Výsledky vyhledávání - "Jones, Winton D."

A convenient synthesis of 5-acyl-6-substituted 3-cyano-2(1H)-pyridinones

Autor: Jones Winton D, Schnettler Richard A, Edward W. Huber

Publikováno v: Journal of Heterocyclic Chemistry. 27:511-518

2-Dimethylaminomethylidene-1,3-diketones are useful synthons for the construction of 5-acyl-6-substituted-3-cyano-2(1H)-pyridinones. The reaction of these 1,3-diketones and the anion of cyanoacetamide gave the title compounds. When the 1,3 diketone c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::095f56f1a2fa727b558adb7a6d4686e0
https://doi.org/10.1002/jhet.5570270307

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Inhibition of angiogenesis in vitro and in ovo with an inhibitor of cellular protein kinases, MDL 27032

Autor: Doreen E. Cross-Doersen, Jones Winton D, Jerry A. Miller, Alan J. Bitonti, Paul S. Wright

Publikováno v: Journal of cellular physiology. 152(3)

Protein kinase C (PKC) was implicated as an important positive regulator of angio-genesis by studies showing that tumor promoting phorbol esters, which activate PKC, stimulate angiogenesis both in vitro and in vivo. Therefore, inhibitors of PKC might

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f4951ed8b85f6ea26ab689a04b9d28f
https://pubmed.ncbi.nlm.nih.gov/1380511

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Akademický článek

MDL 27,032 Relaxes Vascular Smooth Muscle and Inhibits Protein Kinase C.

Autor: Cheng, Hsien C., Robinson, Phillip J., Dage, Richard C., Jones, Winton D.

Publikováno v: Journal of Cardiovascular Pharmacology; Mar1991, Vol. 17 Issue 3, p445-455, 11p

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Akademický článek

A convenient synthesis of 5-acyl-6-substituted 3-cyano-2(1 H)-pyridinones.

Autor: Jones, Winton D., Schnettler, Richard A., Huber, Edward W.

Publikováno v: Journal of Heterocyclic Chemistry; Mar1990, Vol. 27 Issue 3, p511-518, 8p

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Synthesis of s-triazolocycloalkyl-, s-triazolobenzocycloalkyl-, and s-triazolocycloalkylhydrothiadiazines.

Autor: Albrecht, William L., Jones, Winton D., Sweet, F. William

Publikováno v: Journal of Heterocyclic Chemistry; Mar1978, Vol. 15 Issue 2, p209-215, 7p

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Inhibition of angiogenesis in vitro and in ovo with an inhibitor of cellular protein kinases, MDL 27032.

Autor: Wright, Paul S., Cross-Doersen, Doreen, Miller, Jerry A., Jones, Winton D., Bitonti, Alan J.

Publikováno v: Journal of Cellular Physiology; Sep1992, Vol. 152 Issue 3, p448-457, 10p

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Aminolysis and hydrolysis of chromonyl oxazolones and some condensation reactions of 2-methylchromone leading to novel chromones.

Autor: Jones, Winton D.

Publikováno v: Journal of the Chemical Society, Perkin Transactions 1 (0300922X); 1981, p344-348, 5p

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The synthesis of 5- and 6-acyl-2(1H)-pyrimidinones

Autor: Schnettler Richard A, Edward W. Huber, J. Martin Grisar, Jones Winton D

Publikováno v: Journal of Heterocyclic Chemistry. 24:1221-1223

The synthesis of 5-acyl-2(1H)-pyrimidinones is described. In addition, one example of the hitherto unknown 6-acyl-2(1H)-pyrimidinones has been prepared.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::73ea35c835846ccb49195eb963402f97
https://doi.org/10.1002/jhet.5570240456

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