Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Joo‑ri Kim‑Kaneyama"'
Autor:
Masahito Noguchi, Aya Miyauchi, Yoshiaki Masaki, Masashi Sakaki, Xiao-Feng Lei, Momoko Kobayashi-Tanabe, Akira Miyazaki, Takeshi Aoki, Hitoshi Yoshida, Kohji Seio, Joo-ri Kim-Kaneyama
Publikováno v:
JHEP Reports, Vol 6, Iss 11, Pp 101195- (2024)
Background & Aims: Chronic liver diseases, including metabolic dysfunction-associated steatohepatitis (MASH), pose a significant global health burden. Progressive liver fibrosis can lead to severe outcomes; however, there is a lack of effective thera
Externí odkaz:
https://doaj.org/article/1d0608e23cbc477c9c612c92c8d63df7
Autor:
Aya Miyauchi, Masahito Noguchi, Xiao‑Feng Lei, Masashi Sakaki, Momoko Kobayashi‑Tanabe, Shogo Haraguchi, Akira Miyazaki, Joo‑ri Kim‑Kaneyama
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/78d0b053bc2944dbb242a3276c993bc4
Autor:
Aya Miyauchi, Masahito Noguchi, Xiao-Feng Lei, Masashi Sakaki, Momoko Kobayashi-Tanabe, Shogo Haraguchi, Akira Miyazaki, Joo-ri Kim-Kaneyama
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Osteoarthritis (OA) is the most common joint disease associated with articular cartilage destruction. Matrix metalloproteinase-13 (MMP-13) has an essential role in OA pathogenesis by degradation of collagen II, a major component of articular
Externí odkaz:
https://doaj.org/article/8028a36cdd6c4a79869db27613d87ad9
Autor:
Phuong Tran Pham, Oyunbileg Bavuu, Joo‐Ri Kim‐Kaneyama, Xiao‐Feng Lei, Takayuki Yamamoto, Kenichiro Otsuka, Kumiko Suto, Kenya Kusunose, Shusuke Yagi, Hirotsugu Yamada, Takeshi Soeki, Michio Shimabukuro, Glen N. Barber, Masataka Sata, Daiju Fukuda
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 22 (2023)
Background Sterile inflammation caused by metabolic disorders impairs endothelial function; however, the underlying mechanism by which hyperglycemia induces inflammation remains obscure. Recent studies have suggested that stimulator of interferon gen
Externí odkaz:
https://doaj.org/article/a6ac0ea28bf442d0ae024fb946f75ca7
Autor:
Song Ho Chang, Daisuke Mori, Hiroshi Kobayashi, Yoshifumi Mori, Hideki Nakamoto, Keita Okada, Yuki Taniguchi, Shurei Sugita, Fumiko Yano, Ung-il Chung, Joo-ri Kim-Kaneyama, Motoko Yanagita, Aris Economides, Ernesto Canalis, Di Chen, Sakae Tanaka, Taku Saito
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Excessive mechanical stress promotes the development of osteoarthritis. Here Chang et al. identify gremlin-1 as a factor expressed in chondrocytes in response to mechanical stress, and contributing to osteoarthritis via activation of the NF-κB pathw
Externí odkaz:
https://doaj.org/article/89ba19c2f9a9477294c478b865fc68cf
Autor:
Mitsuki Nozaki, Shogo Haraguchi, Takuro Miyazaki, Daichi Shigeta, Noriko Kano, Xiao-Feng Lei, Joo-ri Kim-Kaneyama, Hiroyuki Minakata, Akira Miyazaki, Kazuyoshi Tsutsui
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract The COS-7 (CV-1 in Origin with SV40 genes) cells are known as non-steroidogenic cells because they are derived from kidney cells and the kidney is defined as a non-steroidogenic organ. Therefore, COS-7 cells are used for transfection experim
Externí odkaz:
https://doaj.org/article/f340fed7abf444b58fe307574375f127
Autor:
Shogo Haraguchi, Masaki Kamata, Takuma Tokita, Kei-ichiro Tashiro, Miku Sato, Mitsuki Nozaki, Mayumi Okamoto-Katsuyama, Isao Shimizu, Guofeng Han, Vishwajit Sur Chowdhury, Xiao-Feng Lei, Takuro Miyazaki, Joo-ri Kim-Kaneyama, Tomoya Nakamachi, Kouhei Matsuda, Hirokazu Ohtaki, Toshinobu Tokumoto, Tetsuya Tachibana, Akira Miyazaki, Kazuyoshi Tsutsui
Publikováno v:
eLife, Vol 8 (2019)
The molecular mechanisms by which environmental light conditions affect cerebellar development are incompletely understood. We showed that circadian disruption by light-at-night induced Purkinje cell death through pineal allopregnanolone (ALLO) activ
Externí odkaz:
https://doaj.org/article/6d5dc4206ed54013a89ce2ae2cf2ab80
Autor:
Daiju Fukuda, Sachiko Nishimoto, Kunduziayi Aini, Atsushi Tanaka, Tsuyoshi Nishiguchi, Joo‐ri Kim‐Kaneyama, Xiao‐Feng Lei, Kiyoshi Masuda, Takuya Naruto, Kimie Tanaka, Yasutomi Higashikuni, Yoichiro Hirata, Shusuke Yagi, Kenya Kusunose, Hirotsugu Yamada, Takeshi Soeki, Issei Imoto, Takashi Akasaka, Michio Shimabukuro, Masataka Sata
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 7 (2019)
Background Toll‐like receptor (TLR) 9 recognizes bacterial DNA, activating innate immunity, whereas it also provokes inflammation in response to fragmented DNA released from mammalian cells. We investigated whether TLR9 contributes to the developme
Externí odkaz:
https://doaj.org/article/8f8f8329a3194984af6b247cbd40b84a
Autor:
Takuro Miyazaki, Yoshitaka Taketomi, Takayoshi Higashi, Hirokazu Ohtaki, Takashi Takaki, Koji Ohnishi, Masahiro Hosonuma, Nozomu Kono, Risako Akasu, Shogo Haraguchi, Joo-Ri Kim-Kaneyama, Kinya Otsu, Hiroyuki Arai, Makoto Murakami, Akira Miyazaki
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology.
Background: Although hypercholesterolemia reportedly counteracts lymphocyte trafficking across lymphatic vessels, the roles of lymphatic endothelial cells (LECs) in the lymphocyte regulations remain unclear. Previous studies showed that calpain—an
Autor:
Yeha Kim, Soyeon Lim, Taejeong Ha, You-Hyang Song, Young-In Sohn, Dae-Jin Park, Sun-Sook Paik, Joo-ri Kim-Kaneyama, Mi-Ryoung Song, Amanda Leung, Edward M Levine, In-Beom Kim, Yong Sook Goo, Seung-Hee Lee, Kyung Hwa Kang, Jin Woo Kim
Publikováno v:
eLife, Vol 6 (2017)
The visual responses of vertebrates are sensitive to the overall composition of retinal interneurons including amacrine cells, which tune the activity of the retinal circuitry. The expression of Paired-homeobox 6 (PAX6) is regulated by multiple cis-D
Externí odkaz:
https://doaj.org/article/f0f855a44e114ea1bbbebf0b3e7a55cf