Zobrazeno 1 - 10
of 380
pro vyhledávání: '"JooHyuk Sohn"'
Autor:
Emi Noguchi, Takashi Yamanaka, Hirofumi Mukai, Naohito Yamamoto, Chi-Feng Chung, Yen-Shen Lu, Dwan-Ying Chang, Joohyuk Sohn, Gun Min Kim, Kyung-Hun Lee, Soo-Chin Lee, Tsutomu Iwasa, Hiroji Iwata, Kenichi Watanabe, Kyung Hae Jung, Yuko Tanabe, Seok Yun Kang, Hiroyuki Yasojima, Kenjiro Aogi, Eriko Tokunaga, Sung Hoon Sim, Yoon Sim Yap, Koji Matsumoto, Ling-Ming Tseng, Yoshiko Umeyama, Kazuki Sudo, Yuki Kojima, Tomomi Hata, Aya Kuchiba, Taro Shibata, Kenichi Nakamura, Yasuhiro Fujiwara, Kenji Tamura, Kan Yonemori
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract Palbociclib combined with endocrine therapy is approved for treating patients with hormone-receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2−) advanced breast cancer; however, data on palbociclib combined with t
Externí odkaz:
https://doaj.org/article/3cba658e7441401e9b9e50ad16a29171
Autor:
Sanghyun Park, Won-Ji Ryu, Tae Yeong Kim, Yumi Hwang, Hyun Ju Han, Jeong Dong Lee, Gun Min Kim, Joohyuk Sohn, Sang Kyum Kim, Min Hwan Kim, Joon Kim
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 4, Pp 987-1000 (2024)
Abstract Transcriptional programs governed by YAP play key roles in conferring resistance to various molecular-targeted anticancer agents. Strategies aimed at inhibiting YAP activity have garnered substantial interest as a means to overcome drug resi
Externí odkaz:
https://doaj.org/article/3db62ffb84a44c3ea216c7bf0d8d99a4
Autor:
Se-Young Jo, Jeong Dong Lee, Jeongsoo Won, Jiho Park, Taeyong Kweon, Seongyeon Jo, Joohyuk Sohn, Seung-Il Kim, Sangwoo Kim, Hyung Seok Park
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110469- (2024)
Summary: This study investigates the molecular characteristics and therapeutic implications of the BRCA1 L1780P mutation, a rare variant prevalent among Korean hereditary breast cancer patients. Using patient-derived xenograft (PDX) models and cell l
Externí odkaz:
https://doaj.org/article/a7d202b4e24a4751966166cfef8184bf
Autor:
Nar Bahadur Katuwal, Min Sil Kang, Mithun Ghosh, Sa Deok Hong, Yeong Gyu Jeong, Seong Min Park, Seul-Gi Kim, Joohyuk Sohn, Tae Hoen Kim, Yong Wha Moon
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-21 (2023)
Abstract Background Breast cancer is the global leading cancer burden in women and the hormone receptor-positive (HR+) subtype is a major part of breast cancer. Though cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors are highly effective therapy f
Externí odkaz:
https://doaj.org/article/d6b66fd44da1438f93bf7bcc8096c727
Autor:
Sun Kyung Baek, Jae-ho Jeong, KyungHae Jung, Hee Kyung Ahn, Min Hwan Kim, Joohyuk Sohn, In Hae Park, Jin Seok Ahn, Dae-Won Lee, Seock-Ah Im, Sung Hoon Sim, Keun Seok Lee, Jee Hyun Kim, Hyun-Jeong Shim, Yeesoo Chae, Su-Jin Koh, Hyorak Lee, Jieun Lee, Jae-Ho Byun, Youngmi Seol, Eun Mi Lee, Hee-Jung Jee, Hyonggin An, Eun Byeol Park, Young Ju Suh, Kyoung Eun Lee, Yeon Hee Park
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Purpose: This study aimed to investigate clinical practices and factors related to the outcomes of T-DM1 use in patients with HER2-positive metastatic breast cancer (mBC). Methods: We included patients with HER2-positive mBC who received T-DM1 as a p
Externí odkaz:
https://doaj.org/article/914a5337371a46a0a903edd08b8b34f9
Autor:
Jung Hwan Ji, Soong June Bae, Seul‐Gi Kim, Min Hwan Kim, Gun‐Min Kim, Joohyuk Sohn, Joon Jeong, Jee Hung Kim, Sung Gwe Ahn
Publikováno v:
Cancer Medicine, Vol 12, Iss 2, Pp 1409-1417 (2023)
Abstract Grade 3/4 anaemia, which is mainly induced by carboplatin, frequently occurs in patients treated with neoadjuvant docetaxel/carboplatin/trastuzumab/pertuzumab (TCHP). However, dose reduction of carboplatin may raise concerns about the oncolo
Externí odkaz:
https://doaj.org/article/36977867352a46bab6c51ccbc9befe28
Autor:
Chang Gon Kim, Min Hwan Kim, Jee Hung Kim, Seul-Gi Kim, Gun Min Kim, Tae Yeong Kim, Won-Ji Ryu, Jee Ye Kim, Hyung Seok Park, Seho Park, Young Up Cho, Byeong Woo Park, Seung Il Kim, Joon Jeong, Joohyuk Sohn
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-16 (2023)
Abstract Background Cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors have been established as a standard treatment for hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer (ABC); however,
Externí odkaz:
https://doaj.org/article/93318bd67f0041e39e14dac885e50ca8
Autor:
Sung Hoon Sim, Jeong Eun Kim, Min Hwan Kim, Yeon Hee Park, Jee Hyun Kim, Koung Jin Suh, Su-Jin Koh, Kyong Hwa Park, Myoung Joo Kang, Mi Sun Ahn, Kyoung Eun Lee, Hee-Jun Kim, Hee Kyung Ahn, Han Jo Kim, Keon Uk Park, Jae Ho Byun, Jin Hyun Park, Gyeong-Won Lee, Keun Seok Lee, Joohyuk Sohn, Kyung Hae Jung, In Hae Park
Publikováno v:
Breast, Vol 65, Iss , Pp 172-178 (2022)
We investigated the efficacy and safety of a trastuzumab biosimilar, Herzuma®, in combination with treatment of physician's choice (TPC) in patients with HER2+ metastatic breast cancer (MBC) who had failed at least two HER2 directed chemotherapies.
Externí odkaz:
https://doaj.org/article/330f949c2ee044c8b4039cf8ac994503
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Cognitive complaints after chemotherapy are common in breast cancer patients, but the neural bases for these complaints remain unclear. This pilot study explored resting-state functional connectivity (FC) as a marker of subtle cognitive chan
Externí odkaz:
https://doaj.org/article/bb1268496cff4f26bd392bceb3ce57a1
Autor:
Stephen Johnston, Joyce O’Shaughnessy, Miguel Martin, Jens Huober, Masakazu Toi, Joohyuk Sohn, Valérie A. M. André, Holly R. Martin, Molly C. Hardebeck, Matthew P. Goetz
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-5 (2021)
Abstract In MONARCH 3, continuous dosing of abemaciclib with an aromatase inhibitor (AI) conferred significant clinical benefit to postmenopausal women with HR+, HER2− advanced breast cancer. We report data for clinically prognostic subgroups: live
Externí odkaz:
https://doaj.org/article/cf9cf9b9d25d4a93984071353e442e17