Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jonay García-Luis"'
Autor:
Silvia Pérez-Yanes, Iria Lorenzo-Sánchez, Romina Cabrera-Rodríguez, Jonay García-Luis, Rodrigo Trujillo-González, Judith Estévez-Herrera, Agustín Valenzuela-Fernández
Publikováno v:
Cells, Vol 13, Iss 7, p 598 (2024)
Zika virus (ZIKV) infection and pathogenesis are linked to the disruption of neurogenesis, congenital Zika syndrome and microcephaly by affecting neural progenitor cells. Nonstructural protein 5 (NS5) is the largest product encoded by ZIKV-RNA and is
Externí odkaz:
https://doaj.org/article/c122ba960d6a4667b363c152bf5f07af
Autor:
Romina Cabrera-Rodríguez, Silvia Pérez-Yanes, Iria Lorenzo-Sánchez, Rodrigo Trujillo-González, Judith Estévez-Herrera, Jonay García-Luis, Agustín Valenzuela-Fernández
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13104 (2023)
HIV-1 has evolved a plethora of strategies to overcome the cytoskeletal barrier (i.e., actin and intermediate filaments (AFs and IFs) and microtubules (MTs)) to achieve the viral cycle. HIV-1 modifies cytoskeletal organization and dynamics by acting
Externí odkaz:
https://doaj.org/article/e77ea9eab71b4df6a6c67d39173ac432
Autor:
Romina Cabrera-Rodríguez, Silvia Pérez-Yanes, Iria Lorenzo-Sánchez, Judith Estévez-Herrera, Jonay García-Luis, Rodrigo Trujillo-González, Agustín Valenzuela-Fernández
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7658 (2023)
The transactive response DNA-binding protein (TARDBP/TDP-43) is known to stabilize the anti-HIV-1 factor, histone deacetylase 6 (HDAC6). TDP-43 has been reported to determine cell permissivity to HIV-1 fusion and infection acting on tubulin-deacetyla
Externí odkaz:
https://doaj.org/article/508c4cb1a9604a4a9e17383879c59bf1
Autor:
Agustín Valenzuela-Fernández, Romina Cabrera-Rodríguez, Concha Casado, Silvia Pérez-Yanes, María Pernas, Jonay García-Luis, Silvia Marfil, Isabel Olivares, Judith Estévez-Herrera, Rodrigo Trujillo-González, Julià Blanco, Cecilio Lopez-Galindez
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2172 (2022)
In the absence of antiviral therapy, HIV-1 infection progresses to a wide spectrum of clinical manifestations that are the result of an entangled contribution of host, immune and viral factors. The contribution of these factors is not completely esta
Externí odkaz:
https://doaj.org/article/6a1c4b76e28a4bbd8416d44bc7ae05e9
Autor:
Romina Cabrera-Rodríguez, Silvia Pérez-Yanes, Rafaela Montelongo, José M. Lorenzo-Salazar, Judith Estévez-Herrera, Jonay García-Luis, Antonio Íñigo-Campos, Luis A. Rubio-Rodríguez, Adrián Muñoz-Barrera, Rodrigo Trujillo-González, Roberto Dorta-Guerra, Concha Casado, María Pernas, Julià Blanco, Carlos Flores, Agustín Valenzuela-Fernández
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 6180 (2022)
The transactive response DNA-binding protein (TARDBP/TDP-43) influences the processing of diverse transcripts, including that of histone deacetylase 6 (HDAC6). Here, we assessed TDP-43 activity in terms of regulating CD4+ T-cell permissivity to HIV-1
Externí odkaz:
https://doaj.org/article/e20d8b360a12475eb7083b4735895af0
Autor:
Jonay García-Luis, Félix Machín
Publikováno v:
Genes, Vol 9, Iss 11, p 558 (2018)
Homologous recombination (HR) is a preferred mechanism to deal with DNA replication impairments. However, HR synapsis gives rise to joint molecules (JMs) between the nascent sister chromatids, challenging chromosome segregation in anaphase. Joint mol
Externí odkaz:
https://doaj.org/article/6f304304ae6447bfaeb2bb181f719cfb
Publikováno v:
PLoS Genetics, Vol 8, Iss 2, p e1002509 (2012)
The resolution of chromosomes during anaphase is a key step in mitosis. Failure to disjoin chromatids compromises the fidelity of chromosome inheritance and generates aneuploidy and chromosome rearrangements, conditions linked to cancer development.
Externí odkaz:
https://doaj.org/article/b6b35368c98d499e84cbf4b4a645b9b8
Autor:
Romina Cabrera-Rodríguez, Silvia Pérez-Yanes, Rafaela González-Montelongo, José M. Lorenzo-Salazar, Judith Estévez-Herrera, Jonay García-Luis, Antonio Íñigo-Campos, Luis A. Rubio-Rodríguez, Adrián Muñoz-Barrera, Rodrigo Trujillo-González, Roberto Dorta-Guerra, Concha Casado, María Pernas, Julià Blanco, Carlos Flores, Agustín Valenzuela-Fernández
The transactive response DNA-binding protein (TDP-43) is an important regulator of mRNA, being reported to stabilize the anti-HIV factor, histone deacetylase 6 (HDAC6). However, little is known about the role of TDP-43 in HIV infection. In this work,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fde93c4f21cdf4997318c5e24bf27a63
https://doi.org/10.1101/2021.12.06.471424
https://doi.org/10.1101/2021.12.06.471424
Autor:
Swathi Sudhakar, Erin Cutts, Christopher Cawood, Luis Aragón, David Rueda, Pilar Gutiérrez-Escribano, Gemma Lm Fisher, Jonay García-Luis
Condensin plays a central role in the organisation of chromosomes by compacting chromatin into loops during mitosis. Condensin achieves this through a loop extrusion mechanism that remains poorly understood. To identify the molecular steps of yeast c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90d3dcadcd67524c8d3f4243dc2c07ba
https://doi.org/10.21203/rs.3.rs-901482/v1
https://doi.org/10.21203/rs.3.rs-901482/v1
Chromosome segregation requires both the separation of sister chromatids and the sustained condensation of chromatids during anaphase. In yeast cells, cohesin is not only required for sister chromatid cohesion but also plays a major role in determini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2aeb50e186c0203729cfdfecc1166035
https://doi.org/10.1101/2021.08.27.457984
https://doi.org/10.1101/2021.08.27.457984