Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Jong-Lyul Park"'
Autor:
Soobok Joe, Jong-Lyul Park, Jun Kim, Sangok Kim, Ji-Hwan Park, Min-Kyung Yeo, Dongyoon Lee, Jin Ok Yang, Seon-Young Kim
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Detecting structural variations (SVs) at the population level using next-generation sequencing (NGS) requires substantial computational resources and processing time. Here, we compared the performances of 11 SV callers: Delly, Man
Externí odkaz:
https://doaj.org/article/15e2918bbaff46fd87acfd97f221b2e1
Autor:
Seong Eun Lee, Seongyeol Park, Shinae Yi, Na Rae Choi, Mi Ae Lim, Jae Won Chang, Ho-Ryun Won, Je Ryong Kim, Hye Mi Ko, Eun-Jae Chung, Young Joo Park, Sun Wook Cho, Hyeong Won Yu, June Young Choi, Min-Kyung Yeo, Boram Yi, Kijong Yi, Joonoh Lim, Jun-Young Koh, Min Jeong Lee, Jun Young Heo, Sang Jun Yoon, Sung Won Kwon, Jong-Lyul Park, In Sun Chu, Jin Man Kim, Seon-Young Kim, Yujuan Shan, Lihua Liu, Sung-A Hong, Dong Wook Choi, Junyoung O. Park, Young Seok Ju, Minho Shong, Seon-Kyu Kim, Bon Seok Koo, Yea Eun Kang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The role of the serine/glycine metabolic pathway (SGP) has recently been demonstrated in tumors; however, the pathological relevance of the SGP in thyroid cancer remains unexplored. Here, we perform metabolomic profiling of 17 tumor-normal p
Externí odkaz:
https://doaj.org/article/2830ae43ce6c45ee8260e427839f454f
Autor:
Joo-Young Im, Soo Jin Kim, Jong-Lyul Park, Tae-Hee Han, Woo-il Kim, Inhyub Kim, Bomin Ko, So-Young Chun, Mi-Jung Kang, Bo-Kyung Kim, Sol A. Jeon, Seon-Kyu Kim, Incheol Ryu, Seon-Young Kim, Ki-Hoan Nam, Inah Hwang, Hyun Seung Ban, Misun Won
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 1, Pp 235-249 (2024)
Abstract Cytochrome b5 reductase 3 (CYB5R3) is involved in various cellular metabolic processes, including fatty acid synthesis and drug metabolism. However, the role of CYB5R3 in cancer development remains poorly understood. Here, we show that CYB5R
Externí odkaz:
https://doaj.org/article/0b08a891f6e7484ead7d40b35e5ac83c
Autor:
Da-Yeon Kang, Jong-Lyul Park, Min-Kyung Yeo, Sang-Bum Kang, Jin-Man Kim, Ju Seok Kim, Seon-Young Kim
Publikováno v:
BMC Microbiology, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background Inflammatory bowel disease (IBD) is a multifactorial chronic inflammatory disease resulting from dysregulation of the mucosal immune response and gut microbiota. Crohn's disease (CD) and ulcerative colitis (UC) are difficult to di
Externí odkaz:
https://doaj.org/article/4378f6b7468f4b77aa7d16f8a222de66
Autor:
Seung-Jin Park, Yea Eun Kang, Jeong-Hwan Kim, Jong-Lyul Park, Seon-Kyu Kim, Seung-Woo Baek, In Sun Chu, Shinae Yi, Seong Eun Lee, Young Joo Park, Eun-Jae Chung, Jin Man Kim, Hye Mi Ko, Je-Ryong Kim, Seung-Nam Jung, Ho-Ryun Won, Jae Won Chang, Bon Seok Koo, Seon-Young Kim
Publikováno v:
Clinical and Experimental Otorhinolaryngology, Vol 15, Iss 2, Pp 183-193 (2022)
Objectives Thyroid cancer is the most common endocrine tumor, with rapidly increasing incidence worldwide. However, its transcriptomic characteristics associated with immunological signatures, driver fusions, and recurrence markers remain unclear. We
Externí odkaz:
https://doaj.org/article/815ee4677f0e4dbbb87fd57a34c7e6b0
Autor:
Enkhjin Saruuldalai, Jiyoung Park, Dongmin Kang, Seung-Phil Shin, Wonkyun Ronny Im, Hwi-Ho Lee, Jiyoung Joan Jang, Jong-Lyul Park, Seon-Young Kim, Jung-Ah Hwang, Young-Dong Kim, Jung-Hoon Lee, Eun Jung Park, Yeon-Su Lee, In-Hoo Kim, Sang-Jin Lee, Yong Sun Lee
Publikováno v:
Molecular Therapy: Oncolytics, Vol 24, Iss , Pp 683-694 (2022)
Elucidation of the interplay between viruses and host cells is crucial for taming viruses to benefit human health. Cancer therapy using adenovirus, called oncolytic virotherapy, is a promising treatment option but is not robust in all patients. In ad
Externí odkaz:
https://doaj.org/article/b9e36ce9c81d48a3be88aca4495ce821
Autor:
Jong-Lyul Park, Seon-Kyu Kim, Jeong-Hwan Kim, Seok Joong Yun, Wun-Jae Kim, Won Tae Kim, Pildu Jeong, Ho Won Kang, Seon-Young Kim
Publikováno v:
Genomics & Informatics, Vol 16, Iss 3, Pp 71-74 (2018)
Because castration-resistant prostate cancer (CRPC) does not respond to androgen deprivation therapy and has a very poor prognosis, it is critical to identify a prognostic indicator for predicting high-risk patients who will develop CRPC. Here, we re
Externí odkaz:
https://doaj.org/article/77aa0f071ab54bf380310dec61268e6e
Autor:
Sang Cheul Oh, Bo Hwa Sohn, Jae-Ho Cheong, Sang-Bae Kim, Jae Eun Lee, Ki Cheong Park, Sang Ho Lee, Jong-Lyul Park, Yun-Yong Park, Hyun-Sung Lee, Hee-Jin Jang, Eun Sung Park, Sang-Cheol Kim, Jeonghoon Heo, In-Sun Chu, You-Jin Jang, Young-Jae Mok, WonKyung Jung, Baek-Hui Kim, Aeree Kim, Jae Yong Cho, Jae Yun Lim, Yuki Hayashi, Shumei Song, Elena Elimova, Jeannelyn S. Estralla, Jeffrey H. Lee, Manoop S. Bhutani, Yiling Lu, Wenbin Liu, Jeeyun Lee, Won Ki Kang, Sung Kim, Sung Hoon Noh, Gordon B. Mills, Seon-Young Kim, Jaffer A. Ajani, Ju-Seog Lee
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
The prognosis and treatment of gastric cancer is complicated by heterogeneity. Here, the authors reveal two molecular subtypes, the mesenchymal subtype associated with poor survival and chemoresistance, and the epithelial phenotype associated with be
Externí odkaz:
https://doaj.org/article/cb4f389472124edeb3126b20dcd9ed15
Autor:
Ji-Hye Ahn, Hyun-Sung Lee, Ju-Seog Lee, Yeon-Su Lee, Jong-Lyul Park, Seon-Young Kim, Jung-Ah Hwang, Nawapol Kunkeaw, Sung Yun Jung, Tae Jin Kim, Kwang-Soo Lee, Sung Ho Jeon, Inhan Lee, Betty H. Johnson, Jung-Hye Choi, Yong Sun Lee
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Ovarian cancers often display elevated TGF-β signaling but repressed miRNA expression. Here the authors identify that non-coding RNA nc886 expression is induced by TGF-β, which then binds to DICER and impairs miRNA maturation.
Externí odkaz:
https://doaj.org/article/1fef08d16d4f4920ab3eed8776cd77e0
Autor:
Soo-Kyung Park, Sangsoo Kim, Gi-Young Lee, Sung-Yoon Kim, Wan Kim, Chil-Woo Lee, Jong-Lyul Park, Chang-Hwan Choi, Sang-Bum Kang, Tae-Oh Kim, Ki-Bae Bang, Jaeyoung Chun, Jae-Myung Cha, Jong-Pil Im, Kwang-Sung Ahn, Seon-Young Kim, Dong-Il Park
Publikováno v:
Diagnostics, Vol 11, Iss 12, p 2365 (2021)
Crohn’s disease (CD) and ulcerative colitis (UC) can be difficult to differentiate. As differential diagnosis is important in establishing a long-term treatment plan for patients, we aimed to develop a machine learning model for the differential di
Externí odkaz:
https://doaj.org/article/1d5aafe1393a4ee48304dcb5616eb1b1