Zobrazeno 1 - 10
of 252
pro vyhledávání: '"Jong Shin Yoo"'
Autor:
Mijung Oh, Dae-In Ha, Chaeyeon Son, Jeong Gu Kang, Heeyoun Hwang, Su Bin Moon, Minjeong Kim, Jihae Nam, Jung Soo Kim, Sang Yong Song, Yong-Sam Kim, Sangwoo Park, Jong Shin Yoo, Jeong-Heon Ko, Kyoungsook Park
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Sialic acid (SA) is present in glycoconjugates and important in cell–cell recognition, cell adhesion, and cell growth and as a receptor. Among the four mammalian sialidases, cytosolic NEU2 has a pivotal role in muscle and neuronal differen
Externí odkaz:
https://doaj.org/article/ee0763f33c3f4f4d8c30baba1ff0c972
Autor:
Hyejin Kim, Geul Bang, Ye Eun Park, Moonhee Park, Jung Hoon Choi, Myung Jin Oh, Hyun Joo An, Jong Shin Yoo, Youngja Hwang Park, Jin Young Kim, Heeyoun Hwang
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Characterization of therapeutic monoclonal antibodies (mAbs) represents a major challenge for analytical sciences due to their heterogeneity associated with post-translational modifications (PTMs). The protein glycosylation requires comprehensive ide
Externí odkaz:
https://doaj.org/article/aa10f61bca0141b5a9c569df7e326615
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
Kim, Hwang et al. use in vitro and in vivo models of autophagy disorder/metabolic dysfunction to show that in this context, the natural compound kaempferide is an autophagy enhancer and reveal that one of the underlying mechanisms governing this is m
Externí odkaz:
https://doaj.org/article/ca2eeb930c9945b6b07d31949a91e055
Autor:
Soo Youn Lee, Min-Young Song, Dain Kim, Chaewon Park, Da Kyeong Park, Dong Geun Kim, Jong Shin Yoo, Young Hye Kim
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2020)
Numerous clinical trials of drug candidates for Alzheimer’s disease (AD) have failed, and computational drug repositioning approaches using omics data have been proposed as effective alternative approaches to the discovery of drug candidates. Howev
Externí odkaz:
https://doaj.org/article/9f0a066da4204f3cb80ec9e1e49f1ed3
Autor:
Yonghyo Kim, Yutaka Sugihara, Tae Young Kim, Sung Min Cho, Jin Young Kim, Ju Yeon Lee, Jong Shin Yoo, Doona Song, Gyoonhee Han, Melinda Rezeli, Charlotte Welinder, Roger Appelqvist, György Marko-Varga, Ho Jeong Kwon
Publikováno v:
Biomolecules, Vol 10, Iss 4, p 508 (2020)
Although natural products are an important source of drugs and drug leads, identification and validation of their target proteins have proven difficult. Here, we report the development of a systematic strategy for target identification and validation
Externí odkaz:
https://doaj.org/article/c0c1eaf16c404d448dab81d12e8deefa
Autor:
Andrew J. Percy, Jessica Tamura-Wells, Juan Pablo Albar, Kerman Aloria, Ardeshir Amirkhani, Gabriel D.T. Araujo, Jesus M. Arizmendi, Francisco J. Blanco, Francesc Canals, Jin-Young Cho, Núria Colomé-Calls, Fernando J. Corrales, Gilberto Domont, Guadalupe Espadas, Patricia Fernandez-Puente, Concha Gil, Paul A. Haynes, Maria Luisa Hernáez, Jin Young Kim, Arthur Kopylov, Miguel Marcilla, Mathew J. McKay, Mehdi Mirzaei, Mark P. Molloy, Leanne B. Ohlund, Young-Ki Paik, Alberto Paradela, Mark Raftery, Eduard Sabidó, Lekha Sleno, Daniel Wilffert, Justina C. Wolters, Jong Shin Yoo, Victor Zgoda, Carol E. Parker, Christoph H. Borchers
Publikováno v:
EuPA Open Proteomics, Vol 8, Iss C, Pp 6-15 (2015)
The reproducibility of plasma protein quantitation between laboratories and between instrument types was examined in a large-scale international study involving 16 laboratories and 19 LC–MS/MS platforms, using two kits designed to evaluate instrume
Externí odkaz:
https://doaj.org/article/3a68a7c1edbe473fa3c4d7fa483f95d3
Publikováno v:
Journal of Analytical Science and Technology, Vol 1, Iss 1, Pp 1-14 (2010)
For proteome analysis, various experimental protocols using mass spectrometry have been developed over thelast decade. The different protocols have differing performances and degrees of accuracy. Furthermore, the “best”protocol for a proteomic an
Externí odkaz:
https://doaj.org/article/f9005bce9b21498f921b4f6b28f5a9c8
Autor:
Hanna Lee, Meiying Song, Nara Shin, Chang Hoon Shin, Byung Soh Min, Hyon-Suk Kim, Jong Shin Yoo, Hoguen Kim
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34318 (2012)
High mobility group box 1 protein (HMGB1), a nuclear protein, can be translocated to the cytoplasm and secreted in colon cancer cells. However, the diagnostic significance of HMGB1 has not been evaluated in colorectal carcinomas. For this purpose, we
Externí odkaz:
https://doaj.org/article/3a6be9cf1c604a278055fe0701aa5f69
Publikováno v:
Journal of Analytical Science and Technology, Vol 2, Iss Supplement A, Pp A135-A139 (2011)
Mass spectrometry (MS) can identify new proteins and assay the amount of the biomarker proteins that need to be validated as a viable cancer candidate. Low abundant peptides from plasma glycoprotein were identified by ultra high resolution 15T MALDI-
Externí odkaz:
https://doaj.org/article/a0e9160c5a8744ba9cbcef72e9e0ffed
Autor:
Sung-Min Ahn, Kyunghee Byun, Kun Cho, Jin Young Kim, Jong Shin Yoo, Deokhoon Kim, Sun Ha Paek, Seung U Kim, Richard J Simpson, Bonghee Lee
Publikováno v:
PLoS ONE, Vol 3, Iss 7, p e2829 (2008)
Albumin, an abundant plasma protein with multifunctional properties, is mainly synthesized in the liver. Albumin has been implicated in Alzheimer's disease (AD) since it can bind to and transport amyloid beta (Abeta), the causative agent of AD; album
Externí odkaz:
https://doaj.org/article/1d4c66e47895490ba753036edddbe629