Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Joo-Ho Shin"'
Autor:
Rin Khang, Areum Jo, Hojin Kang, Hanna Kim, Eunsang Kwag, Ji-Yeong Lee, Okjae Koo, Jinsu Park, Hark Kyun Kim, Dong-Gyu Jo, Inwoo Hwang, Jee-Yin Ahn, Yunjong Lee, Jeong-Yun Choi, Yun-Song Lee, Joo-Ho Shin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Although Krüppel-associated box domain-containing zinc-finger proteins (K-ZNFs) may be associated with sophisticated gene regulation in higher organisms, the physiological functions of most K-ZNFs remain unknown. The Zfp212 protein was high
Externí odkaz:
https://doaj.org/article/d066dbca80bf45fa93f045bb7639c08f
Autor:
Mina Yeom, Jin-Kyung Hong, Joo-Ho Shin, Yunjong Lee, Frederick Peter Guengerich, Jeong-Yun Choi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5198 (2023)
DNA polymerase (pol) η is responsible for error-free translesion DNA synthesis (TLS) opposite ultraviolet light (UV)-induced cis-syn cyclobutane thymine dimers (CTDs) and cisplatin-induced intrastrand guanine crosslinks. POLH deficiency causes one f
Externí odkaz:
https://doaj.org/article/fa5afcd5eeb247289d086477a709c710
Publikováno v:
Cells, Vol 11, Iss 22, p 3682 (2022)
Neuronal accumulation of parkin-interacting substrate (PARIS), a transcriptional repressor of peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α), has been observed in Parkinson’s disease (PD). Herein, we showed that PARI
Externí odkaz:
https://doaj.org/article/5d5a57d0fa48404d9abf983a1cb524b8
Autor:
Ga Ram Jeong, Eun-Hae Jang, Jae Ryul Bae, Soyoung Jun, Ho Chul Kang, Chi-Hu Park, Joo-Ho Shin, Yukio Yamamoto, Keiko Tanaka-Yamamoto, Valina L. Dawson, Ted M. Dawson, Eun-Mi Hur, Byoung Dae Lee
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-17 (2018)
Abstract Background Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of familial and sporadic Parkinson’s disease (PD). Elevated kinase activity is associated with LRRK2 toxicity, but the substrates that mediate neurodege
Externí odkaz:
https://doaj.org/article/82ef80fe0e5944a3bd82d33b19606f98
Autor:
Chun-Seob Ahn, Jeong-Geun Kim, Young-An Bae, Seon-Hee Kim, Joo-Ho Shin, Yichao Yang, Insug Kang, Yoon Kong
Publikováno v:
Parasites & Vectors, Vol 10, Iss 1, Pp 1-13 (2017)
Abstract Background Neurocysticercosis (NC) caused by Taenia solium metacestode (TsM) is a serious neurological disease of global concern. Diverse bioactive molecules involved in the long-term survival of TsM might contribute to disease progression.
Externí odkaz:
https://doaj.org/article/b16dcddb1fb34bc5b7b16351eaec8341
Autor:
Ji-Yeong Lee, Hanna Kim, Areum Jo, Rin Khang, Chi-Hu Park, Soo-Jeong Park, Eunsang Kwag, Joo-Ho Shin
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10, p 5392 (2021)
α-Synuclein (α-syn) is a hallmark amyloidogenic protein component of Lewy bodies in dopaminergic neurons affected by Parkinson’s disease (PD). Despite the multi-faceted gene regulation of α-syn in the nucleus, the mechanism underlying α-syn cro
Externí odkaz:
https://doaj.org/article/e7fd9a3b3a234b5492506433638c27fa
Autor:
Sangwoo Ham, Yun-Il Lee, Minkyung Jo, Hyojung Kim, Hojin Kang, Areum Jo, Gum Hwa Lee, Yun Jeong Mo, Sang Chul Park, Yun Song Lee, Joo-Ho Shin, Yunjong Lee
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Dysfunctional parkin due to mutations or post-translational modifications contributes to dopaminergic neurodegeneration in Parkinson’s disease (PD). Overexpression of parkin provides protection against cellular stresses and prevents dopami
Externí odkaz:
https://doaj.org/article/57f98ba85a7143c8bb7feb9bb5391a36
Autor:
Yunjong Lee, Daniel A. Stevens, Sung-Ung Kang, Haisong Jiang, Yun-Il Lee, Han Seok Ko, Leslie A. Scarffe, George E. Umanah, Hojin Kang, Sangwoo Ham, Tae-In Kam, Kathleen Allen, Saurav Brahmachari, Jungwoo Wren Kim, Stewart Neifert, Seung Pil Yun, Fabienne C. Fiesel, Wolfdieter Springer, Valina L. Dawson, Joo-Ho Shin, Ted M. Dawson
Publikováno v:
Cell Reports, Vol 18, Iss 4, Pp 918-932 (2017)
Mutations in PTEN-induced putative kinase 1 (PINK1) and parkin cause autosomal-recessive Parkinson’s disease through a common pathway involving mitochondrial quality control. Parkin inactivation leads to accumulation of the parkin interacting subst
Externí odkaz:
https://doaj.org/article/123875aada7941409485885b4db0fc67
Autor:
Ju-Yang Jung, Jin-Young Nam, Keun-Sil Ryu, In-Ok Son, Joo-Ho Shin, Wook-Young Baek, Hyoun-Ah Kim, Chang-Hee Suh
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3, p 1374 (2021)
We aimed to characterize the salivary protein components and identify biomarkers in patients with systemic lupus erythematosus (SLE). A proteomic analysis using two-dimensional gel electrophoresis and mass spectrometry was performed to determine the
Externí odkaz:
https://doaj.org/article/2538345236594ffe95eebf44a2351c8e
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 1, p 52 (2019)
The inactivation of parkin by mutation or post-translational modification contributes to dopaminergic neuronal death in Parkinson’s disease (PD). The substrates of parkin, FBP1 and AIMP2, are accumulated in the postmortem brains of PD patients, and
Externí odkaz:
https://doaj.org/article/721eb422155c4f51a73f7c51a6705f3b