Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Joni Lam"'
Autor:
Hailin Chen, Tengteng Yu, Liang Lin, Lijie Xing, Shih-Feng Cho, Kenneth Wen, Kimberly Aardalen, Adwait Oka, Joni Lam, Mike Daley, Haihui Lu, Nikhil Munshi, Kenneth C. Anderson, Yu-Tzu Tai
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 8, Pp 1-10 (2022)
Abstract We here defined the impacts of γ-secretase inhibitors (GSIs) on T-cell-dependent BCMA-specific multiple myeloma (MM) cell lysis and immunomodulatory effects induced by bispecific antibodies (BisAbs). GSIs-induced membrane BCMA (mBCMA) accum
Externí odkaz:
https://doaj.org/article/18630a073f974d81b53cefcf6ea2de9d
Autor:
Ryan D. Molony, Theresa Funk, Gina Trabucco, Erik Corcoran, David Ruddy, Malini Varadarajan, GiNell Elliot, Michelle Piquet, Joni Lam, Matthew J. Meyer, Hui Qin Wang, Sema Kurtulus, Haihui Lu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
CD3-engaging bispecific antibodies (BsAbs) enable the formation of an immune synapse between T cells and tumor cells, resulting in robust target cell killing not dependent on a preexisting tumor specific T cell receptor. While recent studies have she
Externí odkaz:
https://doaj.org/article/12e301bc91c748bb92eb9a21bd69d61e
Autor:
Hailin Chen, Tengteng Yu, Liang Lin, Lijie Xing, Shih-Feng Cho, Kenneth Wen, Kimberly Aardalen, Mike Daley, Haihui Lu, Adwait Oka, Joni Lam, Nikhil C Munshi, Kenneth C. Anderson, Yu-Tzu Tai
Publikováno v:
Blood. 140:9968-9969
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87511d81166b41b505726a92066d86a4
https://doi.org/10.1182/blood-2022-155553
https://doi.org/10.1182/blood-2022-155553
Autor:
Yu-Tzu Tai, Hailin Chen, Tengteng Yu, Liang Lin, Lijie Xing, Shih-Feng Cho, Kenneth Wen, Kimberly Aardalen, Adwait Oka, Joni Lam, Mike Daley, Haihui Lu, Nikhil Munshi, Kenneth Anderson
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 22:S5-S6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4a3634b88f73bbcd27a979298913130
https://doi.org/10.1016/s2152-2650(22)00282-8
https://doi.org/10.1016/s2152-2650(22)00282-8
Publikováno v:
Proceedings of the National Academy of Sciences. 101:12461-12466
Allosteric regulation of proteins by conformational change is a primary means of biological control. Traditionally it has been difficult to identify and characterize novel allosteric sites and ligands that freeze these conformational states. We prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1c1308b8e41c0875d4a052aef219cd0
https://doi.org/10.1073/pnas.0404781101
https://doi.org/10.1073/pnas.0404781101
Autor:
Shannon O. Harris, Stacey A. Heumann, Jeffrey W. Jacobs, William Michael Flanagan, Subramanian Baskaran, Kristin M. Zimmerman, Darin Allen, Minna Bui, Michael J. Romanowski, Bradley T. Tangonan, Johan D. Oslob, Robert S. McDowell, Wang Shen, Chris E Lawrence, Juli N. Teague, Willard Lew, Michelle M. Sopko, Michelle A. Nannini, Jeffrey A. Silverman, Joshua C. Yoburn, Chul Yu, Min Zhong, Hanan Emily, Ute Hoch, Amy D. Fung, Joni Lam, Robert A. Elling, Thomas O'Brien
Publikováno v:
Bioorganicmedicinal chemistry letters. 18(17)
This communication describes the discovery of a novel series of Aurora kinase inhibitors. Key SAR and critical binding elements are discussed. Some of the more advanced analogues potently inhibit cellular proliferation and induce phenotypes consisten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6628e44d37788613c268d76ba8583b8
https://pubmed.ncbi.nlm.nih.gov/18678489
https://pubmed.ncbi.nlm.nih.gov/18678489
Autor:
Chen, Hailin, Yu, Tengteng, Lin, Liang, Xing, Lijie, Cho, Shih-Feng, Wen, Kenneth, Aardalen, Kimberly, Oka, Adwait, Lam, Joni, Daley, Mike, Lu, Haihui, Munshi, Nikhil, Anderson, Kenneth C., Tai, Yu-Tzu
Publikováno v:
Blood Cancer Journal; Aug2022, Vol. 12 Issue 8, p1-10, 10p
Publikováno v:
Applied Cognitive Psychology. Mar2020, Vol. 34 Issue 2, p559-560. 2p.