Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jonian Grosha"'
Autor:
Daniel P. Salem, Laura T. Bortolin, Anthony D. Couvillon, Dan Gusenleitner, Jonian Grosha, Ibukunoluwapo O. Zabroski, Kelly M. Biette, Sanchari Banerjee, Christopher R. Sedlak, Delaney M. Byrne, Bilal F. Hamzeh, MacKenzie S. King, Lauren T. Cuoco, Peter A. Duff, Emily S. Winn-Deen, Eric K. Huang, Randy Schekman, Joseph C. Sedlak
Early detection of cancer remains a significant challenge. Existing liquid biopsy approaches to detect early-stage cancer show promise but suffer significant limitations including the abundance and stability of the analyte, large sample requirements,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35a437a40444ca5a2e6993ee1ac2b85b
https://doi.org/10.1101/2023.02.07.527360
https://doi.org/10.1101/2023.02.07.527360
Autor:
Daniel P. Salem, Laura T. Bortolin, Anthony D. Couvillon, Dan Gusenleitner, Jonian Grosha, Sanchari Banerjee, Kelly M. Biette, Ibukunoluwapo O. Zabroski, Christopher R. Sedlak, Delaney M. Byrne, Peter A. Duff, Bilal F. Hamzeh, MacKenzie S. King, Lauren T. Cuoco, Emily S. Winn-Deen, Eric K. Huang, Joseph C. Sedlak
Publikováno v:
Cancer Research. 83:3058-3058
Introduction: Extracellular vesicles (EVs) are abundant in biological fluids and increasingly recognized for their diagnostic and therapeutic potential. Unlike circulating tumor DNA which scales in abundance with tumor size and is a product of tumor
Autor:
Terri A. Camesano, Lindsay D. Lozeau, Marsha W. Rolle, Ian M Smith, Elizabeth J. Stewart, Jonian Grosha
Publikováno v:
ACS Biomaterials Science & Engineering. 6:3398-3410
Chronic infected wounds cause more than 23,000 deaths annually. Antibiotics and antiseptics are conventionally used to treat infected wounds; however, they can be toxic to mammalian cells, and their use can contribute to antimicrobial resistance. Ant
Autor:
Kathy Suqui, Marsha W. Rolle, Hannah A. Strobel, Gregory S. Fischer, Jonian Grosha, Christopher J. Nycz
Publikováno v:
Tissue Eng Part A
An essential step toward commercializing engineered tissues is to scale-up and automate their production. This presents a challenge for self-assembled tissues that are fragile at early time points and difficult to handle using robotic systems. The go
Autor:
Arlene H. Sharpe, Opeyemi Jegede, Megan Wind-Rotolo, Jean-Christophe Pignon, Robert J. Motzer, David A. Braun, Abdallah Flaifel, Sabina Signoretti, Jonian Grosha, Paul J. Catalano, Yuko Ishii, Michael B. Atkins, David F. McDermott, Toni K. Choueiri, Catherine J. Wu, Gordon J. Freeman, Sachet A. Shukla, F. Stephen Hodi, Kathleen M. Mahoney, Christine Horak, Jesse Novak
Publikováno v:
Clinical Cancer Research. 25:2174-2184
Purpose: Immune-related RECIST (irRECIST) were designed to capture atypical responses seen with immunotherapy. We hypothesized that, in patients with metastatic clear cell renal cell carcinoma (mccRCC), candidate biomarkers for nivolumab response wou
Autor:
Daniel P. Salem, Laura T. Bortolin, Sanchari Banerjee, Kelly M. Biette, Delaney M. Byrne, Anthony D. Couvillon, Peter A. Duff, Jonian Grosha, Daniel Gusenleitner, MacKenzie Sadie King, Christopher R. Sedlak, Ibukunoluwapo O. Zabroski, Karen Copeland, Emily S. Winn-Deen, Eric K. Huang, Christine D. Berg, Joseph C. Sedlak
Publikováno v:
Cancer Research. 82:2232-2232
Introduction: Screening for lung cancer (LC), the leading cause of cancer deaths, with helical computerized tomography lowers mortality but uptake is poor. Investigations into new approaches such as using circulating tumor cells and circulating tumor
Autor:
Laura T. Bortolin, Daniel P. Salem, Sanchari Banerjee, Kelly M. Biette, Delaney M. Byrne, Anthony D. Couvillon, Peter A. Duff, Jonian Grosha, MacKenzie Sadie King, Christopher R. Sedlak, Ibukunoluwapo O. Zabroski, Claire Alexander, Karen Copeland, Daniel Gusenleitner, Emily S. Winn-Deen, Eric K. Huang, Bo R. Rueda, Joseph Charles Sedlak
Publikováno v:
Cancer Research. 82:3390-3390
Introduction: Ovarian cancer (OC) is one of the deadliest cancers, with 314,000 new cases and 207,000 deaths globally in 2020. Serum CA125 has been explored as an OC biomarker for the past 40 years, but lacks sensitivity for early stage OC and is not
Autor:
Laura Bortolin, Daniel P. Salem, Jonian Grosha, Ibukunoluwapo O. Zabroski, Sanchari Banerjee, Daniel Gusenleitner, Kelly M. Biette, Christopher R. Sedlak, Anthony D. Couvillon, Peter A. Duff, Delaney M. Byrne, MacKenzie Sadie King, Amy Jamieson, Emily S. Winn-Deen, Jessica N. McAlpine, David Huntsman, Steven Skates, Eric K. Huang, Joseph Charles Sedlak
Publikováno v:
Journal of Clinical Oncology. 40:5542-5542
5542 Background: Detection of cancer with improved discrimination compared to current blood tests could be achieved using an approach that assesses extracellular vesicles (EVs). This approach should have high sensitivity (se) because of EVs abundance
Autor:
Jonian Grosha, Peter Kilbride, Marsha W. Rolle, Shannon Pasley, Claudia Zylberberg, Jun-Hung Cho
Publikováno v:
Cryobiology. 97:275
Autor:
Fioleda Prifti, Jonian Grosha, Terri A. Camesano, Denis Kole, Tanja Dominko, Marsha W. Rolle, Lindsay D. Lozeau
Publikováno v:
Acta biomaterialia. 52
Wound infections, particularly of chronic wounds, pose a substantial challenge for designing antimicrobial dressings that are both effective against pathogens, and do not interfere with wound healing. Due to their broad-spectrum antimicrobial and imm