Functional analysis of three putative galactofuranosyltransferases with redundant functions in galactofuranosylation in Aspergillus niger

Autor: Joohae Park, Ellen Lagendijk, Ebru Alazi, Arthur F. J. Ram, Cees A. M. J. J. van den Hondel, Davina de Lange, Mark Arentshorst

Publikováno v: Archives of Microbiology, 202(1), 197-203
Archives of Microbiology

Galactofuranose (Galf)-containing glycostructures are important to secure the integrity of the fungal cell wall. Golgi-localized Galf-transferases (Gfs) have been identified in Aspergillus nidulans and Aspergillus fumigatus. BLASTp searches identifie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ca79c49a7cefe2e61605f02a811b22
https://doi.org/10.1007/s00203-019-01709-w

Identification of SclB, a Zn(II)

Autor: Thomas R, Jørgensen, Anne-Marie, Burggraaf, Mark, Arentshorst, Tabea, Schutze, Gerda, Lamers, Jing, Niu, Min Jin, Kwon, Joohae, Park, Jens C, Frisvad, Kristian F, Nielsen, Vera, Meyer, Cees A M J J, van den Hondel, Paul S, Dyer, Arthur F J, Ram

Publikováno v: Fungal genetics and biology : FGB. 139

Certain Aspergillus species such as Aspergillus flavus and A. parasiticus are well known for the formation of sclerotia. These developmental structures are thought to act as survival structures during adverse environmental conditions but are also a p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::121399ffef7745f14d6fc7ef93577c08
https://pubmed.ncbi.nlm.nih.gov/32251730

Galactofuranose-Coated Gold Nanoparticles Elicit a Pro-inflammatory Response in Human Monocyte-Derived Dendritic Cells and Are Recognized by DC-SIGN

Autor: Joohae Park, Arthur F. J. Ram, Irma van Die, Soledad Penadés, Boris Tefsen, Fabrizio Chiodo, Marco Marradi

Publikováno v: Acs chemical biology, 9(2), 383-389. American Chemical Society
Chiodo, F, Marradi, M, Park, J, Ram, A F J, Penades, S, van Die, I & Tefsen, B 2014, ' Galactofuranose-Coated Gold Nanoparticles Elicit a Pro-inflammatory Response in Human Monocyte-Derived Dendritic Cells and Are Recognized by DC-SIGN ', Acs chemical biology, vol. 9, no. 2, pp. 383-389 . https://doi.org/10.1021/cb4008265

Galactofuranose (Galf) is the five-membered ring form of galactose exclusively found in nonmammalian species, among which several are pathogens. To determine the putative role of this carbohydrate in host-pathogen interactions, we synthesized multiva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9c1b5400b889c58c4e1a2acd4341c5d
https://doi.org/10.1021/cb4008265

Fungal alpha-arabinofuranosidases of glycosyl hydrolase families 51 and 54 show a dual arabinofuranosyl- and galactofuranosyl-hydrolyzing activity

Autor: Joohae Park, Boris Tefsen, Robert Winkler, Ellen Lagendijk, I.M. (Irma) van Die, Michiel Akeroyd, Doreen Schachtschabel, Arthur F. J. Ram

Publikováno v: Biological Chemistry
Biological Chemistry, 393(8), 767-775. Walter de Gruyter GmbH
Tefsen, B, Lagendijk, E L, Park, J, Akeroyd, M, Schachtschabel, D, Winkler, R, van Die, I M & Ram, A F J 2012, ' Fungal alpha-arabinofuranosidases of glycosyl hydrolase families 51 and 54 show a dual arabinofuranosyl-and galactofuranosyl-hydrolyzing activity ', Biological Chemistry, vol. 393, no. 8, pp. 767-775 . https://doi.org/10.1515/hsz-2012-0134
Biological Chemistry, 393(8), 767-775. De Gruyter

Aspergillus niger possesses a galactofuranosidase activity, however, the corresponding enzyme or gene encoding this enzyme has never been identified. As evidence is mounting that enzymes exist with affinity for both arabinofuranose and galactofuranos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a3348e3044249b44fe2c6e67e2d788
https://doi.org/10.1515/hsz-2012-0134

Additional file 1: Figure S1. of Identification and functional analysis of two Golgi-localized UDP-galactofuranose transporters with overlapping functions in Aspergillus niger

Autor: Joohae Park, Tefsen, Boris, Heemskerk, Marc, Lagendijk, Ellen, Hondel, Cees Van Den, Die, Irma Van, Ram, Arthur

Homology tree of UgtA and UgtB homologs in Aspergilli. Protein sequence homologous to A. niger UgtA or A. niger UgtB were extracted from the AspGD database and aligned using DNAman. % of amino acid identity is given. (PPTX 303 kb)

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