Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jong Ryul Ha"'
Autor:
Jong Ryul Ha, Jeong Hyun Lee, Jong Ho Jung, Sung Kwon Ko, Seung Woo Shin, Choon-Gon Jang, Yong Kwang Lim, Eun-Joo Shin, Yunsung Nam, Hyoung-Chun Kim, Ji Hoon Jeong, Jong Seok Chae
Publikováno v:
Food and Chemical Toxicology. 65:280-292
Methylphenidate (MP) has become the primary drug of choice for treatment of attention-deficit/hyperactivity disorder (ADHD). However, its psychotropic effects severely hamper long-term clinical use. We evaluated the effects of YY162, which consists o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d8b8aeb9a8860f1c6e07c202bad960b
https://doi.org/10.1016/j.fct.2013.12.046
https://doi.org/10.1016/j.fct.2013.12.046
Autor:
Ho Chul Kang, Min-Duk Seo, Seung-Hyeon Seok, Tai-Geun Jung, Taeheun Oh, Jong-Ryul Ha, Dae-Won Sim, Dongsun Park, Ji-Hun Kim, Hyung-Sik Won, Young Pil Kim, Seonghwan Lee
Publikováno v:
Applied microbiology and biotechnology. 100(24)
Fragment engineering of monoclonal antibodies (mAbs) has emerged as an excellent paradigm to develop highly efficient therapeutic and/or diagnostic agents. Engineered mAb fragments can be economically produced in bacterial systems using recombinant D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c603ccb7e6b535163f83954ecf7fed76
https://pubmed.ncbi.nlm.nih.gov/27470143
https://pubmed.ncbi.nlm.nih.gov/27470143
Autor:
Jung Bok Lee, Bora Kim, Sejin Jeon, Mickie Bhatia, Jong-Ryul Ha, Min-Kyoung Kim, S. B. Oh, Goo Taeg Oh, Ki-Hoan Nam, Dae Yong Kim
Publikováno v:
Archives of Pharmacal Research. 35:1979-1988
Embryonic stem (ES) cells may be used as an alternative source of functionally intact cardiomyocytes for ischemic heart disease. Several natural and synthetic small molecules have been identified as useful tools for controlling and manipulating stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0317d3fd8599fd983aa24f87e722144e
https://doi.org/10.1007/s12272-012-1115-6
https://doi.org/10.1007/s12272-012-1115-6
Autor:
Sun Hee Kim, Jong Ryul Ha, Pann-Ghill Suh, Joo Young Cha, Yun-Hee Kim, Jang Hyun Choi, Seul Ki Lee, Se Woong Oh, Sung Ho Ryu, Yong Ryoul Yang
Publikováno v:
Annals of the New York Academy of Sciences. 1138:393-403
3'-Phosphoinositide-dependent kinase-1 (PDK1) has been identified for its ability to phosphorylate and activate Akt. Accumulated studies have shown that the activation of the PDK1/Akt pathway plays a pivotal role in cell survival, proliferation, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ade182c4414d3f2fb6cebb6cdd19bc
https://doi.org/10.1196/annals.1414.041
https://doi.org/10.1196/annals.1414.041
Publikováno v:
Pharmacology & Toxicology. 89:23-29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f74ae8deb7ce81aa0e6427ccaf20e25
https://doi.org/10.1111/j.1600-0773.2001.890104.x
https://doi.org/10.1111/j.1600-0773.2001.890104.x
Autor:
Jia-Ling Teo, Jong Ryul Ha, Randall T. Moon, Hong Ma, Katayoon H. Emami, Sung Hwan Moon, Hak Yeop Kim, Kwang Won Jeong, Se Woong Oh, Masakatsu Eguchi, Cu Nguyen, Michael G. Kahn, Dae Hoon Kim
Publikováno v:
Proceedings of the National Academy of Sciences. 101:12682-12687
Inherited and somatic mutations in the adenomatous polyposis coli occur in most colon cancers, leading to activation of β-catenin-responsive genes. To identify small molecule antagonists of this pathway, we challenged transformed colorectal cells wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8607e50ab72242bf4b83c4cba136199
https://doi.org/10.1073/pnas.0404875101
https://doi.org/10.1073/pnas.0404875101
Publikováno v:
Chemico-Biological Interactions. 139:61-77
Oltipraz is a cancer chemopreventive agent active against a wide variety of chemical carcinogens. In spite of the intense chemoprevention and toxicology studies on oltipraz, no information is available on its antifibrotic efficacy. In the present stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7d6a8146d5913ea62ac10b9a39fde1c
https://doi.org/10.1016/s0009-2797(01)00286-1
https://doi.org/10.1016/s0009-2797(01)00286-1
Publikováno v:
Archives of Pharmacal Research. 24:323-326
Previous studies have demonstrated that CW252053, a quinazoline antifolate, exhibits potent inhibitory activity against thymidylate synthase (TS) as well as cytotoxic activity against tumor cell lines in vitro. In this study, we evaluated the in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4b27089d60c34d9c61c56282f707f1
https://doi.org/10.1007/bf02975100
https://doi.org/10.1007/bf02975100
Publikováno v:
Biologicalpharmaceutical bulletin. 32(8)
A series of methylenedioxybenzene compounds were synthesized and found to have hepatoprotective effects in chemical-induced hepatotoxicity models. The purpose of the present study was to investigate the anti-fibrotic effects of a synthetic methylened
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43086c1b8b6af4fe232eef3a9491dbb7
https://pubmed.ncbi.nlm.nih.gov/19652375
https://pubmed.ncbi.nlm.nih.gov/19652375
Autor:
Dong Geun Lee, Hong Gi Kim, Jong Myung Kim, Jong Ryul Ha, Jin-Man Lee, Sang-Han Lee, Jong Guk Kim, Byung Oh Kim, Se Woong Oh
Publikováno v:
Journal of microbiology and biotechnology. 18(11)
CW-270031 is a novel synthesized carbapenem antibiotic with a broad antimicrobial activity. Carbapenem antibiotics are well known for their nephrotoxicity. In this study, we evaluated the nephrotoxicity potential of this compound in rabbits, which ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f486c2b9e29985b56045e072514cfd0
https://pubmed.ncbi.nlm.nih.gov/19047819
https://pubmed.ncbi.nlm.nih.gov/19047819