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Concussion susceptibility is mediated by spreading depolarization-induced neurovascular dysfunction.

Autor: Parker E; Department of Medical Neuroscience, Dalhousie University, Faculty of Medicine, Halifax, NS, Canada.; Faculty of Medicine, Dalhousie University, Halifax, NS, Canada., Aboghazleh R; Department of Medical Neuroscience, Dalhousie University, Faculty of Medicine, Halifax, NS, Canada.; Department of Basic Medical Sciences, Al-Balqa Applied University, Al-Salt, Jordan., Mumby G; Department of Medical Neuroscience, Dalhousie University, Faculty of Medicine, Halifax, NS, Canada., Veksler R; Departments of Physiology and Cell Biology, Brain and Cognitive Sciences, The Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva, Israel., Ofer J; Departments of Physiology and Cell Biology, Brain and Cognitive Sciences, The Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva, Israel., Newton J; Department of Medical Neuroscience, Dalhousie University, Faculty of Medicine, Halifax, NS, Canada., Smith R; Department of Medical Neuroscience, Dalhousie University, Faculty of Medicine, Halifax, NS, Canada.; Faculty of Medicine, Dalhousie University, Halifax, NS, Canada., Kamintsky L; Department of Medical Neuroscience, Dalhousie University, Faculty of Medicine, Halifax, NS, Canada., Jones CMA; Department of Medical Neuroscience, Dalhousie University, Faculty of Medicine, Halifax, NS, Canada.; Faculty of Medicine, Dalhousie University, Halifax, NS, Canada., O'Keeffe E; Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland., Kelly E; FutureNeuro SFI Research Centre, The Royal College of Surgeons in Ireland, Dublin, Ireland.; Academic Unit of Neurology, Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland., Doelle K; Department of Medical Neuroscience, Dalhousie University, Faculty of Medicine, Halifax, NS, Canada., Roach I; Department of Medical Neuroscience, Dalhousie University, Faculty of Medicine, Halifax, NS, Canada., Yang LT; Department of Integrative Biology, University of California, Berkeley, Berkeley, CA 94720, USA., Moradi P; Department of Medical Neuroscience, Dalhousie University, Faculty of Medicine, Halifax, NS, Canada., Lin JM; Department of Integrative Biology, University of California, Berkeley, Berkeley, CA 94720, USA., Gleason AJ; Department of Integrative Biology, University of California, Berkeley, Berkeley, CA 94720, USA., Atkinson C; Department of Family Medicine, Dalhousie University, Halifax, NS, Canada., Bowen C; Department of Diagnostic Radiology, Dalhousie University, Halifax, NS, Canada.; Biomedical Translational Imaging Centre (BIOTIC), Queen Elizabeth ll Health Sciences Centre, Halifax, NS, Canada., Brewer KD; Department of Diagnostic Radiology, Dalhousie University, Halifax, NS, Canada.; Biomedical Translational Imaging Centre (BIOTIC), Queen Elizabeth ll Health Sciences Centre, Halifax, NS, Canada., Doherty CP; FutureNeuro SFI Research Centre, The Royal College of Surgeons in Ireland, Dublin, Ireland.; Academic Unit of Neurology, Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland., Campbell M; Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland., Clarke DB; Department of Medical Neuroscience, Dalhousie University, Faculty of Medicine, Halifax, NS, Canada.; Department of Surgery (Neurosurgery), Dalhousie University, Halifax, NS, Canada., van Hameren G; Department of Medical Neuroscience, Dalhousie University, Faculty of Medicine, Halifax, NS, Canada., Kaufer D; Department of Integrative Biology, University of California, Berkeley, Berkeley, CA 94720, USA.; Helen Wills Neuroscience Institute & Berkeley Stem Cell Center, University of California Berkeley, Berkeley, CA 94720, USA., Friedman A; Department of Medical Neuroscience, Dalhousie University, Faculty of Medicine, Halifax, NS, Canada.; Departments of Physiology and Cell Biology, Brain and Cognitive Sciences, The Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

Publikováno v: Brain : a journal of neurology [Brain] 2022 Jun 30; Vol. 145 (6), pp. 2049-2063.

Microbiome differential abundance methods produce different results across 38 datasets.

Autor: Nearing JT; Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada. jacob.nearing@dal.ca., Douglas GM; Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada., Hayes MG; Department of Mathematics and Statistics, Dalhousie University, Halifax, NS, Canada., MacDonald J; Department of Computer Science, Dalhousie University, Halifax, NS, Canada., Desai DK; Integrated Microbiome Resource, Dalhousie University, Halifax, NS, Canada., Allward N; Department of Civil and Resource Engineering, Dalhousie University, Halifax, NS, Canada., Jones CMA; Department of Pharmacology, Dalhousie University, Halifax, NS, Canada., Wright RJ; Department of Pharmacology, Dalhousie University, Halifax, NS, Canada., Dhanani AS; Integrated Microbiome Resource, Dalhousie University, Halifax, NS, Canada., Comeau AM; Integrated Microbiome Resource, Dalhousie University, Halifax, NS, Canada., Langille MGI; Integrated Microbiome Resource, Dalhousie University, Halifax, NS, Canada.; Department of Pharmacology, Dalhousie University, Halifax, NS, Canada.

Publikováno v: Nature communications [Nat Commun] 2022 Jan 17; Vol. 13 (1), pp. 342. Date of Electronic Publication: 2022 Jan 17.

Multi-omics differentially classify disease state and treatment outcome in pediatric Crohn's disease.

Autor: Douglas GM; Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada., Hansen R; Department of Paediatric Gastroenterology, Royal Hospital for Children, Glasgow, UK., Jones CMA; Department of Pharmacology, Dalhousie University, Halifax, NS, Canada., Dunn KA; Department of Biology, Dalhousie University, Halifax, NS, Canada., Comeau AM; CGEB-Integrated Microbiome Resource (IMR), Dalhousie University, Halifax, NS, Canada., Bielawski JP; Department of Biology, Dalhousie University, Halifax, NS, Canada., Tayler R; Department of Paediatric Gastroenterology, Royal Hospital for Children, Glasgow, UK., El-Omar EM; Department of Medicine, St George and Sutherland Clinical School, UNSW, Sydney, NSW, Australia., Russell RK; Department of Paediatric Gastroenterology, Royal Hospital for Children, Glasgow, UK., Hold GL; Department of Medicine, St George and Sutherland Clinical School, UNSW, Sydney, NSW, Australia., Langille MGI; Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada. morgan.g.i.langille@dal.ca.; Department of Pharmacology, Dalhousie University, Halifax, NS, Canada. morgan.g.i.langille@dal.ca.; CGEB-Integrated Microbiome Resource (IMR), Dalhousie University, Halifax, NS, Canada. morgan.g.i.langille@dal.ca., Van Limbergen J; Department of Pediatrics, Dalhousie University, Halifax, NS, Canada.

Publikováno v: Microbiome [Microbiome] 2018 Jan 15; Vol. 6 (1), pp. 13. Date of Electronic Publication: 2018 Jan 15.