Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Joo Youn Park"'
Autor:
Carol L. Baker, Keun Seok Seo, Nogi Park, Jaime K. Rutter, Justin A. Thornton, Stephen B. Pruett, Joo Youn Park
Publikováno v:
mSphere, Vol 9, Iss 3 (2024)
ABSTRACTDiabetic foot ulcers (DFUs) are the most common complications of diabetes resulting from hyperglycemia leading to ischemic hypoxic tissue and nerve damage. Staphylococcus aureus is the most frequently isolated bacteria from DFUs and causes se
Externí odkaz:
https://doaj.org/article/867c3ead0c1549c6b173f490b9297832
Autor:
Yoonsung Hu, Nogi Park, Keun Seok Seo, Joo Youn Park, Radha P. Somarathne, Alicia K. Olivier, Nicholas C. Fitzkee, Justin A. Thornton
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 1841-1854 (2021)
Streptococcus pneumoniae (pneumococcus) is a normal colonizer of the human nasopharynx capable of causing serious invasive disease. Since colonization of the nasopharynx is a prerequisite for progression to invasive diseases, the development of futur
Externí odkaz:
https://doaj.org/article/04465f149de04617ba6d22de77e0a729
Autor:
Haider S. Manzer, Dustin T. Nguyen, Joo Youn Park, Nogi Park, Keun Seok Seo, Justin A. Thornton, Angela H. Nobbs, Kelly S. Doran
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT Streptococcus agalactiae, otherwise known as Group B Streptococcus (GBS), is an opportunistic pathogen that vaginally colonizes approximately one third of healthy women. During pregnancy, this can lead to in utero infection, resulting in pre
Externí odkaz:
https://doaj.org/article/10dbdd73b46149aa9f2e3a38da4f5bad
Autor:
Laxmi Dhungel, Lindsey Burcham, Joo Youn Park, Harshini Devi Sampathkumar, Albert Cudjoe, Keun Seok Seo, Heather Jordan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Buruli ulcer is a neglected tropical disease caused by the environmental pathogen, Mycobacterium ulcerans whose major virulence factor is mycolactone, a lipid cytotoxic molecule. Buruli ulcer has high morbidity, particularly in rural West Af
Externí odkaz:
https://doaj.org/article/134f63d65ecf4aeb974abd2cecf1853a
Autor:
Keun Seok Seo, Nogi Park, Jaime K. Rutter, Youngkyung Park, Carol L. Baker, Justin A. Thornton, Joo Youn Park
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 2 (2021)
ABSTRACT Diabetic foot ulcer (DFU) is the most common and costly sequela of diabetes mellitus, often leading to lower-extremity amputation with poor 5-year survival rates. Staphylococcus aureus is the most prevalent pathogen isolated from DFU, sugges
Externí odkaz:
https://doaj.org/article/fbb25a9e60aa4827b6e149422463a5fe
Autor:
Radha P. Somarathne, Emily R. Chappell, Y. Randika Perera, Rahul Yadav, Joo Youn Park, Nicholas C. Fitzkee
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Biofilms, when formed on medical devices, can cause malfunctions and reduce the efficiency of these devices, thus complicating treatments and serving as a source of infection. The autolysin protein of Staphylococcus epidermidis contributes to its bio
Externí odkaz:
https://doaj.org/article/3b689f88ce1b4196a06a3cda46b287b9
Autor:
Manouk Vrieling, Stephen W. Tuffs, Gonzalo Yebra, Marleen Y. van Smoorenburg, Joana Alves, Amy C. Pickering, Joo Youn Park, Nogi Park, David E. Heinrichs, Lindert Benedictus, Timothy Connelley, Keun Seok Seo, John K. McCormick, J. Ross Fitzgerald
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Staphylococcal superantigens (SAgs) are a family of secreted toxins that stimulate T cell activation and are associated with an array of diseases in humans and livestock. Most SAgs produced by Staphylococcus aureus are encoded by mobile gene
Externí odkaz:
https://doaj.org/article/1cc4076bef6448b7b578eeff51ccd2d1
Autor:
Bo Youn Moon, Joo Youn Park, D Ashley Robinson, Jonathan C Thomas, Yong Ho Park, Justin A Thornton, Keun Seok Seo
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151409 (2016)
The virulence of Staphylococcus aureus, in both human and animal hosts, is largely influenced by the acquisition of mobile genetic elements (MGEs). Most S. aureus strains carry a variety of MGEs, including three genomic islands (νSaα, νSaβ, νSa
Externí odkaz:
https://doaj.org/article/8017874c117449d1a28821d0fff4c6a7
Autor:
So Young Jang, Yoon Kyung Shin, So Young Park, Joo Youn Park, Seo-Hee Rha, Jong Kuk Kim, Hye Jeong Lee, Hwan Tae Park
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0116624 (2015)
Peripheral nerve myelination involves dynamic changes in Schwann cell morphology and membrane structure. Recent studies have demonstrated that autophagy regulates organelle biogenesis and plasma membrane dynamics. In the present study, we investigate
Externí odkaz:
https://doaj.org/article/4e72353b5ac148129ebe9f09f90ead1a
Autor:
Gillian J Wilson, Keun Seok Seo, Robyn A Cartwright, Timothy Connelley, Olivia N Chuang-Smith, Joseph A Merriman, Caitriona M Guinane, Joo Youn Park, Gregory A Bohach, Patrick M Schlievert, W Ivan Morrison, J Ross Fitzgerald
Publikováno v:
PLoS Pathogens, Vol 7, Iss 10, p e1002271 (2011)
Bacterial superantigens (SAg) stimulate T-cell hyper-activation resulting in immune modulation and severe systemic illnesses such as Staphylococcus aureus toxic shock syndrome. However, all known S. aureus SAgs are encoded by mobile genetic elements
Externí odkaz:
https://doaj.org/article/bd56f7a9b7594e6393143c69934225eb