Zobrazeno 1 - 10
of 215
pro vyhledávání: '"Jong Chan Park"'
Autor:
So‐Yeol Yoo, Yong‐Hyeon Mun, Nae‐Won Kang, Jang Mo Koo, Dong Hwan Lee, Ji Hoon Yoo, Sang Min Lee, Seokjin Koh, Jong Chan Park, Taejung Kim, Eun Kyung Shin, Han Sol Lee, Jaehoon Sim, Keon Wook Kang, Sang Kyum Kim, Cheong‐Weon Cho, Myeong Gyu Kim, Dae‐Duk Kim, Jae‐Young Lee
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 6, Pp n/a-n/a (2023)
Abstract Recent studies on osteosarcoma regimens have mainly focused on modifying the combination of antineoplastic agents rather than enhancing the therapeutic efficacy of each component. Here, an albumin nanocluster (NC)‐assisted methotrexate (MT
Externí odkaz:
https://doaj.org/article/5b0aa7f7b3d848cfb0b4051c1f285248
Publikováno v:
Electronics Letters, Vol 58, Iss 20, Pp 756-758 (2022)
Abstract Stator wedge tightness inspection is one of the most important periodic inspections carried out on required for large‐capacity generators. The traditional wedge tightness inspection method enforces inspectors to enter the narrow and uncomf
Externí odkaz:
https://doaj.org/article/a3e3a93c80e94dde8b8fc735912fdd08
Autor:
Jong‐Chan Park, Natalia Barahona‐Torres, So‐Yeong Jang, Kin Y. Mok, Haeng Jun Kim, Sun‐Ho Han, Kwang‐Hyun Cho, Xiaopu Zhou, Amy K. Y. Fu, Nancy Y. Ip, Jieun Seo, Murim Choi, Hyobin Jeong, Daehee Hwang, Dong Young Lee, Min Soo Byun, Dahyun Yi, Jong Won Han, Inhee Mook‐Jung, John Hardy
Publikováno v:
Advanced Science, Vol 9, Iss 23, Pp n/a-n/a (2022)
Abstract Recent multi‐omics analyses paved the way for a comprehensive understanding of pathological processes. However, only few studies have explored Alzheimer’s disease (AD) despite the possibility of biological subtypes within these patients.
Externí odkaz:
https://doaj.org/article/34ef263cdb004c159da392487b587d25
Autor:
Jong-Chan Park, Keum Sim Jung, Jiyeong Kim, Ji Sung Jang, Sunghoon Kwon, Min Soo Byun, Dahyun Yi, Gihwan Byeon, Gijung Jung, Yu Kyeong Kim, Dong Young Lee, Sun-Ho Han, Inhee Mook-Jung
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-10 (2021)
Abstract Background Alzheimer’s disease (AD) is an irreversible neurodegenerative disease characterized by the hallmark finding of cerebral amyloid deposition. Many researchers have tried to predict the existence of cerebral amyloid deposition by u
Externí odkaz:
https://doaj.org/article/861d8581c821400a9be71d6ffd8879c9
Autor:
Jong-Chan Park, So-Yeong Jang, Dongjoon Lee, Jeongha Lee, Uiryong Kang, Hongjun Chang, Haeng Jun Kim, Sun-Ho Han, Jinsoo Seo, Murim Choi, Dong Young Lee, Min Soo Byun, Dahyun Yi, Kwang-Hyun Cho, Inhee Mook-Jung
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Developing effective drugs for Alzheimer’s disease (AD), the most common cause of dementia, has been difficult because of complicated pathogenesis. Here, the authors report an efficient network-based drug-screening platform developed by integrating
Externí odkaz:
https://doaj.org/article/76e852796f214d3b97b10bab8107b2db
Autor:
Jieun Seo, Min Soo Byun, Dahyun Yi, Jun Ho Lee, So Yeon Jeon, Seong A. Shin, Yu Kyeong Kim, Koung Mi Kang, Chul-Ho Sohn, Gijung Jung, Jong-Chan Park, Sun-Ho Han, Jayoung Byun, Inhee Mook-Jung, Dong Young Lee, Murim Choi, for the KBASE Research Group
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-10 (2020)
Abstract Introduction Although the heritability of sporadic Alzheimer’s disease (AD) is estimated to be 60–80%, addressing the genetic contribution to AD risk still remains elusive. More specifically, it remains unclear whether genetic variants a
Externí odkaz:
https://doaj.org/article/853989c59b37417b818d152f121c50db
Autor:
Yong-Hee Cho, Eun Ji Ro, Jeong-Su Yoon, Tomohiro Mizutani, Dong-Woo Kang, Jong-Chan Park, Tae Il Kim, Hans Clevers, Kang-Yell Choi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The relative enrichment of cancer stem cells after treatment results in tumour recurrence. Here, the authors show a mechanism where p53 induces WNT3, which increases the number of colorectal cancer stem cells following treatment of 5-fluorouracil.
Externí odkaz:
https://doaj.org/article/734b08cd776a44bf9b6930273cd2ce5d
Autor:
Won-Ji Ryu, Jeong Dong Lee, Jong-Chan Park, Pu-Hyeon Cha, Yong-Hee Cho, Jee Ye Kim, Joo Hyuk Sohn, Soonmyung Paik, Kang-Yell Choi
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 5, Pp 832-842 (2020)
Breast cancer: Dual pathway blockade shrinks aggressive tumors The triple-negative breast cancer (TNBC), a highly aggressive form of breast cancer may be susceptible to drug therapy that targets two critical signaling pathways, one that governs cell
Externí odkaz:
https://doaj.org/article/4bb29888b7d9430e820c489b57c846cf
Publikováno v:
Applied Sciences, Vol 12, Iss 21, p 11297 (2022)
In order to reduce the large damage caused by train derailment, protective facilities of various shapes and conditions can be installed on railroad tracks. These protective facilities are referred to as derailment containment provisions (DCPs) and th
Externí odkaz:
https://doaj.org/article/99c32bd734d646398519e5f56ac8dedf
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-13 (2019)
Abstract Background Stabilization of RAS is a key event for the hyper-activation of Wnt/β-catenin signaling and activation of cancer stem cell (CSC) in colorectal cancer (CRC). WD Repeat protein 76 (WDR76) mediates the polyubiquitination-dependent d
Externí odkaz:
https://doaj.org/article/cf8fa63e536f4e02b42e624ea19cad07