Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jones T Nauseef"'
Autor:
Yajas Shah, Scott Kulm, Jones T Nauseef, Zhengming Chen, Olivier Elemento, Kevin H Kensler, Ravi N Sharaf
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 4, p e1011990 (2024)
Prostate cancer is a heritable disease with ancestry-biased incidence and mortality. Polygenic risk scores (PRSs) offer promising advancements in predicting disease risk, including prostate cancer. While their accuracy continues to improve, research
Externí odkaz:
https://doaj.org/article/9b1c0fad8d784c70bdca6d450b9673f8
Autor:
Trenton L Place, Jones T Nauseef, Maina K Peterson, Michael D Henry, James J Mezhir, Frederick E Domann
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83021 (2013)
Prolyl-4-hydroxylation by the intracellular prolyl-4-hydroxylase enzymes (PHD1-3) serves as a master regulator of environmental oxygen sensing. The activity of these enzymes is tightly tied to tumorigenesis, as they regulate cell metabolism and angio
Externí odkaz:
https://doaj.org/article/6aa167b777d14e0999afcc5dfdba1678
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50973 (2012)
During metastasis, cancer cells enter the circulation in order to gain access to distant tissues, but how this fluid microenvironment influences cancer cell biology is poorly understood. A longstanding view is that circulating cancer cells derived fr
Externí odkaz:
https://doaj.org/article/7e83707416dd4f94b058d4bd4de694ab
Autor:
Kritika Subramanian, Juana Martinez, Sandra Huicochea Castellanos, Jana Ivanidze, Himanshu Nagar, Sean Nicholson, Trisha Youn, Jones T. Nauseef, Scott Tagawa, Joseph R. Osborne
Prostate cancer (PC) staging with conventional imaging often includes multiparametric magnetic resonance (MR) of the prostate, computed tomography (CT) of the chest, abdomen, and pelvis, and whole-body bone scintigraphy. The recent development of hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2a755c18761a7776c2af2d656d8473a
https://lirias.kuleuven.be/handle/20.500.12942/722215
https://lirias.kuleuven.be/handle/20.500.12942/722215
Autor:
Duy D. Nguyen, William F. Hooper, Timothy R. Chu, Heather Geiger, Jennifer M. Shelton, Minita Shah, Zoe R. Goldstein, Lara Winterkorn, Michael Sigouros, Jyothi Manohar, Jenna Moyer, David Wilkes, Rahul R. Singh, Weisi Liu, Andrea Sboner, Scott T. Tagawa, David M. Nanus, Jones T. Nauseef, Cora N. Sternberg, Ana M. Molina, Douglas Scherr, Giorgio Inghirami, Juan Miguel Mosquera, Olivier Elemento, Nicolas Robine, Bishoy M. Faltas
Advanced urothelial cancer is a frequently lethal disease characterized by marked genetic heterogeneity. In this study, we investigate the evolution of the genomic signatures caused by endogenous and external mutagenic stimuli and their interplay wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18ad4a48f070b30bae530ad731699491
https://doi.org/10.1101/2023.05.07.538753
https://doi.org/10.1101/2023.05.07.538753
Publikováno v:
European Urology Focus. 7:254-257
Prostate-specific membrane antigen (PSMA) is a clinically validated target for prostate cancer. A variety of PSMA-based therapies, including radionuclide- and cytotoxic drug-conjugated and cellular immune products, are in development, each with varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16f9f016a9b790d0a6a123632b9c0fbb
https://doi.org/10.1016/j.euf.2021.02.006
https://doi.org/10.1016/j.euf.2021.02.006
Autor:
Jones T. Nauseef, Michael Sun, Charlene Thomas, Mahelia Bissassar, Escarleth Fernandez, Zachary Davidson, Amie Patel, Angela Tan, Tessa A. Chamberlain, Kara Earle, Rebecca Wunder, Sabrina Guervil, Sandra H. Castellanos, Judith Stangl-Kremser, Peter S. Gregos, Joseph R. Osborne, Karla V. Ballman, Ana M. Molina, Cora N. Sternberg, David M. Nanus, Neil H. Bander, Scott T. Tagawa
Publikováno v:
Cancer Research. 83:CT014-CT014
Background: PSMA-based targeted radionuclide therapy is now a standard of care for mCRPC since approval of 177Lu-PSMA-617. Use of antibodies (e.g., J591) to target PSMA with higher potency radionuclides (e.g., 225Ac) impacts kinetics, biodistribution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d21c51cd499feb7cf709493b7a0c624
https://doi.org/10.1158/1538-7445.am2023-ct014
https://doi.org/10.1158/1538-7445.am2023-ct014
Autor:
Neil J Shah, Vaibhav G Patel, Xiaobo Zhong, Luis Pina, Jessica E Hawley, Emily Lin, Benjamin A Gartrell, Victor Adorno Febles, David R Wise, Qian Qin, George Mellgard, Himanshu Joshi, Jones T Nauseef, David A Green, Panagiotis J Vlachostergios, Daniel H Kwon, Franklin Huang, Bobby Liaw, Scott Tagawa, Philip Kantoff, Michael J Morris, William K Oh
Publikováno v:
JNCI cancer spectrum, vol 6, iss 3
Background TMPRSS2, a cell surface protease regulated by androgens and commonly upregulated in prostate cancer (PCa), is a necessary component for SARS-CoV-2 viral entry into respiratory epithelial cells. Previous reports suggested a lower risk of SA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8587fb98b8dc993f295884242068e9a
https://doi.org/10.1093/jncics/pkac035
https://doi.org/10.1093/jncics/pkac035
Publikováno v:
Journal of Thrombosis and Thrombolysis. 52:597-600
Catastrophic Antiphospholipid Syndrome (CAPS) is a life-threatening complication of APS requiring complex management to optimize patient outcome. We describe a 54-year-old man with APS with history of splanchnic vein thrombosis, a Factor II G20210A h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c57a8bc05e9e75bb65ffaeec5d4d56c
https://doi.org/10.1007/s11239-020-02343-w
https://doi.org/10.1007/s11239-020-02343-w
Autor:
Bastien Nguyen, Susan F. Slovin, Michael J. Morris, Dana E. Rathkopf, Jose Mauricio Mota, Philip W. Kantoff, Konrad H. Stopsack, Jessica Flynn, Daniel C. Danila, Jones T. Nauseef, David B. Solit, Wassim Abida, Ethan Barnett, Glenn Heller, Howard I. Scher, Nikolaus Schultz, Andreas Wibmer
Publikováno v:
JCO Precis Oncol
PURPOSE Alterations in DNA damage repair (DDR) genes occur in up to 25% of patients with metastatic castration-resistant prostate cancer (mCRPC) and may sensitize to platinum chemotherapy. We aimed to evaluate the efficacy of platinum-based chemother
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48698e18ade0f59097ac1afbacbd790c
https://doi.org/10.1200/po.19.00346
https://doi.org/10.1200/po.19.00346