Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jongtae Yang"'
Publikováno v:
Cancer Research. 83:4781-4781
Cell health and stress readouts are critical indicators of altered or impaired function in normal and diseased states of cells, and work has been underway to develop improved small molecule sensor dyes compatible with traditional imaging and High Con
Publikováno v:
Free Radical Biology and Medicine. 192:140-141
PicoGreen is a fluorescent probe that binds dsDNA and forms a highly luminescent complex when compared to the free dye in solution. This unique probe is widely used in DNA quantitation assays but has limited application in flow cytometry and microsco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1f1eda3861fb9290b53ecd4cb876fc3
Autor:
Aaron Janowsky, Michael K. Riscoe, Jongtae Yang, Martin J. Smilkstein, T. Mark Zabriskie, Katherine M. Wolfrum, Amy J. Eshleman, David J. Hinrichs, Robert A. Johnson
Publikováno v:
Psychopharmacology. 231:2771-2783
Mefloquine is used for the prevention and treatment of chloroquine-resistant malaria, but its use is associated with nightmares, hallucinations, and exacerbation of symptoms of post-traumatic stress disorder. We hypothesized that potential mechanisms
Publikováno v:
Journal of the American Chemical Society. 133:12124-12135
Glycosyltransferases are ubiquitous in nature. They catalyze a glycosidic bond formation between sugar donors and sugar or non-sugar acceptors to produce oligo/polysaccharides, glycoproteins, glycolipids, glycosylated natural products, and other suga
Publikováno v:
Org. Biomol. Chem.. 9:438-449
Validamycin A is a member of microbial-derived C(7)N-aminocyclitol family of natural products that is widely used as crop protectant and the precursor of the antidiabetic drug voglibose. Its biosynthetic gene clusters have been identified in several
Autor:
Dwi Andreas Santosa, Philip J. Proteau, T. Mark Zabriskie, Serge Fotso, Jongtae Yang, Taifo Mahmud, Rasti Saraswati
Publikováno v:
Journal of Natural Products. 73:472-475
Fractionation of the extract from the Indonesian Streptomyces sp. ICBB8198 as directed by the antibacterial activity delivered the known phenazine antibiotics griseoluteic acid (1a) and griseolutein A (1b), as well as two new phenazine derivatives (2
Autor:
James D. White, Jongtae Yang
Publikováno v:
Synlett. 2009:1713-1729
Biomimetic and other strategies that have been developed in theauthor’s laboratory for the synthesis of a subset of the groupof enzymically oxidized lipids known as oxylipins are described.This set of oxylipins contains both a cyclopropane and a la
Publikováno v:
Chemistry & Biology. 16:567-576
Summary Gene valD , encodes a large vicinal oxygen chelate (VOC) superfamily protein, has been identified in the validamycin biosynthetic gene cluster. Inactivation of valD significantly reduced validamycin A production, which was fully restored with
Publikováno v:
Applied Microbiology and Biotechnology. 81:895-902
The antifungal agent validamycin A is an important crop protectant and the source of valienamine, the precursor of the antidiabetic drug voglibose. Inactivation of the valN gene in the validamycin A producer, Streptomyces hygroscopicus subsp. jinggan