Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jong Yoon Han"'
Publikováno v:
Mass Spectrometry Reviews. 38:483-500
Flexible structures of intrinsically disordered proteins (IDPs) are crucial for versatile functions in living organisms, which involve interaction with diverse partners. Electrospray ionization ion mobility mass spectrometry (ESI-IM-MS) has been wide
Autor:
Yun Kyung Kim, Dongjoon Im, Hugh I. Kim, Sungsu Lim, Jong Yoon Han, Chae Eun Heo, Jee Young Lee, Min Jae Lee
Publikováno v:
ACS chemical neuroscience. 11(19)
Advanced understanding of Alzheimer's disease (AD) and several tauopathies over the past decades indicates the pathological importance of tau aggregation in these diseases. Herein, we demonstrated that adenosine triphosphate (ATP), a highly charged a
Autor:
Jong Yoon Han, Chae Eun Heo, Sungsu Lim, Jeeyoung Lee, Iryna Martsishevska, Dongjoon Im, Min Jae Lee, Yun Kyung Kim, Hugh I. Kim
Advanced understanding of Alzheimer’s disease (AD) and several tauopathies over the past decades indicates the pathological importance of tau aggregation in these diseases. Herein, we demonstrated that adenosine triphosphate (ATP), a highly charged
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ca739f1771f7f689a97fe44714fed5b
https://doi.org/10.26434/chemrxiv.11985357.v1
https://doi.org/10.26434/chemrxiv.11985357.v1
Publikováno v:
Journal of the American Society for Mass Spectrometry. 29:1870-1880
Structural characterization of intrinsically disordered proteins (IDPs) has been a major challenge in the field of protein science due to limited capabilities to obtain full-length high-resolution structures. Native ESI-MS with top-down MS was utiliz
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
α-Synuclein (αSyn) is an intrinsically disordered protein, the aggregation of which is highly related to the pathology of diverse α-synucleinopathies. Various hard divalent metal cations have been shown to affect αSyn aggregation. Especially, Ca2
Publikováno v:
Journal of the American Chemical Society. 139:15437-15445
Regulation of amyloid-β (Aβ) aggregation by metal ions and proteins is essential for understanding the pathology of Alzheimer's disease (AD). Human serum albumin (HSA), a regulator of metal and protein transportation, can modulate metal-Aβ interac
Publikováno v:
Biochimica et biophysica acta. Biomembranes. 1860(9)
Human α‑synuclein (αSyn) is an intrinsically disordered protein (IDP) whose biological and pathological functions in brain neuronal cells have not yet been fully elucidated. αSyn intrinsically participates in aiding neurotransmitter trafficking
Autor:
Hugh I. Kim, Jong Yoon Han, Byung Chul Jung, Joseph A. Loo, Piriya Wongkongkathep, Min Jae Lee, Tae Su Choi, Jee Young Lee
Publikováno v:
Angewandte Chemie (International ed. in English). 57(12)
Structural variation of α-synuclein (αSyn) fibrils has been linked to the diverse etiologies of synucleinopathies. However, little is known about what specific mechanism provides αSyn fibrils with pathologic features. Herein, we demonstrate Cu(II)
Publikováno v:
Scientific Reports
α-Synuclein (αSyn) is an intrinsically disordered protein, the aggregation of which is highly related to the pathology of diverse α-synucleinopathies. Various hard divalent metal cations have been shown to affect αSyn aggregation. Especially, Ca2
Autor:
Hee Cheul Choi, Hugh I. Kim, Jong Yoon Han, Hyungjun Kim, Tae Su Choi, Soyoung Kim, Kwang Seob Jeong, Yoonhoo Ha, Jong-Wha Lee
Publikováno v:
Analytical chemistry. 88(16)
Fullerenes, cage-structured carbon allotropes, have been the subject of extensive research as new materials for diverse purposes. Yet, their formation process is still not clearly understood at the molecular level. In this study, we performed laser d