Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jongkyu Choi"'
Publikováno v:
Heliyon, Vol 10, Iss 4, Pp e26518- (2024)
Wearable robots are increasingly being deployed for use in industrial fields. However, only a few studies have focused on the usability of wearable robots. The present study evaluated the factors affecting the usability of a harness in securing a wea
Externí odkaz:
https://doaj.org/article/44f86eae7a434ff5ad43c92c24d0c6e3
Autor:
Abinash Khandelwal, Jesse Cushman, Jongkyu Choi, Irina Zhuravka, Abha Rajbhandari, Parvin Valiulahi, Xiandu Li, Chenyu Zhou, Lucio Comai, Sita Reddy
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106732- (2023)
Summary: Patients with myotonic dystrophy type I (DM1) demonstrate visuospatial dysfunction and impaired performance in tasks requiring recognition or memory of figures and objects. In DM1, CUG expansion RNAs inactivate the muscleblind-like (MBNL) pr
Externí odkaz:
https://doaj.org/article/c6355d55e07441898bbdec70af39b1eb
Autor:
Naomi S. Sta Maria, Chenyu Zhou, Se Jung Lee, Parvin Valiulahi, Xiandu Li, Jongkyu Choi, Xiaodan Liu, Russell Jacobs, Lucio Comai, Sita Reddy
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Sta Maria et al. use 2D MRI to study brains from mice deficient in Mbnl1 and/or Mbnl2 as these Muscleblind-like proteins are thought to play a role in Myotonic Dystrophy Type I (DM1). They show brain region-specific reductions in white and gray matte
Externí odkaz:
https://doaj.org/article/7c59e0e8b3664c738c7862241cad5694
Autor:
Jongkyu Choi, Kirkwood E. Personius, Marino DiFranco, Warunee Dansithong, Carl Yu, Saumya Srivastava, Donald M. Dixon, Darshan B. Bhatt, Lucio Comai, Julio L. Vergara, Sita Reddy
Publikováno v:
EBioMedicine, Vol 2, Iss 9, Pp 1034-1047 (2015)
Loss of Muscleblind-like 1 (Mbnl1) is known to alter Clc-1 splicing to result in myotonia. Mbnl1ΔE3/ΔE3/Mbnl3ΔE2 mice, depleted of Mbnl1 and Mbnl3, demonstrate a profound enhancement of myotonia and an increase in the number of muscle fibers with
Externí odkaz:
https://doaj.org/article/75518b18e54c49019f1c7a530c742778
Autor:
Kyunghwan Kim, Bomi Lee, Jaehoon Kim, Jongkyu Choi, Jin-Man Kim, Yue Xiong, Robert G. Roeder, Woojin An
Publikováno v:
Cell Reports, Vol 5, Iss 6, Pp 1690-1703 (2013)
Increasing evidence suggests that linker histone H1 can influence distinct cellular processes by acting as a gene-specific regulator. However, the mechanistic basis underlying such H1 specificity and whether H1 acts in concert with other chromatin-al
Externí odkaz:
https://doaj.org/article/0f8dfcf3ab4c4caebc4e28312edf3252
Autor:
Leonardo C. Clavijo, Jorge Caro, Jongkyu Choi, Jorge A. Caro, Han Tun, Vincent Rowe, S. Ram Kumar, David M. Shavelle, Ray V. Matthews
Publikováno v:
Cardiovascular Revascularization Medicine.
Publikováno v:
J Vis Exp
Noncanonical Wnt signaling regulates intracellular actin filament organization and polarized migration of progenitor cells during embryogenesis. This process requires complex and coordinated paracrine interactions between signal-sending and signal-re
Publikováno v:
Journal of Visualized Experiments.
Autor:
Lucio Comai, Se Jung Lee, Parvin Valiulahi, Sita Reddy, Xiandu Li, Russell E. Jacobs, Xiaodan Liu, Jongkyu Choi, Chenyu Zhou, Naomi S Sta Maria
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Communications Biology
Communications Biology
Myotonic Dystrophy Type I (DM1) patients demonstrate widespread and variable brain structural alterations whose etiology is unclear. We demonstrate that inactivation of the Muscleblind-like proteins, Mbnl1 and Mbnl2, initiates brain structural defect
Autor:
Omar Toubat, Drayton C Harvey, S. Ram Kumar, Hidekazu Tsukamoto, Jahnavi Kishore, Jongkyu Choi, Prashan De Zoysa
Publikováno v:
Birth Defects Res
BACKGROUND: Prenatal alcohol exposure (PAE) is associated with an increased incidence of congenital heart defects (CHD), in particular outflow tract (OFT) defects. However, the variability in the incidence of CHD following PAE has not been fully expl