Primary glia cells from bank vole propagate multiple rodent-adapted scrapie prions

Autor: Karla A. Schwenke, Joo-Hee Wälzlein, Agnieszka Bauer, Achim Thomzig, Michael Beekes

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)

Abstract Since the beginning prion research has been largely dependent on animal models for deciphering the disease, drug development or prion detection and quantification. Thereby, ethical as well as cost and labour-saving aspects call for alternati

Externí odkaz: https://doaj.org/article/75890684a65d44119a1311e6828b8d8b

3D

Autor: Sebastian, Schloer, Daniel, Treuherz, Aileen, Faist, Marlous, de Witt, Katharina, Wunderlich, Rainer, Wiewrodt, Karsten, Wiebe, Peter, Barth, Joo-Hee, Wälzlein, Susann, Kummer, Anne, Balkema-Buschmann, Stephan, Ludwig, Linda, Brunotte, Ursula, Rescher

Publikováno v: Emerging microbesinfections. 11(1)

Pandemic outbreaks of viruses such as influenza virus or SARS-CoV-2 are associated with high morbidity and mortality and thus pose a massive threat to global health and economics. Physiologically relevant models are needed to study the viral life cyc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bd3dcfcca1d6952d5aaa304d7457aeca
https://pubmed.ncbi.nlm.nih.gov/36000328

Glioblastoma-Induced Attraction of Endogenous Neural Precursor Cells Is Associated with Improved Survival

Autor: Darko Markovic, Jürgen C. W. Kiwit, Daniela Gast, Joo-Hee Wälzlein, Gerd Kempermann, Liping Wang, Golo Kronenberg, Michael Synowitz, Helmut Kettenmann, Rainer Glass

Publikováno v: 56. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie e.V. (DGNC), 3èmes journées françaises de Neurochirurgie (SFNC); 20050507-20050511; Strasbourg; DOCP169 /20050504/

Neural precursor cells contribute to adult neurogenesis and to limited attempts of brain repair after injury. Here we report that in a murine experimental glioblastoma model, endogenous neural precursors migrate from the subventricular zone toward th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a2e1a1dcf8e222c962eb3d28b4d67d5
https://doi.org/10.1523/jneurosci.5118-04.2005

Neural precursor cells induce cell-death of high-grade astrocytomas via stimulation of TRPV1

Autor: Gunnar Dittmar, Joo-Hee Wälzlein, Benjamin F. Cravatt, Vincenzo Di Marzo, Gary R. Lewin, Luciano De Petrocellis, Kristin Stock, Stefan Momma, Roberta Imperatore, Michael Synowitz, Stefania Petrosino, Vitali Matyash, Rainer Glass, Jitender Kumar, Sridhar Reddy Chirasani, Luigia Cristino, Ulf Gurok, Ewan St. John Smith, Ulrike A. Nuber, Peter Wend, Alessia Ligresti, Bettina Purfürst, Helmut Kettenmann

Publikováno v: Nature medicine (Online) (2012). doi:10.1038/nm.2827
info:cnr-pdr/source/autori:Stock K., Kumar J., Synowitz M., Petrosino S., Imperatore R., Smith ES., Wend P., Purfürst B., Nuber UA., Gurok U., Matyash V., Wälzlein JH., Chirasani SR., Dittmar G., Cravatt BF., Momma S., Lewin GR., Ligresti A., De Petrocellis L., Cristino L., Di Marzo V., Kettenmann H., Glass R./titolo:Neural precursor cells induce cell-death of high-grade astrocytomas via stimulation of TRPV1/doi:10.1038%2Fnm.2827/rivista:Nature medicine (Online)/anno:2012/pagina_da:/pagina_a:/intervallo_pagine:/volume
Nature medicine
18 (2012). doi:10.1038/nm.2827
info:cnr-pdr/source/autori:Stock K, Kumar J, Synowitz M, Petrosino S, Imperatore R, Smith ES, Wend P, Purfürst B, Nuber UA, Gurok U, Matyash V, Wälzlein JH, Chirasani SR, Dittmar G, Cravatt BF, Momma S, Lewin GR, Ligresti A, De Petrocellis L, Cristino L, Di Marzo V, Kettenmann H, Glass R./titolo:Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1./doi:10.1038%2Fnm.2827/rivista:Nature medicine (Print)/anno:2012/pagina_da:/pagina_a:/intervallo_pagine:/volume:18

Primary astrocytomas of grade 3 or 4 according to the classification system of the World Health Organization (high-grade astrocytomas or HGAs) are preponderant among adults and are almost invariably fatal despite the use of multimodal therapy. Here w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::690c0d91f9241e4a02376d02c737a5ba
https://publications.cnr.it/doc/188488

Abstract 215: Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1

Autor: Luigia Cristino, Ulf Gurok, Vitali Matyash, Joo-Hee Wälzlein, Helmut Kettenmann, Jitender Kumar, Gary R. Lewin, Alessia Ligresti, Vincenzo Di Marzo, Luciano De Petrocellis, Michael Synowitz, Stefan Momma, Benjamin F. Cravatt, Bettina Purfürst, Ulrike A. Nuber, Kristin Stock, Stefania Petrosino, Roberta Imperatore, Joerg C. Tonn, Gunnar Dittmar, Ewan St. John Smith, Peter Wend, Sridhar Reddy Chirasani, Rainer Glass

Publikováno v: Cancer Research. 73:215-215

Primary astrocytomas of grade 3 or 4 according to the classification system of the World Health Organization (high-grade astrocytomas or HGAs) are preponderant among adults and are almost invariably fatal despite the use of multimodal therapy. Here w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::86f83bbcfa895e87f9d18eb3f02986ce
https://doi.org/10.1158/1538-7445.am2013-215