Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Joo Eun Jung"'
Autor:
Ryosuke Tashiro, Dan Ozaki, Jesus Bautista-Garrido, Guanghua Sun, Lidiya Obertas, Alexis S. Mobley, Gab Seok Kim, Jaroslaw Aronowski, Joo Eun Jung
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5187 (2023)
Aging drives cognitive decline, and mitochondrial dysfunction is a hallmark of age-induced neurodegeneration. Recently, we demonstrated that astrocytes secrete functional mitochondria (Mt), which help adjacent cells to resist damage and promote repai
Externí odkaz:
https://doaj.org/article/9387680c9438496bad463c1172598444
Autor:
Elisabeth Harmon, Andrea Doan, Jesus Bautista-Garrido, Joo Eun Jung, Sean P. Marrelli, Gab Seok Kim
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 16, p 8885 (2022)
Microglia, the resident innate immune cells of the brain, become more highly reactive with aging and diseased conditions. In collaboration with other cell types in brains, microglia can contribute both to worsened outcome following stroke or other ne
Externí odkaz:
https://doaj.org/article/f27a04058e8b4ac4a75a7ca3290f43ed
Autor:
Jee In Choi, Joo-Wan Choi, Kyu-Ho Shim, Jin Seung Choung, Hyun-Jin Kim, Hye Ryeong Sim, Mi Ri Suh, Joo Eun Jung, MinYoung Kim
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11995 (2021)
Our previous clinical studies demonstrated the synergistic therapeutic effect induced by co-administering recombinant human erythropoietin (rhEPO) in human umbilical cord blood (hUCB) therapy for children with cerebral palsy. However, the cellular me
Externí odkaz:
https://doaj.org/article/94f14bb0dc75484aab8d9060857bcb7f
Publikováno v:
Neurobiology of Disease, Vol 46, Iss 2, Pp 440-449 (2012)
Oxidative stress and glucose affect the expression of various genes that contribute to both reactive oxygen species generation and antioxidant systems. However, systemic alteration of oxidative stress-related gene expression in normal brains and in b
Externí odkaz:
https://doaj.org/article/bfbece36fab94949b6f6ad68fc6647e4
Autor:
Gab Seok Kim, Elisabeth Harmon, Manuel Gutierrez, Jessica Stephenson, Anjali Chauhan, Anik Banerjee, Zachary Wise, Andrea Doan, Ting Wu, Juneyoung Lee, Joo Eun Jung, Louise McCullough, Joshua Wythe, Sean Marrelli
Microglia are key mediators of inflammatory responses within the brain, as they regulate pro-inflammatory responses while also limiting neuroinflammation via reparative phagocytosis. Thus, identifying genes that modulate microglial function may revea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3b7ac832beff0f5e94f049bd861b931
https://doi.org/10.21203/rs.3.rs-2557290/v1
https://doi.org/10.21203/rs.3.rs-2557290/v1
Autor:
Elisabeth Harmon, Andrea Doan, Jesus Bautista-Garrido, Joo Eun Jung, Sean P Marrelli, Gab Seok Kim
Publikováno v:
Stroke. 54
Microglia (MG) play critical roles in modulating inflammation and interferon signaling is a driver of neuroinflammation in various neurodegenerative diseases. Recently, Ifitm3 (a member of the “interferon-inducible transmembrane” family) has been
Autor:
Ryosuke Tashiro, Jesus Bautista-Garrido, Dan Ozaki, Guanghua Sun, Lidiya Obertas, Alexis S Mobley, Gab Seok Kim, Jaroslaw Aronowski, Joo Eun Jung
Publikováno v:
J Neurosci
Astrocytes release functional mitochondria (Mt) that play regulatory and prosurvival functions on entering adjacent cells. We recently demonstrated that these released Mts could enter microglia to promote their reparative/prophagocytic phenotype that
Autor:
Alexis S Mobley, Ashley Hamlin, Jesus Bautista Garrido, Joo Eun Jung, Louise D McCullough, Jaroslaw Aronowski
Publikováno v:
The Journal of Immunology. 208:53.14-53.14
Aging affects immunologic responses by a global suppression of the immune system, including dysregulation of cytokine mediators, leading to increased inflammation throughout all systems, termed inflammaging. However, understanding mechanisms of healt
Autor:
Ryosuke Tashiro, Bautista-Garrido, Jesus, Ozaki, Dan, Guanghua Sun, Obertas, Lidiya, Mobley, Alexis S., Gab Seok Kim, Aronowski, Jaroslaw, Joo Eun Jung
Publikováno v:
Journal of Neuroscience; 9/7/2022, Vol. 42 Issue 36, p7001-7014, 14p
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
In a clinical trial of cerebral palsy, the level of plasma interleukin-8 (IL-8) was increased, correlated with motor improvement, after human umbilical cord blood mononuclear cell (hUCBC) infusion. This study aimed to elucidate the role of IL-8 in th