Zobrazeno 1 - 10
of 514
pro vyhledávání: '"Jong‐Mu Sun"'
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 3, Pp 1167-1176 (2024)
Abstract Background We aimed to identify the impact of muscle mass on locally advanced oesophageal cancer (LAEC) in elderly patients receiving neoadjuvant chemoradiation therapy (NACRT). Methods We reviewed the medical records of 345 patients diagnos
Externí odkaz:
https://doaj.org/article/af7d1bfea5ee4bdd8e2c18ca3b7d62c4
Autor:
Nayoung Kim, Sehhoon Park, Areum Jo, Hye Hyeon Eum, Hong Kwan Kim, Kyungjong Lee, Jong Ho Cho, Bo Mi Ku, Hyun Ae Jung, Jong-Mu Sun, Se-Hoon Lee, Jin Seok Ahn, Jung-Il Lee, Jung Won Choi, Dasom Jeong, Minsu Na, Huiram Kang, Jeong Yeon Kim, Jung Kyoon Choi, Hae-Ock Lee, Myung-Ju Ahn
Publikováno v:
eLife, Vol 13 (2024)
This study investigates the variability among patients with non-small cell lung cancer (NSCLC) in their responses to immune checkpoint inhibitors (ICIs). Recognizing that patients with advanced-stage NSCLC rarely qualify for surgical interventions, i
Externí odkaz:
https://doaj.org/article/a6cc1516727f4f3688947a807a310c49
Autor:
Young-gon Kim, Boram Lee, Changhee Ha, Cheonghwa Lee, Hyun Ae Jung, Jong-Mu Sun, Se-Hoon Lee, Myung-Ju Ahn, Yoon-La Choi, Sehhoon Park, Jong-Won Kim
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionNumerous studies have suggested high concordance between tissue and circulating tumor DNA (ctDNA) comprehensive genomic profiling (CGP) tests but only few of them focused on fusions. In addition, atypical breakpoints occasionally detected
Externí odkaz:
https://doaj.org/article/dbc81487172d4e9cb14580b7c5c23ec4
Autor:
Dae-Ho Choi, MD, Miso Kim, MD, PhD, Young Saing Kim, MD, PhD, Keon Uk Park, MD, PhD, Jang Ho Cho, MD, PhD, Hongsik Kim, MD, PhD, Ki Hyeong Lee, MD, PhD, Heejoon Ahn, MD, PhD, Il-Hwan Kim, MD, PhD, Kyung-Hee Lee, MD, PhD, Gyeong-Won Lee, MD, PhD, Seong Yoon Yi, MD, PhD, Beung chul Ahn, MD, PhD, Min-Young Lee, MD, PhD, Hyun Ae Jung, MD, PhD, Sehhoon Park, MD, PhD, Jong-Mu Sun, MD, PhD, Jin Seok Ahn, MD, PhD, Se-Hoon Lee, MD, PhD, Myung-Ju Ahn, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 12, Pp 100734- (2024)
Introduction: The role of maintenance durvalumab after definitive concurrent chemoradiotherapy (CCRT) in unresectable locally advanced NSCLC with EGFR mutation or ALK translocation remains unclear. We compared the effectiveness of durvalumab maintena
Externí odkaz:
https://doaj.org/article/5adc6e00d2074509b50a281b9eca7f23
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2185 (2024)
Objectives: The design of cancer clinical trials incorporating biomarkers depends on various factors, including the trial phase, the type of biomarker and whether its role has been validated. This article aims to present a method for designing and an
Externí odkaz:
https://doaj.org/article/ade355a974ff42b389ff61cf2af0ff7d
Autor:
Sehhoon Park, Tae Hee Hong, Soohyun Hwang, Simon Heeke, Carl M. Gay, Jiyeon Kim, Hyun-Ae Jung, Jong-Mu Sun, Jin Seok Ahn, Myung-Ju Ahn, Jong Ho Cho, Yong Soo Choi, Jhingook Kim, Young Mog Shim, Hong Kwan Kim, Lauren Averett Byers, John V. Heymach, Yoon-La Choi, Se-Hoon Lee, Keunchil Park
Publikováno v:
EBioMedicine, Vol 102, Iss , Pp 105062- (2024)
Summary: Background: Recent studies have reported the predictive and prognostic value of novel transcriptional factor-based molecular subtypes in small-cell lung cancer (SCLC). We conducted an in-depth analysis pairing multi-omics data with immunohis
Externí odkaz:
https://doaj.org/article/40a1e82c84034502bbbe4835972d5109
Autor:
Sehhoon Park, Hongui Cha, Hong Sook Kim, Boram Lee, Soyeon Kim, Tae Min Kim, Hyu Ae Jung, Jong‐Mu Sun, Jin Seok Ahn, Myung‐Ju Ahn, Keunchil Park, Woong‐Yang Park, Se‐Hoon Lee
Publikováno v:
Cancer Medicine, Vol 12, Iss 6, Pp 7639-7650 (2023)
Abstract Background The chemokine CXCL13 is known to influence local anti‐tumor immunity by recruiting immune cells and forming tertiary lymphoid structures (TLS). It has been hypothesized that TLS, led by the expression of CXCL13, could be a predi
Externí odkaz:
https://doaj.org/article/95d32146a249483aba3dee9012209aa9
Publikováno v:
Thoracic Cancer, Vol 14, Iss 6, Pp 624-635 (2023)
Abstract Background The role of adjuvant chemotherapy in esophageal squamous cell carcinoma (ESCC) remains controversial. This study aimed to evaluate the impact of adjuvant chemotherapy on survival in patients with positive nodes after surgery for E
Externí odkaz:
https://doaj.org/article/488a782a6fa2447c92270d4fb1f92e05
Autor:
Bo Mi Ku, Sungwon Park, Sehhoon Park, Hyun Ae Jung, Jong-Mu Sun, Se-Hoon Lee, Jin Seok Ahn, Yoon-La Choi, Myung-Ju Ahn
Publikováno v:
Precision and Future Medicine, Vol 6, Iss 4, Pp 233-242 (2022)
Purpose Mesenchymal-epithelial transition tyrosine kinase receptor (MET) amplification is one of the common acquired resistance mechanisms to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). To evaluate the usefulness of scree
Externí odkaz:
https://doaj.org/article/80797f7b73f24d7e8f3b5caf7f97b856
Autor:
Se‐Hoon Lee, Yeongmin Kim, Bu‐Nam Jeon, Gihyeon Kim, Jinyoung Sohn, Youngmin Yoon, Sujeong Kim, Yunjae Kim, Hyemin Kim, Hongui Cha, Na‐Eun Lee, Hyunsuk Yang, Joo‐Yeon Chung, A‐Reum Jeong, Yun Yeon Kim, Sang Gyun Kim, Yeonhee Seo, Sehhoon Park, Hyun Ae Jung, Jong‐Mu Sun, Jin Seok Ahn, Myung‐Ju Ahn, Hansoo Park, Kyoung Wan Yoon
Publikováno v:
Advanced Science, Vol 10, Iss 17, Pp n/a-n/a (2023)
Abstract Immune checkpoint inhibitor (ICI) clinically benefits cancer treatment. However, the ICI responses are only achieved in a subset of patients, and the underlying mechanisms of the limited response remain unclear. 160 patients with non‐small
Externí odkaz:
https://doaj.org/article/4ff970230138448ab38c9661f2b162ca