Výsledky vyhledávání - "Jongsma, H. J."

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Gap junction protein Cx37 interacts with endothelial nitric oxide synthase in endothelial cells

Autor: Pfenniger Anna, Derouette Jean-Paul, Verma Vandana, Lin Xianming, Foglia Bernard, Coombs Wanda, Roth Isabelle, Satta Nathalie, Dunoyer-Geindre Sylvie, Sorgen Paul, Taffet Steven, Kwak Brenda R, Delmar Mario, Miquerol L, Deutsch U, Jongsma H J, Chanson M, Kwak B R

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 30, No 4 (2010) pp. 827-834
Arteriosclerosis thrombosis and vascular biology

Objective— The gap junction protein connexin37 (Cx37) plays an important role in cell-cell communication in the vasculature. A C1019T Cx37 gene polymorphism, encoding a P319S substitution in the regulatory C terminus of Cx37 (Cx37CT), correlates wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1624a274f44b7e22f224da2ff1ea695
https://archive-ouverte.unige.ch/unige:20658

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Impaired conduction in the bundle branches of mouse hearts lacking the gap junction protein connexin40

Autor: van Rijen, H. V., van Veen, T. A., van Kempen, M. J., Wilms-Schopman, F. J., Potse, M., Krueger, O., Willecke, K., Opthof, T., Jongsma, H. J., de Bakker, J. M.

Publikováno v: Circulation, 103(11), 1591-1598. Lippincott Williams and Wilkins

Connexin (Cx)40 and Cx45 are the major protein subunits of gap junction channels in the conduction system of mammals. To determine the role of Cx40, we correlated cardiac activation with Connexin distribution in normal and Cx40-deficient mice hearts.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::905643064abe1ff7aec7dac0a15d0f89
https://pure.amc.nl/en/publications/impaired-conduction-in-the-bundle-branches-of-mouse-hearts-lacking-the-gap-junction-protein-connexin40(7980cbf5-9275-463a-97c1-faaf269012bf).html

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Propagation of the cardiac action potential from an ectopic focus into a two-dimensional sheet of ventricular cells

Autor: Wilders, R., Golod, D. A., Wagner, M. B., Kumar, R., Wang, Y. G., Goolsby, W. N., Joyner, L. W., Jongsma, H. J.

Publikováno v: Annual International Conference of the IEEE Engineering in Medicine and Biology-Proceedings

We have carried out computer simulations in which a model of an ectopic focus is incorporated as the central element of a two-dimensional sheet of ventricular cells in which the coupling conductances may be different in the X and Y directions and a s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::0e038d0be4e37366bb82fd6b22b908ff
https://pure.amc.nl/en/publications/propagation-of-the-cardiac-action-potential-from-an-ectopic-focus-into-a-twodimensional-sheet-of-ventricular-cells(c68304a7-18c6-4489-85d6-8c6bf1c80600).html

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Effects of ischemia on discontinuous action potential conduction in hybrid pairs of ventricular cells

Autor: Wilders, R., Verheijck, E. E., Joyner, R. W., Golod, D. A., Kumar, R., van Ginneken, A. C., Bouman, L. N., Jongsma, H. J.

Publikováno v: Circulation, 99(12), 1623-1629. Lippincott Williams and Wilkins

BACKGROUND: Acute ischemia often occurs in cardiac tissue that has prior injury, resulting in spatially inhomogeneous distributions of membrane properties and intercellular coupling. Changes in action potential conduction with ischemia, which can be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::0ebd6150e828f05a4b542200407e0a39
https://pure.amc.nl/en/publications/effects-of-ischemia-on-discontinuous-action-potential-conduction-in-hybrid-pairs-of-ventricular-cells(fc15177f-c69d-4381-9271-9d2b3eb4cc8b).html

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Electrical interactions between a rabbit atrial cell and a nodal cell model

Autor: Joyner, R. W., Kumar, R., Golod, D. A., Wilders, R., Jongsma, H. J., Verheijck, E. E., Bouman, L., Goolsby, W. N., van Ginneken, A. C.

Publikováno v: American journal of physiology, 274(6 Part 2), H2152-H2162. American Physiological Society

Atrial activation involves interactions between cells with automaticity and slow-response action potentials with cells that are intrinsically quiescent with fast-response action potentials. Understanding normal and abnormal atrial activity requires a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::d125ff5d74834449cbff40aeec374804
https://pure.amc.nl/en/publications/electrical-interactions-between-a-rabbit-atrial-cell-and-a-nodal-cell-model(97ba2cde-4d40-4a4d-9e5b-0b089bd23f68).html

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Gap junctions in human umbilical cord endothelial cells contain multiple connexins

Autor: van Rijen, H., van Kempen, M. J., Analbers, L. J., Rook, M. B., van Ginneken, A. C., Gros, D., Jongsma, H. J.

Publikováno v: American journal of physiology, 272(1 Part 1), C117-C130. American Physiological Society

We investigated the expression pattern of gap junctional proteins (connexins, Cx) in situ and in vitro and their functional characteristics in cultured human umbilical vein endothelial cells (HUVEC) and cultured human umbilical artery endothelial cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::d91631a5340332212dcc09b38881cc93
https://pure.amc.nl/en/publications/gap-junctions-in-human-umbilical-cord-endothelial-cells-contain-multiple-connexins(83a44e28-f4f0-4802-99b9-d148e3d17977).html

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