo Kim, Chan Young Shin, Joon-Yong An, Min-Sik Kim, Yong-Seok Lee
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 8, Pp 1783-1794 (2023)
Abstract Autism spectrum disorder (ASD) is a neurodevelopmental disorder associated with impaired social behavior and communication, repetitive behaviors, and restricted interests. In addition to genetic factors, environmental factors such as prenata
Externí odkaz:
https://doaj.org/article/c8519af411c745c6bc546c4f406e0f20
Autor:
Hee Jeong Yoo, Soowhee Kim, Jungeun Ji, Hyeji Lee, Ganghee Lee, Da-Yea Song, Jung Woo Park, Eunha Kim, Junehawk Lee, Jung Kyoon Choi, Jeong Ho Lee, Eunjoon Kim, Donna Werling, Joon-Yong An
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S149-S150 (2023)
Externí odkaz:
https://doaj.org/article/1dc61032fb714c95bce4b7898957cb4d
Autor:
Kyeong-No Yoon, Yujin Kim, Yidan Cui, Jungeun Ji, Gunhyuk Park, Jin Ho Chung, Yong-Seok Lee, Joon-Yong An, Dong Hun Lee
Publikováno v:
Molecular Brain, Vol 15, Iss 1, Pp 1-4 (2022)
Abstract Recent evidence indicates that ultraviolet (UV) exposure of the skin can affect brain functions such as learning and memory, addictive behavior, and hippocampal neurogenesis. These changes are closely associated with hippocampal function, wh
Externí odkaz:
https://doaj.org/article/f51b3e2888714205a916611c509d0612
Autor:
Lindsay Liang, Siavash Fazel Darbandi, Sirisha Pochareddy, Forrest O. Gulden, Michael C. Gilson, Brooke K. Sheppard, Atehsa Sahagun, Joon-Yong An, Donna M. Werling, John L. R. Rubenstein, Nenad Sestan, Kevin J. Bender, Stephan J. Sanders
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-14 (2021)
Abstract Background Genetic variants in the voltage-gated sodium channels SCN1A, SCN2A, SCN3A, and SCN8A are leading causes of epilepsy, developmental delay, and autism spectrum disorder. The mRNA splicing patterns of all four genes vary across devel
Externí odkaz:
https://doaj.org/article/7348d7aab02f4d87839686b6a126df57