Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Jong-Bok Seo"'
Autor:
Abu Jubayer Hossain, Rokibul Islam, Jong-Bok Seo, Hwee-Seon Park, Jong-Il Kim, Vikas Kumar, Keun Woo Lee, Jae-Bong Park
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 13697 (2023)
Insulin is a crucial signalling molecule that primarily functions to reduce blood glucose levels through cellular uptake of glucose. In addition to its role in glucose homeostasis, insulin has been shown to regulate cell proliferation. Specifically,
Externí odkaz:
https://doaj.org/article/681bb96ec5154b2e8415242eba897c09
Autor:
Kwadwo Ofori, Anurupa Ghosh, Dinesh Kumar Verma, Darice Wheeler, Gabriela Cabrera, Jong-Bok Seo, Yong-Hwan Kim
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14278 (2023)
Oxidative stress-mediated damage is often a downstream result of Parkinson’s disease (PD), which is marked by sharp decline in dopaminergic neurons within the nigrostriatal regions of the brain, accounting for the symptomatic motor deficits in pati
Externí odkaz:
https://doaj.org/article/3663be3a06e243d98e139bb4c60c5e59
Autor:
Seong-Seop Kim, Yeonju Bae, Osung Kwon, Seung-Hae Kwon, Jong Bok Seo, Eun Mi Hwang, Jae-Yong Park
Publikováno v:
Cells, Vol 11, Iss 20, p 3322 (2022)
Mature astrocytes are characterized by a K+ conductance (passive conductance) that changes with a constant slope with voltage, which is involved in K+ homeostasis in the brain. Recently, we reported that the tandem of pore domains in a weak inward re
Externí odkaz:
https://doaj.org/article/e393b3bc26374256b454e0b1a5d3ab42
Autor:
Sung-Hwa Sohn, Bohyun Kim, Hee Jung Sul, Yoo Jin Kim, Hyeong Su Kim, Hongtae Kim, Jong Bok Seo, Youngho Koh, Dae Young Zang
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-7 (2019)
Abstract Objective Gastric cancer is more open related to genetic predisposition. In our RNA sequencing study on gastric cancer patients, Runt-related transcription factor-3 (RUNX3) expression was significantly down-regulated in gastric cancer. We sh
Externí odkaz:
https://doaj.org/article/8e112e68e01b47d1ab26de1bd076fe54
Publikováno v:
PLoS Pathogens, Vol 17, Iss 1, p e1009261 (2021)
Kaposi's sarcoma-associated herpesvirus (KSHV), which belongs to the gammaherpesvirus subfamily, is associated with the pathogenesis of various tumors. Nuclear enzyme poly(ADP-ribose) polymerase 1 (PARP1) catalyzes the polymerization of ADP-ribose un
Externí odkaz:
https://doaj.org/article/af2c347ea0524a92965b38794dd571fa
Autor:
Anurupa A. Ghosh, Dinesh Kumar Verma, Gabriela Cabrera, Kwadwo Ofori, Karina Hernandez-Quijada, Jae-Kwan Kim, Joo Hee Chung, Michael Moore, Sung Hwan Moon, Jong Bok Seo, Yong-Hwan Kim
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 8, p 4262 (2022)
Parkinson’s disease (PD) is a progressive neurodegenerative motor disorder without an available therapeutic to halt the formation of Lewy bodies for preventing dopaminergic neuronal loss in the nigrostriatal pathway. Since oxidative-stress-mediated
Externí odkaz:
https://doaj.org/article/2126be5426fa43f980b1a6365f5a7771
Autor:
Yoo Jin Kim, A-Ri Cho, Hee Jung Sul, Bohyun Kim, A-Young Kim, Hyeong Su Kim, Jong Bok Seo, Youngho Koh, Dae Young Zang
Publikováno v:
Biology Open, Vol 8, Iss 7 (2019)
Anaplastic lymphoma kinase (ALK) fusion events lead to constitutive activation of the ALK kinase domain, thereby functioning as oncogenic drivers. These fusion proteins have been identified in numerous cancers. Crizotinib, a small molecule inhibitor
Externí odkaz:
https://doaj.org/article/adb785bfa6314bf09a549bf65c30579d
Autor:
Hoibin Jeong, SeonJu Park, Seo-Young Kim, Su-Hyeon Cho, Myeong Seon Jeong, Song-Rae Kim, Jong Bok Seo, Seung Hyun Kim, Kil-Nam Kim
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 20, p 7506 (2020)
Acute myeloid leukemia (AML) is an aggressive type of human leukemia with a low survival rate, and its complete remission remains challenging. Although chemotherapy is the first-line treatment of AML, it exerts toxicity in noncancerous cells when use
Externí odkaz:
https://doaj.org/article/3652bc64b85c4d04a77eac6139cd761e
Publikováno v:
Neural Plasticity, Vol 2016 (2016)
We investigated unknown in vivo functions of Torsin by using Drosophila as a model. Downregulation of Drosophila Torsin (DTor) by DTor-specific inhibitory double-stranded RNA (RNAi) induced abnormal locomotor behavior and increased susceptibility to
Externí odkaz:
https://doaj.org/article/414055f40cb54aa488406d623b9490e1
Autor:
Myung Hee Nam, Eunjung Bang, Jong Bok Seo, Joo Hee Chung, Sung Gil Chi, Yong-Hwan Kim, Seungmin Choi, Kwan Soo Hong
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 98:373-382
Acute myocarditis is an unpredictable heart disease that is caused by inflammation-associated cell death. Although viral infection and drug exposure are known to induce acute myocarditis, the molecular basis for its development remains undefined. Usi