Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Joo Seok Han"'
Autor:
Hyeongsun Jeong, Minwoo Wie, In-Joon Baek, Gyuwon Sohn, Si-Hyeon Um, Seon-Gyeong Lee, Yuri Seo, Jaesun Ra, Eun A Lee, Shinseog Kim, Byung Gyu Kim, Rajashree A. Deshpande, Tanya T. Paull, Joo Seok Han, Taejoon Kwon, Kyungjae Myung
Publikováno v:
Cells, Vol 11, Iss 24, p 4095 (2022)
Thyroid hormone receptor-interacting protein 13 (TRIP13) participates in various regulatory steps related to the cell cycle, such as the mitotic spindle assembly checkpoint and meiotic recombination, possibly by interacting with members of the HORMA
Externí odkaz:
https://doaj.org/article/4b2e977fd15442d1926016ad0d2944a2
Autor:
Dong Hyun Kim, Joo Seok Han, Peter Ly, Qiaozhen Ye, Moira A. McMahon, Kyungjae Myung, Kevin D. Corbett, Don W. Cleveland
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
The mitotic checkpoint complex (MCC) is assembled during both mitosis and interphase. Here, the authors use auxin-inducible degron tags to rapidly degrade TRIP13 and find that mitotic exit requires MCC disassembly by TRIP13-catalyzed removal of Mad2
Externí odkaz:
https://doaj.org/article/004fb7b590f04129989b8ca5e5d620a7
Autor:
Shuo-Chien Ling, Somasish Ghosh Dastidar, Seiya Tokunaga, Wan Yun Ho, Kenneth Lim, Hristelina Ilieva, Philippe A Parone, Sheue-Houy Tyan, Tsemay M Tse, Jer-Cherng Chang, Oleksandr Platoshyn, Ngoc B Bui, Anh Bui, Anne Vetto, Shuying Sun, Melissa McAlonis-Downes, Joo Seok Han, Debbie Swing, Katannya Kapeli, Gene W Yeo, Lino Tessarollo, Martin Marsala, Christopher E Shaw, Greg Tucker-Kellogg, Albert R La Spada, Clotilde Lagier-Tourenne, Sandrine Da Cruz, Don W Cleveland
Publikováno v:
eLife, Vol 8 (2019)
Mutations in coding and non-coding regions of FUS cause amyotrophic lateral sclerosis (ALS). The latter mutations may exert toxicity by increasing FUS accumulation. We show here that broad expression within the nervous system of wild-type or either o
Externí odkaz:
https://doaj.org/article/04213ee8809d4946acefc96cd36ba9b2
Autor:
Yejin Lee, Mi Ae Kang, Jong-Soo Lee, Kyungjae Myung, Soon Young Hwang, Jae-Hoon Jeong, Daechan Park, Joo Seok Han, Ngo Thanh Hang, Chul Joon Baik, Byung-Gyu Kim
Publikováno v:
Nucleic Acids Research
The pleiotropic CCCTC-binding factor (CTCF) plays a role in homologous recombination (HR) repair of DNA double-strand breaks (DSBs). However, the precise mechanistic role of CTCF in HR remains largely unclear. Here, we show that CTCF engages in DNA e
Autor:
Mi-Sun Kang, Hyun Ji Lee, Hongtae Kim, Yonghwan Kim, Joo Seok Han, Jae-Hoon Ji, Nam Soo Lee, Hae Ryung Chang, Kyungjae Myung, Joorak Lee, Yoojeong Seo, Soomi Kim
Publikováno v:
The Journal of Biological Chemistry
Cells have evolved sophisticated mechanisms to maintain genomic integrity in response to DNA damage. Ionizing radiation (IR)-induced DNA damage results in the formation of IR-induced foci (iRIF) in the nucleus. The iRIF formation is part of the DNA d
Autor:
Martin Marsala, Shuying Sun, Ngoc B. Bui, Tsemay M. Tse, Shuo-Chien Ling, Greg Tucker-Kellogg, Gene W. Yeo, Philippe A. Parone, Hristelina Ilieva, Seiya Tokunaga, Christopher Shaw, Sandrine Da Cruz, Oleksandr Platoshyn, Kenneth Lim, Somasish Ghosh Dastidar, Don W. Cleveland, Clotilde Lagier-Tourenne, Debbie Swing, Joo Seok Han, Albert R. La Spada, Anh Bui, Wan Yun Ho, Lino Tessarollo, Jer-Cherng Chang, Melissa McAlonis-Downes, Sheue-Houy Tyan, Anne P. Vetto, Katannya Kapeli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6336cbcf1decdbc907883e7a0b14a4f7
https://doi.org/10.7554/elife.40811.039
https://doi.org/10.7554/elife.40811.039
Autor:
Moira A. McMahon, Peter Ly, Dong Hyun Kim, Kevin D. Corbett, Don W. Cleveland, Joo Seok Han, Kyungjae Myung, Qiaozhen Ye
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature Communications
The mitotic checkpoint ensures accurate chromosome segregation through assembly of the mitotic checkpoint complex (MCC), a soluble inhibitor of the anaphase-promoting complex/cyclosome (APC/C) produced by unattached kinetochores. MCC is also assemble
Autor:
Kenneth Lim, Shuying Sun, Sandrine Da Cruz, Debbie Swing, Wan Yun Ho, Philippe A. Parone, Ngoc B. Bui, Jer Cherng Chang, Clotilde Lagier-Tourenne, Joo Seok Han, Albert R. La Spada, Hristelina Ilieva, Anh Bui, Melissa McAlonis-Downes, Katannya Kapeli, Don W. Cleveland, Seiya Tokunaga, Greg Tucker-Kellogg, Martin Marsala, Christopher Shaw, Oleksandr Platoshyn, Somasish Ghosh Dastidar, Tsemay M. Tse, Shuo-Chien Ling, Gene W. Yeo, Sheue Houy Tyan, Lino Tessarollo, Anne P. Vetto
Publikováno v:
Autophagy
eLife, Vol 8 (2019)
eLife
eLife, Vol 8 (2019)
eLife
Coding or non-coding mutations in FUS (fused in sarcoma) cause amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). In addition to familial ALS, abnormal aggregates of FUS are present in a portion of FTD and other neurodegenerative
Autor:
Joo Seok Han, Moira A. McMahon, Don W. Cleveland, Amira Abdullah, Daniele Fachinetti, Alex J. Wong, Peter Ly
Publikováno v:
Developmental cell, vol 33, iss 3
Summary Human centromeres are specified by a stably inherited epigenetic mark that maintains centromere position and function through a two-step mechanism relying on self-templating centromeric chromatin assembled with the histone H3 variant CENP-A,
Autor:
Philippe A. Parone, Don W. Cleveland, Sandrine Da Cruz, Anne P. Vetto, Joo Seok Han, Melissa McAlonis-Downes, Eva Tseng, Sandra K. Lee
Publikováno v:
The Journal of Neuroscience. 33:4657-4671
Mitochondria have been proposed as targets for toxicity in amyotrophic lateral sclerosis (ALS), a progressive, fatal adult-onset neurodegenerative disorder characterized by the selective loss of motor neurons. A decrease in the capacity of spinal cor