Zobrazeno 1 - 10
of 1 643
pro vyhledávání: '"Jong Hyun KIM"'
Autor:
Jaehyun Hwang, In-Young Jang, Eunseo Bae, Jaeseok Choi, Jeong Hwan Kim, Sang Beum Lee, Jong Hyun Kim, Jae Pil Lee, Ho Young Jang, Hyoung Tae Kim, Jong-Woo Lim, Minjoo Yeom, Eunhee Jang, Seong-Eun Kim, Hyoung Hwa Jeong, Jung Woo Kim, Seung-Yong Seong, Daesub Song, Woonsung Na
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 176, Iss , Pp 116781- (2024)
Influenza A virus causes numerous deaths and infections worldwide annually. Therefore, we have considered nanobodies as a potential treatment for patients with severe cases of influenza. We developed a nanobody that was expected to have protective ef
Externí odkaz:
https://doaj.org/article/0b7cead65216444aa333b2d39ec2986d
Autor:
MinDong Sung, Jong Hyun Kim, Hyun-Seok Min, Sooyoung Jang, JaeSeong Hong, Bo Kyu Choi, JuHye Shin, Kyung Soo Chung, Yu Rang Park
Publikováno v:
Light: Science & Applications, Vol 12, Iss 1, Pp 1-12 (2023)
Abstract Sepsis is a dysregulated immune response to infection that leads to organ dysfunction and is associated with a high incidence and mortality rate. The lack of reliable biomarkers for diagnosing and prognosis of sepsis is a major challenge in
Externí odkaz:
https://doaj.org/article/716d1957044c44d084530426db7d6a56
Autor:
Changhwan Yoon, Jun Lu, Yukyung Jun, Yun-Suhk Suh, Bang-Jin Kim, Jacob E. Till, Jong Hyun Kim, Sara H. Keshavjee, Sandra Ryeom, Sam S. Yoon
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-16 (2023)
Abstract Our previous work showed that KRAS activation in gastric cancer cells leads to activation of an epithelial-to-mesenchymal transition (EMT) program and generation of cancer stem-like cells (CSCs). Here we analyze how this KRAS activation in g
Externí odkaz:
https://doaj.org/article/dc3a8ab1a8144e6a835f77aa4c98698b
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract The efficacy of decompressive craniectomy (DC) for traumatic brain injury (TBI) have been investigated in two recent randomized clinical trials (RCTs) and DC is recommended as an optional treatment for improving overall survival compared to
Externí odkaz:
https://doaj.org/article/7c66f5474c05455c96c5c0ec859126ae
Publikováno v:
Polymer Testing, Vol 130, Iss , Pp 108316- (2024)
Magnetic soft composites have emerged as a promising soft actuator with a high degree of precision in the magnetic field stimuli system. But, their mass manufacturing strategies have yet to be developed, and most studies focus on small-scale near-net
Externí odkaz:
https://doaj.org/article/69b25d558e3e4f73a6fd17ed87c5f52f
Autor:
R. Tyler Mertens, Jong Hyun Kim, Samuel Ofori, Chibuzor Olelewe, Paul J. Kamitsuka, Gunnar F. Kwakye, Samuel G. Awuah
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 170, Iss , Pp 116010- (2024)
Triple-negative breast cancer (TNBC) is associated with metabolic heterogeneity and poor prognosis with limited treatment options. New treatment paradigms for TNBC remains an unmet need. Thus, therapeutics that target metabolism are particularly attr
Externí odkaz:
https://doaj.org/article/7b0052f6d7a84bc88ec1ced1acc9d4e4
Autor:
Mi-Gyeong Gwon, Jaechan Leem, Hyun-Jin An, Hyemin Gu, Seongjae Bae, Jong Hyun Kim, Kwan-Kyu Park
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 34, Iss , Pp 102036- (2023)
Atopic dermatitis (AD) is a common inflammatory skin disease caused by an immune disorder. Mast cells are known to be activated and granulated to maintain an allergic reaction, including rhinitis, asthma, and AD. Although hypoxia-inducible factor-1 a
Externí odkaz:
https://doaj.org/article/8fa66ff47c004a729309793f16b22a9f
Autor:
Changhwan Yoon, Jun Lu, Yukyung Jun, Yun-Suhk Suh, Bang-Jin Kim, Jacob E. Till, Jong Hyun Kim, Sara H. Keshavjee, Sandra Ryeom, Sam S. Yoon
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/8b12d883609b4b59907fa8b514bb6bec
Autor:
Ina Yoon, Sulhee Kim, Minjae Cho, Kyung Ah You, Jonghyeon Son, Caroline Lee, Ji Hun Suh, Da‐Jeong Bae, Jong Min Kim, Sinae Oh, Songhwa Park, Sanga Kim, Seong Hyeok Cho, Seonha Park, Kyuhyeon Bang, Minjeong Seo, Jong Hyun Kim, Bongyong Lee, Joon Seok Park, Kwang Yeon Hwang, Sunghoon Kim
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 7, Pp n/a-n/a (2023)
Abstract Prolyl‐tRNA synthetase 1 (PARS1) has attracted much interest in controlling pathologic accumulation of collagen containing high amounts of proline in fibrotic diseases. However, there are concerns about its catalytic inhibition for potenti
Externí odkaz:
https://doaj.org/article/c423ef5903cf4af4baee1d3b57474eab
Autor:
Kibum Kim, Hee Chan Yoo, Byung Gyu Kim, Sulhee Kim, Yulseung Sung, Ina Yoon, Ya Chun Yu, Seung Joon Park, Jong Hyun Kim, Kyungjae Myung, Kwang Yeon Hwang, Sunghoon Kim, Jung Min Han
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Leucyl-tRNA synthetase 1 (LARS1) is a leucine sensor for mTORC1 signaling and regulates leucine utilization depending on glucose availability. Here, the author show that O-GlcNAcylation of LARS1 is crucial for its ability to regulate mTORC1 activity
Externí odkaz:
https://doaj.org/article/b24a9f59b90d4b6bb4d56ba51f1109ee