Zobrazeno 1 - 10 of 48 pro vyhledávání: '"Joo Young Kang"'
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Akademický článek
Acetylation of UHRF1 Regulates Hemi-methylated DNA Binding and Maintenance of Genome-wide DNA Methylation
Autor: Ja Young Hahm, Jin Woo Park, Joo-Young Kang, Junyoung Park, Chul-Hong Kim, Ji-Young Kim, Nam-Chul Ha, Jung-Woong Kim, Sang-Beom Seo
Publikováno v: Cell Reports, Vol 32, Iss 4, Pp 107958- (2020)
Summary: UHRF1 is a key regulator in DNA methylation maintenance. It binds histone H3K9me2/3 and hemi-methylated DNA and recruits DNMT1 to DNA replication forks during S phase. However, the regulatory mechanism of hemi-methylated DNA binding activity
Externí odkaz: https://doaj.org/article/1be58757a774465fa72b462473a6401a
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7
The H3K4 methyltransferase SETD1A is required for proliferation of non-small cell lung cancer cells by promoting S-phase progression
Autor: Ja Young Hahm, Junyoung Park, Joo-Young Kang, Yusang Hwang, Sang-Beom Seo, Jin Woo Park, Kwon-Sik Park
Publikováno v: Biochemical and Biophysical Research Communications. 561:120-127
Epigenetic dysregulation has been strongly implicated in carcinogenesis and is one of the mechanisms that contribute to the development of lung cancer. Using genome-wide CRISPR/Cas9 library screening, we showed SET domain-containing protein 1A (SETD1
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85709953cb7b78697ee1ea7352e7e1fd
https://doi.org/10.1016/j.bbrc.2021.05.026
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8
Negative Regulation of Erythroid Differentiation via the CBX8-TRIM28 Axis
Autor: Hyun Jeong Kim, Jin Woo Park, Joo-Young Kang, Sang-Beom Seo
Publikováno v: Molecules and Cells
Although the mechanism of chronic myeloid leukemia (CML) initiation through BCR/ABL oncogene has been well characterized, CML cell differentiation into erythroid lineage cells remains poorly understood. Using CRISPR-Cas9 screening, we identify Chromo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98fef687b645d05d11b81dd9eda79821
http://europepmc.org/articles/PMC8334346
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