Zobrazeno 1 - 10
of 1 061
pro vyhledávání: '"Jones RD"'
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
When a material that contains precipitates is deformed, the precipitates and the matrix may strain plastically by different amounts causing stresses to build up at the precipitate-matrix interfaces. If premature failure is to be avoided, it is theref
Modulation of L-type Ca(2+) current (I(Ca,L)) by H(+) ions in cardiac myocytes is controversial, with widely discrepant responses reported. The pH sensitivity of I(Ca,L) was investigated (whole cell voltage clamp) while measuring intracellular Ca(2+)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::341f69920d5d0845b8afc12dcb336c9d
https://ora.ox.ac.uk/objects/uuid:f8be6ac5-1b5b-4eec-9105-9ec6b639e843
https://ora.ox.ac.uk/objects/uuid:f8be6ac5-1b5b-4eec-9105-9ec6b639e843
BACKGROUND AND PURPOSE: Intracellular pH (pH(i)) in heart is regulated by sarcolemmal H(+)-equivalent transporters such as Na(+)-H(+) exchange (NHE) and Na(+)-HCO(3) (-) cotransport (NBC). Inhibition of NBC influences pH(i) and can be cardioprotectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7d4b56b67e4f094668da84d98c1f0b09
https://ora.ox.ac.uk/objects/uuid:6e939b16-72b4-43f8-a5dd-9b86cbc0c815
https://ora.ox.ac.uk/objects/uuid:6e939b16-72b4-43f8-a5dd-9b86cbc0c815
Acid extrusion on Na(+)-coupled pH-regulatory proteins (pH-transporters), Na(+)/H(+) exchange (NHE1) and Na(+)-HCO3(-) co-transport (NBC), drives Na(+) influx into the ventricular myocyte. This H(+)-activated Na(+)-influx is acutely up-regulated at p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3909f699f69582b57945601eaeddf2f0
https://ora.ox.ac.uk/objects/uuid:813c9303-ccca-47bf-bb7c-4bdb5361ce8c
https://ora.ox.ac.uk/objects/uuid:813c9303-ccca-47bf-bb7c-4bdb5361ce8c