Zobrazeno 1 - 10
of 403
pro vyhledávání: '"Jong-wook Park"'
Autor:
Seon Min Woo, Seok Kim, Seung Un Seo, Shin Kim, Jong-Wook Park, Gyeonghwa Kim, Yu-Ra Choi, Keun Hur, Taeg Kyu Kwon
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-11 (2022)
Abstract Ubiquitin-specific protease 1 (USP1) is a deubiquitinase involved in DNA damage repair by modulating the ubiquitination of major regulators, such as PCNA and FANCD2. Because USP1 is highly expressed in many cancers, dysregulation of USP1 con
Externí odkaz:
https://doaj.org/article/f6a501b0d6e04abe97dff489f5f643a1
Autor:
Seungyeop Baek, Gun Yung Go, Jong-Wook Park, Jongho Song, Hyun-chul Lee, Seung-Joon Lee, Sangmin Lee, Chuantong Chen, Min-Su Kim, Dongjin Kim
Publikováno v:
Journal of Materials Research and Technology, Vol 17, Iss , Pp 658-678 (2022)
The present study investigates a fatigue property and its microstructural and interface geometrical effect on the resistance element welded (REWed) aluminum (Al)/high-strength steel (Fe) lap joint. The assembled Al/Fe joints were subjected under the
Externí odkaz:
https://doaj.org/article/01f0afd57b9b4e8b9805de21f01e20d2
Autor:
Tak Gyeom Lee, Seon Min Woo, Seung Un Seo, Shin Kim, Jong-Wook Park, Young-Chae Chang, Taeg Kyu Kwon
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12816 (2023)
Ubiquitin-specific protease 2 (USP2) is a deubiquitinase belonging to the USPs subfamily. USP2 has been known to display various biological effects including tumorigenesis and inflammation. Therefore, we aimed to examine the sensitization effect of U
Externí odkaz:
https://doaj.org/article/389877ecce5c4414a035c988ebc02f06
Autor:
Mi-Yeon Jeon, Seon Min Woo, Seung Un Seo, Sang Hyun Kim, Ju-Ock Nam, Shin Kim, Jong-Wook Park, Peter Kubatka, Kyoung-jin Min, Taeg Kyu Kwon
Publikováno v:
Cancers, Vol 12, Iss 10, p 2901 (2020)
Dexamethasone (DEX), a synthetic glucocorticoid, is commonly used as immunosuppressive and chemotherapeutic agent. This study was undertaken to investigate the effects of DEX on the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-indu
Externí odkaz:
https://doaj.org/article/f0db4a1122cb45768312bb04506eeb82
Autor:
Jaegil Kim, Woo-Jae Park, Kwang-Joon Jeong, Sun Hee Kang, Sun Young Kwon, Shin Kim, Jong-Wook Park
Publikováno v:
International Journal of Genomics, Vol 2017 (2017)
Aberrant regulation of microRNA (miRNA) machinery components is associated with various human cancers, including papillary thyroid carcinoma (PTC), which is the most common type of thyroid cancer, and a higher prevalent female malignancy. The purpose
Externí odkaz:
https://doaj.org/article/30c067b6559f4a3b96012f4dc3a34fdf
Autor:
Seon Min Woo, Kyoung-jin Min, Seung Un Seo, Shin Kim, Peter Kubatka, Jong-Wook Park, Taeg Kyu Kwon
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 13, p 3253 (2019)
R428, a selective small molecule Axl inhibitor, is known to have anti-cancer effects, such as inhibition of invasion and proliferation and induction of cell death in cancer cells. The Axl receptor tyrosine kinase is highly expressed in cancer cells a
Externí odkaz:
https://doaj.org/article/63b3925a96f14af2b0421e38de50a989
Autor:
Mi-Yeon Jeon, Kyoung-jin Min, Seon Min Woo, Seung Un Seo, Yung Hyun Choi, Sang Hyun Kim, Dong Eun Kim, Tae-Jin Lee, Shin Kim, Jong-Wook Park, Taeg Kyu Kwon
Publikováno v:
Molecules, Vol 23, Iss 11, p 3030 (2018)
Maritoclax, an active constituent isolated from marine bacteria, has been known to induce Mcl-1 downregulation through proteasomal degradation. In this study, we investigated the sensitizing effect of maritoclax on tumor necrosis factor-related apopt
Externí odkaz:
https://doaj.org/article/c317d10e86ff4425bfae6af9574d0839
Autor:
Seok Kim, Seung Un Seo, Kyoung-Jin Min, Seon Min Woo, Ju-Ock Nam, Peter Kubatka, Shin Kim, Jong-Wook Park, Taeg Kyu Kwon
Publikováno v:
Molecules, Vol 23, Iss 7, p 1614 (2018)
Garcinol is a polyisoprenylated benzophenone derived from the Garcinia indica fruit that possess potential therapeutic effects such as inhibition of inflammation and tumor expansion. Here, we investigated whether garcinol induces TRAIL sensitization
Externí odkaz:
https://doaj.org/article/25bd95f59c494e1482152aeeb6ed7ab7
Autor:
Seon Min Woo, Seung Un Seo, Kyoung-jin Min, Seung-Soon Im, Ju-Ock Nam, Jong-Soo Chang, Shin Kim, Jong-Wook Park, Taeg Kyu Kwon
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 5, p 1309 (2018)
Corosolic acid is one of the pentacyclic triterpenoids isolated from Lagerstroemia speciose and has been reported to exhibit anti-cancer and anti-proliferative activities in various cancer cells. In the present study, we investigated the molecular me
Externí odkaz:
https://doaj.org/article/1f6bd74e2e684cf0852ec5165c22aa98
Autor:
Mi-Yeon Jeon, Kyoung-jin Min, Seon Min Woo, Seung Un Seo, Shin Kim, Jong-Wook Park, Taeg Kyu Kwon
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 12, p 2568 (2017)
Polo-like kinase 1 (PLK1) plays major roles in cell cycle control and DNA damage response. Therefore, PLK1 has been investigated as a target for cancer therapy. Volasertib is the second-in class dihydropteridinone derivate that is a specific PLK1 inh
Externí odkaz:
https://doaj.org/article/e904904ce23345dda4864d4e8a92363f