Výsledky vyhledávání - "Jong Duk Park"

Akademický článek

Cofactor Selectivity in Methylmalonyl Coenzyme A Mutase, a Model Cobamide-Dependent Enzyme

Autor: Olga M. Sokolovskaya, Kenny C. Mok, Jong Duk Park, Jennifer L. A. Tran, Kathryn A. Quanstrom, Michiko E. Taga

Publikováno v: mBio, Vol 10, Iss 5 (2019)

ABSTRACT Cobamides, a uniquely diverse family of enzyme cofactors related to vitamin B12, are produced exclusively by bacteria and archaea but used in all domains of life. While it is widely accepted that cobamide-dependent organisms require specific

Externí odkaz: https://doaj.org/article/674954d760e44c9289ab047d2dccba1c

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On the Structure of Thailandene A: Synthetic Examination of the Cryptic Natural Product Aided by a Theoretical Approach

Autor: Marius Aursnes, Karoline G. Primdahl, Åsmund Kaupang, Jong-Duk Park, Mohammad R. Seyedsayamdost, Jens M. J. Nolsøe

Publikováno v: Synthesis. 54:1733-1744

Phenotype-guided transposon mutagenesis has emerged as a valuable tool to access cryptic metabolites encoded in bacterial genomes. Recently, the method was demonstrated by inducing silent biosynthetic gene clusters in Burkholderia thailandensis. Amon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::695b4d6915379bca93d2c12f18922c39
https://doi.org/10.1055/s-0041-1737242

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The Small-Molecule Language of Dynamic Microbial Interactions

Autor: Yifan Zhang, Étienne Gallant, Jong-Duk Park, Mohammad R. Seyedsayamdost

Publikováno v: Annu Rev Microbiol

Although microbes are routinely grown in monocultures in the laboratory, they are almost never encountered as single species in the wild. Our ability to detect and identify new microorganisms has advanced significantly in recent years, but our unders

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371ecc1278ca6bf503aa0fc7715c72eb
https://europepmc.org/articles/PMC10171915/

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Structural Elucidation of Cryptic Algaecides in Marine Algal‐Bacterial Symbioses by NMR Spectroscopy and MicroED

Autor: Mohammad R. Seyedsayamdost, Kyuho Moon, Yuchen Li, Jong-Duk Park, Seoung Rak Lee, Esther J. Han

Publikováno v: Angew Chem Int Ed Engl

Microbial secondary metabolite discovery is often conducted in pure monocultures. In a natural setting, however, where metabolites are constantly exchanged, bio-synthetic precursors are likely provided by symbionts or hosts. In the current work, we r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e7d6f43267498d6f1f67014ae6076ae
https://doi.org/10.1002/anie.202114022

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Thailandenes, Cryptic Polyene Natural Products Isolated from Burkholderia thailandensis Using Phenotype-Guided Transposon Mutagenesis

Autor: Cheryl N. Miller, Jong-Duk Park, Jeremy Jacobsen, Kyuho Moon, David DeShazer, Dainan Mao, Fei Xu, Christopher C. Ebmeier, Mohammad R. Seyedsayamdost, Jessica Rose, William M. Old

Publikováno v: ACS Chemical Biology. 15:1195-1203

Burkholderia thailandensis has emerged as a model organism for investigating the production and regulation of diverse secondary metabolites. Most of the biosynthetic gene clusters encoded in B. thailandensis are silent, motivating the development of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0bc2a9764256355de5bc8c1110ca89ae
https://doi.org/10.1021/acschembio.9b00883

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